Results 151 to 160 of about 835,413 (266)

Atezolizumab Plus Bevacizumab Treatment for Patients With Hepatocellular Carcinoma in the Barcelona Clinic Liver Cancer B2 Stage

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim The optimal treatment strategy for patients with intermediate‐stage hepatocellular carcinoma beyond the up‐to‐seven criteria (Barcelona Clinic Liver Cancer B2) remains uncertain. Although transarterial chemoembolization has long been the standard of care, its efficacy is limited in this subgroup, and systemic therapies have ...
Keishi Ouchi, Masashi Ninomiya, Mio Tsuruoka, Jun Inoue, Atsushi Hiraoka, Kosuke Sato, Kotaro Doi, Kengo Watanabe, Tomoya Sasazaki, Takayoshi Oikawa, Kei Endo, Tamami Abe, Masashi Fujita, Kazumichi Abe, Tomohiro Katsumi, Wataru Sato, Chikara Iino, Nobukazu Tanabe, Hiroshi Numao, Hiromasa Ohira, Hidekatsu Kuroda, Yoshiyuki Ueno, Atsushi Masamune   +22 more
wiley   +1 more source

Early Changes in Lymphocyte Counts Predict Clinical Outcomes in Hepatocellular Carcinoma Treated With Durvalumab Plus Tremelimumab

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Durvalumab plus tremelimumab (Dur/Tre) has shown promising efficacy in advanced hepatocellular carcinoma (HCC), but predictive biomarkers remain unclear. This study aimed to determine whether early changes in peripheral blood lymphocyte counts during Dur/Tre therapy can predict clinical outcomes.
Yuichi Honma, Shigeo Shimose, Takanori Ito, Issei Saeki, Joji Tani, Takanori Matsuura, Tetsu Tomonari, Yasuto Takeuchi, Nobuhito Taniki, Kyo Sasaki, Ryu Sasaki, Takeshi Hatanaka, Satoru Kakizaki, Naoki Yoshioka, Takehito Naito, Mamiko Takeuchi, Tetsuya Yasunaka, Masahiro Sakata, Hideki Iwamoto, Tomotake Shirono, Satoshi Itano, Norikazu Tanabe, Takafumi Yamamoto, Atsushi Naganuma, Yuki Kanayama, Hisamitsu Miyaaki, Sohji Nishina, Nobuhiro Nakamoto, Motoyuki Otsuka, Tetsuji Takayama, Yuzo Kodama, Hideki Kobara, Taro Takami, Hiroki Kawashima, Takumi Kawaguchi, Masaru Harada, Hepatology InVestigator Experts in Japan (HIVE‐J) Study Group   +36 more
wiley   +1 more source

Primary gastric mixed germ cell tumor in an infant: the pivotal role of dynamic alpha-fetoprotein surveillance in unmasking occult malignancy. [PDF]

BMC Pediatr
Shen Q, Wang S, Wang C, Liu X, Wu H, Zhou C, Li T, Zhou J, Yin H.   +8 more
europepmc   +1 more source

20th Anniversary of human‐induced pluripotent stem cells and the role of microscopy

Journal of Microscopy, EarlyView.
Abstract It has been 20 years since the pioneering work of Shinya Yamanaka and Kazutoshi Takahashi at Kyoto University led to the first successful generation of induced pluripotent stem cells (iPSCs) from mouse embryonic and adult fibroblast cells. iPSCs have the capacity to differentiate into any type of cell in the human body, and as such, they have ...
Philomena Hallford, Colette J. Mustard, Nicole Brace, Antonia L. Pritchard   +3 more
wiley   +1 more source

Integrated Histopathologic and Targeted Genomic Characterization of Gastric Adenocarcinomas with Yolk Sac Tumor Differentiation. [PDF]

Int J Mol Sci
Di Mauro A, Rega RA, Sorrentino R, Falanga A, Leongito M, Albino V, Belli A, D'Arbitrio I, Simonelli S, Cecio R, Tafuto S, Nasti G, Ottaiano A, Tatangelo F.   +13 more
europepmc   +1 more source

Kinematic‐calcium loops unravel impaired excitation–contraction coupling in MELAS‐affected cardioids

The Journal of Physiology, EarlyView.
Abstract figure legend Representation of kinematic and calcium transient loop with respect to traditional time coplotting. Abstract Impaired Ca2+ handling, and in particular leakage from the sarcoplasmic reticulum, is a critical mechanism in metabolic diseases affecting the heart.
Margherita Burattini, Annalinda Pisano, Maria Gemma Pignataro, Giulia d'Amati, Silvana Pinelli, Minh Long Hoang, Francesco Paolo Lo Muzio, Michele Miragoli   +7 more
wiley   +1 more source

Second trimester quad test for fetal down syndrome screening as a predictor of spontaneous preterm birth in a developing country: a population-based study. [PDF]

BMC Pregnancy Childbirth
Ruenpeng P, Luewan S, Sirilert S, Kamlungkuea T, Parapob N, Wanapirak C, Tongsong T.   +6 more
europepmc   +1 more source

α-Fetoprotein

Japanese Journal of Clinical Chemistry, 1974
OTSUKA, SACHIO, IRIE, MINORU
openaire   +1 more source

Underestimation of Subserosal Invasion in Early Gastric Cancer‐Like Advanced Gastric Carcinoma With Focal Enteroblastic Differentiation: A Case Report

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Early gastric cancer (EGC)‐like advanced gastric cancer (AGC) is a rare entity that mimics superficial disease despite deep invasion. We report a case of EGC‐like AGC with focal enteroblastic differentiation in which subserosal invasion was underestimated because of its superficially appearing endoscopic features.
Akira Tomioka, Kankei Fujimoto, Kei Sugimoto, Takayuki Yamazaki, Nanoka Chiya, Yumi Mashimo, Tomonori Kawasaki, Tomio Arai, Shomei Ryozawa   +8 more
wiley   +1 more source

Diagnostic accuracy of surveillance tests for hepatocellular carcinoma in cirrhosis: a systematic review and network meta-analysis. [PDF]

BMJ Open Gastroenterol
Rogers G, Derezea E, Sadler L, Wang H, Cramp ME, Ryder SD, Watt K, Whiting P, Rogers M, Bell J, Oppe F, Stein K, Welton NJ, Jones HE.   +13 more
europepmc   +1 more source