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Alpha-Fetoprotein

Epidemiology, 1993
Beginning in 1977, numerous studies have reported an association between high levels of maternal serum alpha-fetoprotein, measured in early pregnancy, and low birthweight and perinatal death. It has been suggested, however, that these findings may be explained by bias.
Linda S. Lustig   +6 more
openaire   +4 more sources

Biochemical characterization of bovine alpha-fetoprotein and comparison with human alpha-fetoprotein

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1994
This study compares the molecular, charge and lectin microheterogeneity of bovine alpha-fetoprotein (bAFP) with human (h) AFP. Molecular weights of bAFP (81 kDa) and hAFP (69 kDa) were detected by Western immunoblotting. Marked crossreactivity was found between bAFP and hAFP by Western immunoblotting but no crossreactivity was noticed by ...
Yongsheng He, Brooks A. Keel
openaire   +3 more sources

Hereditary persistence of alpha-fetoprotein

Gastroenterology, 1990
Persistently elevated alpha-fetoprotein levels were found in a 43-yr-old man in the absence of any specific pathology. Elevated serum alpha-fetoprotein levels were subsequently found in three first-degree relatives, two siblings, and one daughter. This represents the third documented family with hereditary persistence of alpha-fetoprotein. The pedigree
Frank Greenberg   +2 more
openaire   +3 more sources

ALPHA-FETOPROTEIN IN PREGNANCY

The Lancet, 1973
This letter presents a comparison of maternal serum alpha fetoprotein (AFP) levels in 2 groups of pregnant women of various parity at any stage of pregnancy. A total of 130 serum samples from primipara and multipara women were compared by radioimmunoassay; 64 sera were from primipara and 66 from multipara.
openaire   +3 more sources

Species cross-reaction of alpha-fetoproteins and break-down of the tolerance to alpha-fetoprotein by immunization with heterologous alpha-fetoprotein.

Tumor research, 1973
Immunological character of alpha fetoprotein (AFP) was investigated in respect to immunological relationship of human and animal AFP; responses to the injection of homologous AFP; responses to injection of human AFP; and effects of maternal antibody against AFP to fetuses.
Shinzo Nishi   +2 more
openaire   +3 more sources

ALPHA-FETOPROTEIN IN ANTENATAL DIAGNOSIS

The Lancet, 1973
Based on 10 cases with abnormally high alpha fetoprotein (AFP) levels during pregnancy the following combinations of the AFP concentrations in maternal serum and amniotic fluid seem to be possible in fetal distress: 1) High maternal serum and high amniotic fluid AFP in cases with chronic fetal distress or intrauterine death.
Markku Seppälä, Erkki Ruoslahti
openaire   +3 more sources

Alpha fetoprotein in embryonal hepatoblastoma

The Journal of Pediatrics, 1970
Summary Fetoprotein, normally present only in earlyfetal life, is reported here in the serum of a patient with hepatoblastoma. The serum concentration in this patient was similar to levels seen in early fetal life and is higher than that reported in association with most cases of hepatocellular carcinoma, regardless of age. The high fetoprotein level
Ruth Andrea Seeler, M.E. Alpert
openaire   +3 more sources

Alpha-fetoprotein in animal reproduction

Research in Veterinary Science, 2019
Alpha-fetoprotein (AFP) is a serum glycoprotein with structural and physico-chemical properties similar to albumin. However, the exact physiological functions of AFP remain unknown; those known to date include markers to pathological conditions including neoplastic and non-neoplastic diseases, antioxidant effects, growth regulator in different cells ...
RIZZO A   +3 more
openaire   +4 more sources

Alpha-Fetoprotein in Hepatitis

Annals of Internal Medicine, 1974
Excerpt To the editor: During the recent years several investigators (1-5), using radioimmunoassay, have shown the presence of alphafetoprotein (AFP), not only in the fetal period or in the patient...
openaire   +2 more sources

Radioimmunassay of ovine alpha-fetoprotein

Journal of Immunological Methods, 1978
Highly purified ovine alpha-fetoprotein (AFP) was used both for radioisotope labelling and as the reference standard in the double antibody radioimmunoassay of ovine AFP. The sensitivity of the assay is 2 ng/ml which is about 8000 times more sensitive than radialimmunodiffusion assay.
F.L. Lorscheider, D.M. Hay, P.C.W. Lai
openaire   +3 more sources

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