Results 41 to 50 of about 2,093 (106)

Genetics of Common Obesity in Children and Adolescents

Annals of the New York Academy of Sciences, Volume 1553, Issue 1, Page 34-49, November 2025.
Abstract Childhood obesity is a multifactorial public health problem worldwide. Genetic variation influences the predisposition to develop obesity at early stages of life. Childhood obesity may be classified as syndromic, monogenic, or polygenic depending on the genetic component.
Guadalupe León‐Reyes, Francisco J. López Alavez, Maria Elizabeth Tejero   +2 more
wiley   +1 more source

Heart Regeneration and Repair: Molecular Mechanism and Therapeutic Targets

MedComm, Volume 6, Issue 10, October 2025.
Regarding the general picture of heart regeneration therapy, it encompasses exogenous cell therapy, endogenous medications, metabolism, interventions in gene pathways, as well as the therapeutic strategies in the burgeoning interdisciplinary field of medicine and engineering in recent years.
Mingchuan Liu, Tingwei Peng, Rui Yu, Kexin Wang, Di Wang, Xiaojie Jia, Yan Zhang, Jianqiang Hu, Bingchao Qi, Yan Li   +9 more
wiley   +1 more source

Examining the association between the FTO gene and neuroticism reveals indirect effects on subjective well-being and problematic alcohol use

Scientific Reports
Associations between the fat mass and obesity-associated (FTO) gene and obesity are well-established. However, recent studies have linked FTO to addiction phenotypes and dopaminergic signaling, thus suggesting broader psychiatric implications.
Wenjie Cai, Yvonne Forsell, Catharina Lavebratt, Philippe A. Melas   +3 more
doaj   +1 more source

Established and Emerging Roles of Epigenetic Regulation in Diabetic Cardiomyopathy

Diabetes/Metabolism Research and Reviews, Volume 41, Issue 6, September 2025.
ABSTRACT An increasing number of individuals are at high risk of type 2 diabetes (T2DM) and its cardiovascular (CV) complications, which challenges healthcare systems with an increased risk of developing CV diseases. Patients with T2DM exhibit a unique cardiac phenotype termed diabetic cardiomyopathy (DCM).
Adam Russell‐Hallinan, Narainrit Karuna, Frank Lezoualc'h, Giuseppe Matullo, Hana Baker, Monique Bernard, Yvan Devaux, Lina Badimon, Gemma Vilahur, Jennifer Rieusset, Geneviève A. Derumeaux, Chris J. Watson   +11 more
wiley   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Alpha-Ketoglutarate-Dependent Dioxygenase FTO [PDF]

, 2020
openaire   +1 more source

Metabolic oxidoreductases: central regulators of the epigenetic landscapes in stemness. [PDF]

Exp Mol Med
Lee HT, Roe JS, Youn HD.
europepmc   +1 more source

Dysregulation of ERAD and Stress Response Proteins by V493F FTO Over-expression: A Proteomic Perspective. [PDF]

In Vivo
Kanli A.
europepmc   +1 more source

m⁶A RNA Methylation Is Increased in Tumour Invasive Regions and Influences Invasive Capability and Chemotherapeutic Sensitivity in Adult Glioblastoma. [PDF]

Int J Mol Sci
Radhi M, Rowlinson J, Walker L, Deacon S, Knight HM, Smith S.   +5 more
europepmc   +1 more source

FTO in cardiovascular diseases: mechanisms, context dependence, and translational opportunities. [PDF]

Front Cell Dev Biol
Kong Y, Zhang D.
europepmc   +1 more source