Results 41 to 50 of about 10,488 (304)

Pseudotumor of the Omentum Associated with Migration of the Ingested Crab-Leg [PDF]

, 2012
Foreign body ingestion is not uncommon in clinical practice, and it may occasionally lead to penetration injuries. Emergency physicians and radiologists sometimes fail to obtain complete histories including ingestion and may overlook the possibility of ...
Chung, Goh, Han-Jin Cho, Jong Hak Park, Law, Li, Liu, Otagiri, Santos, Su-Jin Kim, Sung Woo Lee, Sung Woo Moon, Yamamoto, Zissin   +13 more
core   +2 more sources

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source

Study on the Value of Oligosaccharide Chain and Alpha-fetoprotein for Risk Screening and Diagnosis of Hepatitis B Virus-related Hepatocellular Carcinoma [PDF]

Zhongguo quanke yixue
Background Hepatocellular carcinoma (HCC) is the main pathological type of primary liver cancer (PLC) and is closely associated with Hepatitis B virus (HBV) infection.
ZHANG Yun, CAI Xinyi, DING Jingnuo, LU Shengwei, CHEN Cuiying, WU Tingting, ZHANG Junli, ZHAO Weifeng
doaj   +1 more source

Ultrasound- guided fine needle aspiration cytology and cell block in the diagnosis of focal liver lesions at Khartoum Hospital, Sudan [PDF]

, 2013
Background: The appropriate clinical management of various hepatic lesions depends on accurate diagnosis. Fine needle aspiration and cell block have gained popularity because they are convenient, minimally invasive, quick and have good performance ...
Abdullhamid, M, Adam, I, Elsiddig, S, Gasim, GI, Mohmmed, AA   +4 more
core   +2 more sources

Targeting the Notch1‐YY1‐ICAM1 Signaling Axis Enhances the Efficacy of Immunotherapy in HCC by Activating CD8+ T‐Cell‐Driven Cancer Cell Pyroptosis

Advanced Science, EarlyView.
In hepatocellular carcinoma (HCC), aberrantly activated Notch1 signaling induces its target gene YY1, which impairs immunotherapy efficacy by suppressing tumor cell‐ICAM1‐driven T cell activation and the mediated pyroptosis of T cells against tumor cells.
Ke Zhu, Fa‐Peng Zhang, Chao Qin, Zhi‐Xiao Song, Cai‐Ni Yang, Shu‐Sheng Lin, Xian‐Huan Yu, Wen‐Rui Wu, Chao‐Qun Liu, Chao Liu, Lei‐Bo Xu   +10 more
wiley   +1 more source

Male-like sexual behavior of female mouse lacking fucose mutarotase [PDF]

, 2010
Background Mutarotases are recently characterized family of enzymes that are involved in the anomeric conversions of monosaccharides. The mammalian fucose mutarotase (FucM) was reported in cultured cells to facilitate fucose utilization and incorporation
B Attardi, C Bodo, C De Mees, CD Toran-Allerand, CH Hubscher, Chankyu Park, D Park, D Pfaff, D Restrepo, Dae-sik Lim, DJ Becker, Dongkyu Park, Dongwook Choi, E Ruoslahti, F Herve, FS vom Saal, G Ashwell, GJ Mizejewski, GJ Mizejewski, H Buteau-Lozano, HE Murrey, I Rodriguez, J Bakker, J Bakker, J Uriel, J Weisz, JB Becker, JP Raynaud, JR Wilson, Junghoon Lee, L Savu, M Olsson, M Yanase, ME Baker, MJ Baum, MM McCarthy, N Bayati, P Gabant, PJ Johnson, PL Smith, R Rampal, RB Simerly, RB Simerly, RB Simerly, RB Simerly, RB Simerly, RG Janzen, S Ogawa, S Ogawa, SJ Wiegand, SK Amateau, SK Swartz, SS Leong, T de Vries, T Nakagawa, T Okajima, WT Swaney, Y Luo, Z Wang   +58 more
core   +3 more sources

Disrupting the Formation of YAP Condensates Promotes the Activation of AMPKα to Inhibit the Progression of Primary Liver Cancer

Advanced Science, EarlyView.
This study systematically investigates the function and molecular mechanisms of YAP phase separation in multiple primary liver cancers. These findings provide novel insights into phase separation‐mediated primary liver cancer development and validate targeted disruption of this process as an effective therapeutic strategy for primary liver cancer ...
Shuang‐Zhou Peng, Jia‐Jia Liang, Yun‐Feng Zhan, Wei‐Xun Wu, Wan‐Li Xu, Xiao‐Kun Zhang, Li‐Jun Cai, Fu‐Quan Jiang   +7 more
wiley   +1 more source

Cancer: The Great Challenge for Immunology [PDF]

, 1977
The existence of immunity to cancer was postulated by the eminent scientists who helped to establish the discipline of immunology. In 1907 Clowes suggested that human resistance to cancer resulted from what we today call “immune surveillance.” During the
Goldstein, Gerald
core   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Second trimester serum tests for Down's Syndrome screening [PDF]

, 2012
Background Down's syndrome occurs when a person has three copies of chromosome 21 - or the specific area of chromosome 21 implicated in causing Down's syndrome - rather than two. It is the commonest congenital cause of mental retardation.
Alfirevic, Zarko, Alldred, S. Kate, Deeks, Jonathan J., Guo, Boliang, Neilson, James P.   +4 more
core   +1 more source