Results 31 to 40 of about 10,436 (217)

Alpha-Melanocyte Stimulating Hormone Protects against Cytokine-Induced Barrier Damage in Caco-2 Intestinal Epithelial Monolayers. [PDF]

open access: yesPLoS ONE, 2017
Alpha-melanocyte-stimulating hormone (α-MSH) is a potent anti-inflammatory peptide with cytoprotective effect in various tissues. The present investigation demonstrates the ability of α-MSH to interact with intestinal epithelial cell monolayers and ...
Judit Váradi   +13 more
doaj   +1 more source

Cypress tree (Chamaecyparis obtusa) Bark extract inhibits melanogenesis through repressing CREB and MITF signalling pathways in α-MSH-stimulated B16F10 cells

open access: yesFood and Agricultural Immunology, 2022
Cypress tree (Chamaecyparis obtusa) bark is well-known for its bio-functional activities and high content of polyphenol and flavonoids. It has previously exhibited antioxidant, anti-pathogenic, and anti-inflammatory activities.
Al Borhan Bayazid   +3 more
doaj   +1 more source

The melanocortin receptors and their accessory proteins. [PDF]

open access: yes, 2013
The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Chan, LF   +3 more
core   +2 more sources

The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients [PDF]

open access: yes, 2020
Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many of these drugs is the voltage-gated sodium channel (VGSC).
Falciani, Francesco   +4 more
core   +1 more source

Extracellular Soluble Membranes from Retinal Pigment Epithelial Cells Mediate Apoptosis in Macrophages

open access: yesCells, 2021
A central characterization of retinal immunobiology is the prevention of proinflammatory activity by macrophages. The retinal pigment epithelial cells (RPEs) are a major source of soluble anti-inflammatory factors.
Nayan Sanjiv   +4 more
doaj   +1 more source

The Alpha-Melanocyte Stimulating Hormone Induces Conversion of Effector T Cells into Treg Cells

open access: yesJournal of Transplantation, 2011
The neuropeptide alpha-melanocyte stimulating hormone (α-MSH) has an important role in modulating immunity and homeostasis. The production of IFN-γ by effector T cells is suppressed by α-MSH, while TGF-β production is promoted in the same cells.
Andrew W. Taylor, Darren J. Lee
doaj   +1 more source

α‐Melanocyte‐stimulating hormone inhibition of oxytocin neurons switches to excitation in late pregnancy and lactation

open access: yesPhysiological Reports, 2022
Oxytocin is secreted into the periphery by magnocellular neurons of the hypothalamic supraoptic and paraventricular nuclei (SON and PVN) to trigger uterine contraction during birth and milk ejection during suckling.
Michael R. Perkinson   +5 more
doaj   +1 more source

Discriminating Children with Speech Sound Disorders from Children with Typically Developing Speech Using the Motor Speech Hierarchy Probe Words: A Preliminary Analysis of Mandibular Control. [PDF]

open access: yesDiagnostics (Basel)
Background/Objectives: The Motor Speech Hierarchy (MSH) Probe Words (PWs) have yet to be validated as effective in discriminating between children with impaired and children with typically developing speech motor control.
Orton L   +6 more
europepmc   +2 more sources

Sargahydroquinoic Acid Suppresses Hyperpigmentation by cAMP and ERK1/2-Mediated Downregulation of MITF in α-MSH-Stimulated B16F10 Cells

open access: yesFoods, 2021
Hyperpigmentation diseases of the skin require topical treatment with depigmenting agents. We investigated the hypopigmented mechanisms of sargahydroquinoic acid (SHQA) in alpha-melanocyte-stimulating hormone (α-MSH)-stimulated B16F10 cells. SHQA reduced
Mohammed Shariful Azam   +5 more
doaj   +1 more source

Melanocortin signalling in fat cells [PDF]

open access: yes, 2009
[resumo]Melanocortin peptides and their receptors have long been known to affect the central control of food intake and body weight, thus playing a critical role in the development of obesity [1].
Almeida, Henrique   +2 more
core  

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