Results 241 to 250 of about 286,880 (314)

Role of feed forward neural networks coupled with genetic algorithm in capitalizing of intracellular alpha-galactosidase production by Acinetobacter sp. [PDF]

Biomed Res Int, 2014
Edupuganti S, Potumarthi R, Sathish T, Mangamoori LN.   +3 more
europepmc   +1 more source

Correction: Globotriaosylsphingosine Accumulation and Not Alpha-Galactosidase-A Deficiency Causes Endothelial Dysfunction in Fabry Disease

PLoS ONE, 2012
Mehdi Namdar, Catherine Gebhard, Rafael Studiger, Yi Shi, Pavani Mocharla, Christian Schmied, Pedro Brugada, Thomas F. Lüscher, Giovanni G. Camici   +8 more
openaire   +2 more sources

IAP Antagonists Selectively Eliminate Therapy‐Induced Senescent Cancer Cells via TNFα‐Independent Apoptosis

Cancer Science, Volume 117, Issue 4, Page 1043-1056, April 2026.
Upon chemotherapy, a subset of cancer cells enters a senescent state, referred to as TIS. When IAP antagonists are administered, TIS cells are selectively eliminated through TNFα‐independent apoptosis. TNFα secreted by TIS cancer cells may also act in a paracrine manner to enhance extrinsic apoptosis in neighboring non‐senescent cancer cells.
Hiroaki Ochiiwa, Takeshi Wakasa, Yuki Kataoka, Koji Ando, Eiji Oki, Yoshihiko Maehara, Makoto Iimori, Hiroyuki Kitao   +7 more
wiley   +1 more source

Cryptogenic stroke and small fiber neuropathy of unknown etiology in patients with alpha-galactosidase A -10T genotype. [PDF]

Orphanet J Rare Dis, 2014
Schelleckes M, Lenders M, Guske K, Schmitz B, Tanislav C, Ständer S, Metze D, Katona I, Weis J, Brand SM, Duning T, Brand E.   +11 more
europepmc   +1 more source

OMICS Profiling Identifies Signatures of Senescence in Osteogenesis Imperfecta Osteoblasts Counteracted by 4‐PBA

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Mutations in collagen I are the most common cause of osteogenesis imperfecta (OI), leading to delayed protein folding and structurally abnormal molecules. While some aberrant collagen is secreted into the extracellular matrix (ECM), impairing bone quality, a significant fraction is retained intracellularly, disrupting osteoblast homeostasis. 4‐
Roberta Besio, Elisa Maffioli, Erika Palladino, Alessandra Sala, Nadia Garibaldi, Valerio Izzi, Antonella Forlino, Gabriella Tedeschi   +7 more
wiley   +1 more source

Capsaicin Receptor TRPV1 Delays Aortic Aging in Atherosclerotic Mice by Inhibiting the ISG15‐p53 Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 8, April 2026.
ABSTRACT Vascular aging constitutes a significant pathological basis for the aging of various organs and systems within the human body. This study employed a murine model of atherosclerosis (AS) and Transient Receptor Potential Vanilloid 1 (TRPV1)‐deficient AS mice to ascertain whether TRPV1 exerts an influence on AS by modulating aortic aging ...
Duo Zhang, Jishuang Liu, Te Liu, Jiulin Chen, ZhiHua Yu, Yun Gu, Fangfang Dou   +6 more
wiley   +1 more source

First Detection of Lactococcus formosensis subsp. formosensis in Rainbow Trout (Oncorhynchus mykiss) in Europe

Journal of Fish Diseases, Volume 49, Issue 4, April 2026.
ABSTRACT Lactococcus garvieae, Lactococcus petauri and Lactococcus formosensis are etiological agents of piscine lactococcosis, a disease reported in Italy since the early 1990s and linked to significant aquaculture losses. To the best of our knowledge, this study reports the first detection of L. formosensis subsp. formosensis in farmed rainbow trout (
Silvia Colussi, Giuseppe Esposito, Khalid Shahin, Pier Luigi Acutis, Lucio Fariano, Claudio Ghittino, Maria Goria, Fabio Bondavalli, Paolo Ajmone Marsan, Giorgia Bignami, Elena Bozzetta, Marino Prearo, Paolo Pastorino   +12 more
wiley   +1 more source

From Shoulder to Heart: Acute Shoulder Pain Leads to a Diagnosis of Fabry Disease. [PDF]

JACC Case Rep
Kalaria A, Farooq W, Kolupoti A, Meng J, Kim AS.   +4 more
europepmc   +1 more source

GeARF5/GeIAA33‐GeSWEET14 module balances the secondary metabolic biosynthesis to increase the yield and quality in Gastrodia elata

Journal of Integrative Plant Biology, Volume 68, Issue 4, Page 1155-1175, April 2026.
Auxin signaling regulates the formation of vegetative propagation corms in Gastrodia elata by regulating sugar‐acid interconversion, which in turn regulates polysaccharide and starch biosynthesis as well as biosynthesis of the bioactive metabolite gastrodin.
Qun Liu, Zhiqing Wu, Yugang Gao, Yue Xu, Pu Zang, Xinyu Yang, Yan Zhao, Pan Liao, Benoît Boachon, Guoyin Kai   +9 more
wiley   +1 more source

Persistent troponin elevation in the heart of Fabry disease due to coronary microvascular dysfunction. [PDF]

SAGE Open Med Case Rep
Tan C, Higgins MD, Zhang Z, Hiskens M.
europepmc   +1 more source