Extended‐Gate‐Type Organic Field‐Effect Transistors for Label‐Free Immunosensing
An antibody‐functionalized extended‐gate organic field‐effect transistor converts interfacial recognition into an electrical response while separating the sensing interface from the organic semiconductor. This Perspective summarizes proof‐of‐concept studies, surface‐engineering and device‐integration strategies, and the remaining challenges for ...
Yui Sasaki, Tsuyoshi Minami
wiley +1 more source
Immunotherapy-based neoadjuvant treatment of gastric cancer with elevated serum AFP: a case report. [PDF]
Liu Y +12 more
europepmc +1 more source
Safe and Stable Germline Transmission of MSTN Mutations in Cattle
ABSTRACT With the global population expected to reach 10 billion by 2050, sustainable livestock production is critical. Gene editing of the myostatin (MSTN) gene represents a promising strategy to enhance muscle growth in cattle. In this study, MSTN‐mutated founder (F0) cows were used to generate F1 offspring via ovum pick‐up, in vitro fertilization ...
Gyeong‐Min Gim +10 more
wiley +1 more source
Management and Prognosis of HCC Patients With Elevated Tumor Markers but no Imaging Recurrence After Radiofrequency Ablation. [PDF]
Moriyama M +9 more
europepmc +1 more source
ABSTRACT Background and Aims Genome‐wide association studies (GWAS) that were previously conducted in European and Asian cohorts have identified numerous genetic risk factors for hepatocellular carcinoma (HCC) and its precursors and risk factors. A polygenic risk score (PRS) composed of these key SNPs for HCC may be useful for risk stratification in ...
Priya B. Shetty +13 more
wiley +1 more source
Serum Midkine as a Biomarker for Hepatocellular Carcinoma Treatment Response and Prognostication. [PDF]
Luo Y, Lu Q, Huang J, Jiang L.
europepmc +1 more source
Human‐umbilical‐cord‐mesenchymal‐stem‐cell‐derived exosomes amplify anti‐hepatocellular‐carcinoma effects of gallic acid from Compound Muji Granules. This work identifies absorbed herbal constituents and reveals modulation of IL‐17/MAPK/p53 signaling in HCC organoid models, offering mechanistic insights for exosome‐assisted traditional‐medicine ...
Qiang Zhang +12 more
wiley +1 more source
Prognostic value of combined FIB-4 and AFP in predicting survival after hepatectomy for hepatocellular carcinoma: a multicenter cohort study. [PDF]
Yang Y +5 more
europepmc +1 more source
ABSTRACT In an infant with cholestasis and recurrent hypoglycemia, the combination of hypercitrullinemia, hypermethioninemia, and hyperthreoninemia should prompt testing for citrin deficiency, because early metabolic and genetic diagnosis allows targeted nutritional treatment and rapid clinical improvement.
Julien Neveu +4 more
wiley +1 more source
Predictive Value of On-Treatment Alpha-Fetoprotein Change for Lenvatinib Response in Patients with Hepatocellular Carcinoma: A Real-World Retrospective Study in Vietnam. [PDF]
Hoang NT +7 more
europepmc +1 more source

