ABSTRACT Background and Aims Accurate histological differentiation between hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) is essential for selecting appropriate treatment. Endoscopic ultrasound‐guided tissue acquisition (EUS‐TA) is increasingly used for focal liver lesions; however, comparative data on its diagnostic ...
Yuichi Takano +11 more
wiley +1 more source
Case report: Spatiotemporal HER2 heterogeneity in AFP-producing gastric cancer: navigating long-term survival with molecularly-guided therapy in a refractory case. [PDF]
Diao Y, Yin H, Sun X, Dong Q, Zhang J.
europepmc +1 more source
Proteomic signatures of equine dental tooth tissues in ageing and disease
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen +8 more
wiley +1 more source
Hereditary Persistence of Alpha-Fetoprotein and Safe Application of Growth Hormone in Familial Short Stature: A Case Report. [PDF]
Guo S, Zhang J, Chen Q, Yu Y, Ma H.
europepmc +1 more source
ABSTRACT Introduction Sertoli cell tumors are rare testicular sex cord‐stromal tumors, and clinically malignant behavior is uncommon. We report a rapidly progressive metastatic Sertoli cell tumor associated with an APC mutation. Case Presentation A 27‐year‐old man with familial adenomatous polyposis (FAP) presented with painless right scrotal ...
Kotaro Obayashi +9 more
wiley +1 more source
Diagnostic value of Midkine and AFP in the detection of hepatocellular carcinoma: A systematic review and meta-analysis. [PDF]
Lubis M +3 more
europepmc +1 more source
ABSTRACT Alcohol‐related hepatocellular carcinoma is an increasingly prevalent consequence of alcohol use and the often‐silent progression of alcohol‐related liver disease. A substantial proportion of patients with alcohol‐related hepatocellular carcinoma are diagnosed at an advanced stage, frequently because underlying liver disease has not been ...
Victoria Mignot +3 more
wiley +1 more source
HCC-Derived Alpha-Fetoprotein Impairs Bone Regeneration by Impairing Autophagic Flux and Promoting Runx2 Degradation in Osteoblasts. [PDF]
Yun HM, Park KR.
europepmc +1 more source
Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger‐1
The classical zinc finger (ZF) protein MZF1 uses two ZF clusters to achieve metal‐dependent and gene‐specific promoter recognition. The differential redox stability and modular utilization of the two ZF clusters enable MZF1 to regulate cerebrovascular, neuronal, and cancer‐related transcriptional programs.
Yunha Hwang +5 more
wiley +1 more source
Proposal for Modified Alpha Fetoprotein Use in Hepatocellular Carcinoma Surveillance: Analysis of the 2018-2020 National Cancer Screening Program. [PDF]
Yu S, Kim S, Kim H, Lee HR, Choi J.
europepmc +1 more source

