Results 191 to 200 of about 3,079 (276)

Should PNPO Deficiency Be Treated In Utero? Clinical Findings From Prenatal Pyridoxine Therapy

JIMD Reports, Volume 67, Issue 3, May 2026.
ABSTRACT Pyridox(am)ine‐5′‐phosphate oxidase (PNPO) deficiency is characterized by early‐onset epileptic encephalopathy refractory to standard antiseizure medications. It is caused by variants in the PNPO gene, resulting in deficient PNPO enzyme activity, which normally converts pyridoxine‐5′‐phosphate and pyridoxamine‐5′‐phosphate (two vitamers of ...
Chloé de Puyraimond, Samia Pichard, Muriel Girard, Julian Delanne, Laurence Faivre, Apolline Imbard, Amandine Baurand, Jean‐François Benoist, Philippa B. Mills, Peter T. Clayton, Manuel Schiff   +10 more
wiley   +1 more source

[Novel clinical insights and frontier issues in alpha- fetoprotein-producing gastric cancer]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Luo B, Liu H, Xie W, Gong W.
europepmc   +1 more source

Phase IIb Trial for the Palliative Treatment of Patients With Primary Hepatic Malignancy Unable to Receive Curative Treatment: Efficacy of Colchicine

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 5, May 2026.
ABSTRACT This trial was to evaluate the efficacy and the safety of colchicine for the palliative treatment of patients with primary hepatic malignancy unable to receive curative treatment. Forty hepatocellular carcinoma (HCC) patients and two intrahepatic cholangiocarcinoma (ICC) patients signed the informed consents.
Zu‐Yau Lin, Ming‐Lun Yeh, Po‐Cheng Liang, Shinn‐Cherng Chen, Chung‐Feng Huang, Jee‐Fu Huang, Chia‐Yen Dai, Ming‐Lung Yu, Wan‐Long Chuang   +8 more
wiley   +1 more source

XGBoost-based analysis of maternal and biochemical factors associated with spontaneous preterm birth: a retrospective cohort study. [PDF]

BMC Pregnancy Childbirth
Gao Y, Huang X, Tan C, Chen L, Zhao X, Yang J.   +5 more
europepmc   +1 more source

Whole‐Genome Bisulfite Sequencing Identifies Blood‐Based DNA Methylation Biomarker for Hepatocellular Carcinoma

Molecular Carcinogenesis, Volume 65, Issue 5, Page 603-614, May 2026.
ABSTRACT Functional DNA methylation abnormalities are a hallmark of human cancers and may be a promising biomarker for their early diagnosis. Moreover, the largest methylation differences can improve the sensitivity of noninvasive diagnoses of solid tumors.
Junsheng Zhao, Sijia Shen, Junjie Zhang, Ying Xu, Jing Peng, Hainv Gao, Lanjuan Li   +6 more
wiley   +1 more source

The Association and diagnostic value between Maternal Serum Placental Markers and Placenta Previa. [PDF]

Eur J Obstet Gynecol Reprod Biol X
Ma P, Hu T, Chen Y.
europepmc   +1 more source

Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies

MedComm, Volume 7, Issue 5, May 2026.
The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He, Sinan Xie, Kunlin Xie, Fengwei Gao, Yunshi Cai, Yan Huang, Chang Liu, Hong Wu, Yinghao Lyu, Tian Lan   +9 more
wiley   +1 more source

AADN score: Predicting response to transarterial chemoembolization, sintilimab and lenvatinib in patients with hepatocellular carcinoma. [PDF]

World J Gastroenterol
Zhang X, Liao MJ, Ren LY, Qin WY, Mu SW, She SP, Fei R, Cong X, Zhou YP, Chen DB, Chen HS.   +10 more
europepmc   +1 more source

Primary Hepatoid Adenocarcinoma of the Lung With Signet Ring Cell Differentiation and Widespread Osseous Metastases: A Case Report

Respirology Case Reports, Volume 14, Issue 5, May 2026.
We present a case of hepatoid adenocarcinoma in the lung which was initially misdiagnosed as pneumonia and rapidly progressed to widespread metastatic disease. This case emphasises the diagnostic difficulty, radiological and histopathologic characteristics, and aggressive clinical behaviour of this rare tumour and underscores the need for early ...
Rami Khader, Esraa Elhakim, Mohammad Bdair, Rajaa Abu Sultan, Ameed Khader, Mousa Almasalma, Saleh Ferwana, Mohammed Z. A. Baraka   +7 more
wiley   +1 more source

Tungsten Oxide-Mediated Photocatalytic Silver Enhancement in a QCM Immunosensor for Alpha-Fetoprotein Detection. [PDF]

Biosensors (Basel)
Kim HS, Cho YG, Lee SS.
europepmc   +1 more source