Results 181 to 190 of about 10,436 (217)

Alpha-MSH peptides inhibit acute inflammation and contact sensitivity

Peptides, 1990
Alpha-melanocyte stimulating hormone [alpha-MSH(1-13)] occurs within the CNS, skin, circulation and in other body sites. This tridecapeptide and its COOH-terminal tripeptide, alpha-MSH (11-13), have antipyretic and anti-inflammatory actions. Studies of the anti-inflammatory effects of these molecules have been confined mainly to tests of inhibition of ...
M E, Hiltz, J M, Lipton
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Alpha-MSH regulates protein ubiquitination in T cells.

Cellular and molecular biology (Noisy-le-Grand, France), 2006
The neuropeptide alpha-melanocyte stimulating hormone (alpha-MSH) suppresses IFN-gamma + T cells from mice. We discovered, however, that despite this significant production by DTH-mediating effector CD4 supression of IFN-gamma production, alpha-MSH-treated effector T cells had the same level of IFN-gamma mRNA expression and intracellular IFN-gamma ...
D J, Biros, K, Namba, A W, Taylor
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Alpha MSH-induced excessive grooming behavior involves a GABAergic mechanism

Peptides, 1991
It has been shown that MSH administered in the ventral tegmental area (VTA) elicits excessive grooming behavior (EGB) by stimulating an acetylcholinergic pathway. The present work was performed in order to evaluate the possible participation of the GABAergic system in this behavior. VTA injection of GABA antagonist bicuculline stimulated the EGB (55.5 +
S R, De Barioglio, N, Lezcano, M E, Celis   +2 more
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alpha-MSH and desacetyl-alpha-MSH signaling through melanocortin receptors.

Annals of the New York Academy of Sciences, 2003
The functional significance of N-terminal acetylation of ACTH[1-13]NH(2) is unknown. N-terminal acetylation of ACTH[1-13]NH(2) (known as desacetyl-alpha-MSH) to produce alpha-MSH enhances some activities of ACTH[1-13]NH(2) and virtually eliminates others.
Kathleen G, Mountjoy, Chia-Shan Jenny, Wu, Jillian, Cornish, Karen E, Callon   +3 more
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Des-acetyl-alpha-MSH and not alpha-MSH is the major form of alpha-MSH in amniotic fluid.

Journal of endocrinological investigation, 1988
Immunoreactive alpha-melanocyte stimulating hormone (IR-alpha-MSH)-like activity was measured by radioimmunoassay (RIA) in at term pregnancy amniotic fluid prior and after adsorption on a Sep-pak C18 cartridge. alpha-MSH activity was 3-4 times lower after Sep-pak purification but, unlike the levels of IR-alpha-MSH in the fluid analyzed in toto ...
A, Mauri, A, Argiolas, M R, Melis, L, Lai, W, Fratta, A, Caruso, A, Lanzone, F, Serri, F, Caminiti, S, Mancuso   +9 more
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[Alpha-MSH and pregnancy].

Zeitschrift fur Hautkrankheiten, 1989
In 32 pregnant women, we repeatedly determined the levels of alpha-MSH, melatonin, ACTH and progesterone. In the radioimmunoassay, all of these hormones showed a significant increase from the first to the third trimester. In contrast to progesterone, neither the level of alpha-MSH nor that of melatonin rises significantly until between the 28th and ...
P, Altmeyer, A, Bernd, H, Holzmann, M, Bacharach-Buhles, E, Halberstadt   +4 more
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The neuroimmunomodulatory peptide alpha-MSH.

Annals of the New York Academy of Sciences, 2001
Alpha-melanocyte-stimulating hormone (alpha-MSH), a neuroimmunomodulatory peptide of ancient origin, is known to be involved in the control of host responses. In inflammatory cells, in the periphery and within the central nervous system, alpha-MSH modulates the production and action of proinflammatory cytokines.
T, Ichiyama, S, Sato, K, Okada, A, Catania, J M, Lipton   +4 more
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The neuropeptide alpha-MSH in host defense.

Annals of the New York Academy of Sciences, 2000
The presence of the ancient peptide alpha-melanocyte-stimulating hormone (alpha-MSH) in barrier organs such as gut and skin suggests that this potent anti-inflammatory molecule may be a component of the innate host defense. In tests of antimicrobial activities, alpha-MSH and its fragment KPV showed inhibitory influences against the gram-positive ...
A. Catania, M. Cutuli, L. Garofalo, A. Carlin, L. Airaghi, W. Barcellini, J. M. Lipton   +6 more
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Central alpha-MSH, energy balance, thermal balance, and antipyresis

Journal of Thermal Biology, 2010
Abstract Intracerebroventricular administration of alpha-MSH in young adult rats enhanced metabolic rate and caused a dose-dependent suppression of food intake, exhibiting a coordinated catabolic pattern. However, the thermoregulatory effects did not seem to be coordinated: the rising heat production was accompanied by a practically simultaneous ...
M. Balaskó, A. Garami, S. Soós, M. Koncsecskó-Gáspár, M. Székely, E. Pétervári   +5 more
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Age-related alterations in the central thermoregulatory responsiveness to alpha-MSH

Journal of Thermal Biology, 2015
Alpha-melanocyte-stimulating-hormone (alpha-MSH) is a neuropeptide that induces weight loss via its anorexigenic and hypermetabolic/hyperthermic effects. Two major public health problems of the human population involving energy balance (i.e. middle-aged obesity and aging cachexia) also appear in other mammals, therefore age-related regulatory ...
I, Rostás, N, Füredi, J, Tenk, A, Mikó, M, Solymár, S, Soós, M, Székely, E, Pétervári, M, Balaskó   +8 more
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