Results 121 to 130 of about 10,488 (304)

Clinical Outcomes of Reduced‐Dose Cabozantinib as Third‐ or Later‐Line Therapy After Immune Checkpoint Inhibitors in Advanced Hepatocellular Carcinoma: A Real‐World Study

open access: yesHepatology Research, EarlyView.
In this real‐world post‐ICI setting, cabozantinib demonstrated meaningful clinical activity even at reduced doses, with disease control achieved in nearly half of patients. Importantly, preserved liver function (Child–Pugh class A) was the only determinant of both disease control and overall survival.
Teiji Kuzuya   +13 more
wiley   +1 more source

Treatment of Hepatocellular Carcinoma Using Endoscopic Ultrasound‐guided Radiofrequency Ablation: A Case Series

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract Endoscopic ultrasound‐guided radiofrequency ablation (EUS‐RFA) is an emerging technique for treating pancreatic and neuroendocrine tumors in patients who are not candidates for surgery. However, there is limited evidence of EUS‐RFA in hepatic cancers.
Yogesh Harwani   +4 more
wiley   +1 more source

A Case of Obstructive Jaundice due to Bile Duct Tumor Thrombus of Hepatocellular Carcinoma Diagnosed by Peroral Cholangioscopy

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
Abstract While hepatocellular carcinoma (HCC) often invades the portal or hepatic vein to form tumor thrombus, tumor thrombus in the bile duct is rare. In such cases, differentiation from intrahepatic cholangiocarcinoma is difficult, and the tumor often appears as a smooth, yellowish‐white, polypoid mass within the bile duct lumen.
Keisuke Kinoshita   +9 more
wiley   +1 more source

Intramucosal Alpha‐Fetoprotein‐producing Early Gastric Cancer Without Vascular Invasion or Metastasis Diagnosed After Endoscopic Submucosal Dissection: A Case Report and Literature Review

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Alpha‐fetoprotein‐producing gastric cancer (AFPGC) is a rare histological subtype of gastric cancer that is often diagnosed at an advanced stage. In the present case, an elevated lesion was detected in the gastric antrum during upper gastrointestinal endoscopy screening and diagnosed as early gastric cancer of cT1a.
Kohei Uyama   +5 more
wiley   +1 more source

A Case of Pancreatic Neuroendocrine Tumor Growing Intraductal Extension toward the Main Pancreatic Duct Complicated by Thrombocytopenia: Diagnostic Challenges and Management Strategy

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT We present a rare and diagnostically challenging case of a pancreatic neuroendocrine tumor (pNET) with intraductal growth into the main pancreatic duct (MPD), complicated by severe thrombocytopenia due to myelodysplastic syndrome. A 37‐year‐old male presented with thrombocytopenia.
Koichi Soga   +9 more
wiley   +1 more source

A Case of Gastric Metastasis of Renal Cell Carcinoma Resected by Endoscopic Submucosal Dissection After Endoscopic Follow‐up of Morphological Changes

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT A 62‐year‐old man underwent partial nephrectomy for right renal cell carcinoma (RCC). Four years later, esophagogastroduodenoscopy revealed gastric mucosal redness with a smooth surface. Two more years later, the red lesion showed a morphological change to a reddish elevation, which prompted a biopsy.
Yuichi Fukami   +9 more
wiley   +1 more source

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