Results 211 to 220 of about 49,741 (289)

Biochemical and Biophysical Properties of Extracellular Matrix Nanofibers Modulate iPSC‐Derived Human Hepatocyte Maturation

Journal of Biomedical Materials Research Part A, Volume 113, Issue 10, October 2025.
ABSTRACT Human liver models grown in the lab are used for testing drug metabolism and toxicity, studying liver diseases, and developing new therapies. Induced pluripotent stem cell (iPSC)‐derived hepatocyte‐like cells (HLCs) provide a renewable alternative to scarce primary human hepatocytes (PHHs), but they remain functionally immature compared to ...
Yang Yuan, Liszt C. Madruga, Kristen Y. Cotton, Matt J. Kipper, Salman R. Khetani   +4 more
wiley   +1 more source

A Signal-On Microelectrode Electrochemical Aptamer Sensor Based on AuNPs-MXene for Alpha-Fetoprotein Determination. [PDF]

Sensors (Basel)
Su X, Chen J, Wu S, Qiu Y, Pan Y.
europepmc   +1 more source

Prognostic Value of a Novel Model for Hepatocellular Carcinoma Patients Undergoing Transarterial Chemoembolization

Journal of Clinical Laboratory Analysis, Volume 39, Issue 19, October 2025.
A prognosis model (PI score), which consisted of neutrophil‐lymphocyte ratio (NLR), γ‐glutamyl transpeptidase (GGT), alpha‐fetoprotein (AFP), and TNM stage, was constructed. The PI score had excellent predictive value for HCC patients undergoing TACE and was superior to TNM and BCLC.
Cailing Ye, Yaqiong Chen, Jiahao Chen, Zhongcheng Chen, Wensi Chen, Suqing Zhao, Bo Hu, Zhaoxia Li   +7 more
wiley   +1 more source

The Expression of Alpha-Fetoprotein in Human Blastocoel Fluid-Conditioned Media In Vitro: A Proof of Concept Study. [PDF]

Int J Mol Sci
Kavoussi SK, Chen SH, Wininger JD, Lal A, Roudebush WE, Kavoussi PK, Esqueda AS, Chen J, Chosed RJ.   +8 more
europepmc   +1 more source

Blood Biomarker-Based Predictive Indicator for Liver Metastasis in Alpha-Fetoprotein-Producing Gastric Cancer and Multi-Omics Tumor Microenvironment Insights. [PDF]

Adv Sci (Weinh)
Ding Y, Chen Y, Zhang J, Wang Q, Zhu S, Jiang J, He C, Wang J, Tou L, Zheng J, Chen B, Hu S, Yu X, Wang H, Lu Y, Kong M, Chen Y, Wang H, Zhang H, Xu H, Teng F, Shen X, Xu N, Ruan J, Zhou Z, Lu J, Teng L.   +26 more
europepmc   +1 more source

Further studies on the mechanism of suppression of human lymphocyte transformation by human alpha fetoprotein

, 1980
Stanley Yachnin, Keyoumars Soltani, Eva P. Lester   +2 more
openalex   +1 more source

Monocarboxylate Transporter‐1 Is Dispensable for Hepatocellular Carcinoma Development

Molecular Carcinogenesis, Volume 64, Issue 10, Page 1724-1734, October 2025.
ABSTRACT Hepatocellular carcinoma (HCC) is the most prevalent type of liver cancer and the deadliest liver disease. It is imperative to understand the underlying molecular mechanisms involved in the development of HCC. Monocarboxylate transporter‐1 (MCT1) is a proton‐coupled protein that facilitates the bidirectional transport of monocarboxylates, such
Shaimaa A. Gad, Bryan Bridgeman, Kyle Boedeker, Xianzhong Ding, Wei Qiu   +4 more
wiley   +1 more source

A Route to the Colorimetric Detection of Alpha-Fetoprotein Based on a Smartphone. [PDF]

Micromachines (Basel)
Liu J, Geng Q, Geng Z.
europepmc   +1 more source

alpha-Fetoprotein gene expression. Partial DNA sequence and COOH-terminal homology to albumin.

, 1980
Michael A. Innis, David L. Miller
openalex   +1 more source

Advancements and Challenges in Salivary Metabolomics for Early Detection and Monitoring of Systemic Diseases

MedComm, Volume 6, Issue 10, October 2025.
Salivary metabolomics offers a noninvasive and effective approach for early disease detection and monitoring. Salivary metabolites reflect systemic metabolism, inflammation, and external factors such as diet and stress. Advance in bioinformatics and machine learning facilitates the identification of metabolic biomarkers with high diagnostic accuracy ...
Xinyuan Zhao, Xu Chen, Zihao Zhou, Jiarong Zheng, Yunfan Lin, Yucheng Zheng, Rongwei Xu, Shen Hu, Li Cui   +8 more
wiley   +1 more source