Results 31 to 40 of about 45,966 (272)

Bloating and gas formation: modern opportunities for treatment

Лечащий Врач, 2021
Bloating is a subjective feeling of excessive gas formation and passage of gasses. It is more common in patients with gastrointestinal disorders. For therapy of disorders involving excessive gas formation, fermentative nutraceutical containing alpha ...
L. I. Butorova, N. G. Kadnikova, M. A. Osadchuk, T. E. Plavnik, G. M. Tokmulina   +4 more
doaj  

Multi-response modeling of reaction-diffusion to explain alpha-galactoside behavior during the soaking-cooking process in cowpea [PDF]

, 2018
A modelling approach was developed to better understand the behavior of the flatulence-causing oligosaccharides in cowpea seeds during isothermal water soaking-cooking process.
Alter, Pascaline, Bohuon, Philippe, Briffaz, Aurélien, Coffigniez, Fanny, Durand, Noel, Mestres, Christian   +5 more
core   +1 more source

The validation of pharmacogenetics for the identification of Fabry patients to be treated with migalastat [PDF]

, 2017
PURPOSE: Fabry disease is an X-linked lysosomal storage disorder caused by mutations in the α-galactosidase A gene. Migalastat, a pharmacological chaperone, binds to specific mutant forms of α-galactosidase A to restore lysosomal activity.
A Gal, AK Topaloglu, Benjamin Bronfin, C Filoni, Carrolee Barlow, CM Eng, Daniel G. Bichet, David J. Lockhart, Derralynn Hughes, Dominique P. Germain, DP Germain, DP Germain, DP Germain, DP Germain, E Conzelmann, Elfrida R. Benjamin, ER Benjamin, Evan Katz, Farhana Pruthi, FK Johnson, G Altarescu, GH Yam, GH Yam, Hadis Williams, J Lukas, J Shabbeer, Jay Barth, Jeff Castelli, John Kirk, JQ Fan, Julie Yu, Kenneth J. Valenzano, L Barisoni, L Echevarria, M Ries, Maria Cecilia Della Valle, MJ van Breemen, P Lemansky, R Giugliani, R Khanna, Raphael Schiffmann, RJ Desnick, RJ Desnick, RO Brady, Robert J. Desnick, Roberto Giugliani, S Ishii, Sarah Bond, SH Shin, SM Rombach, William R. Wilcox, WR Wilcox, X Wu, Xiaoyang Wu   +53 more
core   +1 more source

Biochemical properties of digestive carbohydrases from the sugar beet weevil, Lixus incanescens (Coleoptera: Curculionidae) [PDF]

Arthropods, 2013
The sugar beet weevil, Lixus incanescens B., is one of the most important pests of sugar beet plant in Iran. The petioles and leaves of sugar beet are attacked by larvae and adults of the sugar beet weevil.
Seyed Mohammad Ahsaei, Vahid Hosseininaveh, Mahdieh Bigham   +2 more
doaj  

Anderson-Fabry disease: a multiorgan disease. [PDF]

, 2013
Fabry disease (FD) is a rare X-linked lysosomal storage disorder caused by a deficiency of the enzyme α-galactosidase A . FD causes glycolipids, such as globotriaosylceramide (Gb3), to accumulate in the vascular endothelium of several organs (fig.2 ...
Antonino Tuttolomondo, Antonio Pinto, Giuseppe Licata, Irene Simonetta, Rosaria Pecoraro, Salvatore Miceli   +5 more
core   +1 more source

Isolation and Identification of an α-Galactosidase-Producing Lactosphaera pasteurii Strain and Its Enzymatic Expression Analysis

Molecules, 2022
α-Galactosidase (EC 3.2.1.22) refers to a group of enzymes that hydrolyze oligosaccharides containing α-galactoside-banded glycosides, such as stachyose, raffinose, and verbascose.
Yan Zhao, Jinghui Zhou, Shan Dai, Xiaozhu Liu, Xuewen Zhang   +4 more
doaj   +1 more source

Genetically Modified Cell Transplantation Through Macroencapsulated Spheroids with Scaffolds to Treat Fabry Disease

Cell Transplantation, 2021
Cell transplantation is expected to be another strategy to treat lysosomal diseases, having several advantages compared to enzyme replacement therapy, such as continuous enzyme secretion and one-time treatment to cure diseases.
Daisuke Kami, Yosuke Suzuki, Masashi Yamanami, Takahiro Tsukimura, Tadayasu Togawa, Hitoshi Sakuraba, Satoshi Gojo   +6 more
doaj   +1 more source

A classical phenotype of Anderson-Fabry disease in a female patient with intronic mutations of the GLA gene: a case report [PDF]

, 2012
Background: Fabry disease (FD) is a hereditary metabolic disorder caused by the partial or total inactivation of a lysosomal hydrolase, the enzyme α-galactosidase A (GLA). This inactivation is responsible for the storage of undegraded glycosphingolipids
Albeggiani, G, ALESSANDRO, Riccardo, COLOMBA, Paolo, Duro, G., Iemolo, F, Imbraco, M, Pisani, A, Zizzo, Carmela   +7 more
core   +2 more sources

A Novel Mutation in The GLA Gene Leading to Fabry Disease - A Case Report from Islamabad, Pakistan

Life and Science
Fabry disease (OMIM #301500) is a rare X-linked lysosomal storage disease. Generally, lysosomal storage disease is identified by inappropriate lipid storage in lysosomes due to specific enzyme deficiencies.
Ayesha Ali Malick, Muhammad Jawad Hassan, Arsalan Ahmad   +2 more
doaj   +1 more source

Purification and characterization of an alpha-galactosidase from Aspergillus fumigatus

Brazilian Archives of Biology and Technology, 2005
Aspergillus fumigatus secreted invertase (beta-fructofuranosidase) and alpha-galactosidase enzymatic activities able to hydrolyzing raffinose oligosaccharides (RO).
Sebastião Tavares de Rezende, Valéria Monteze Guimarães, Marília de Castro Rodrigues, Carlos Roberto Felix   +3 more
doaj   +1 more source