Results 61 to 70 of about 10,436 (217)

The Value of Technetium-99m Labeled Alpha-Melanocyte- Stimulating Hormone (99mTc-α-MSH) in Diagnosis of Primary and Metastatic Lesions of Malignant Melanoma [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2018
Objective(s): Malignant melanoma is the most lethal type of skincancers with unfavorable prognosis. Alpha-MSH peptide analogues havea high affinity for melanocortine-1 (MC1) receptors on melanocytes overexpressing in malignant melanoma cells.
Saeed Farzanefar, Rahman Etemadi, Mohammad Shirkhoda, Habibollah Mahmoodzadeh, Mostafa Erfani, Babak Fallahi, Mehrshad Abbasi, Narjess Ayati, Arman Hassanzadeh-Rad, Mohammad Eftekhari, Davood Beiki   +10 more
doaj   +1 more source

Autoimmune and autoinflammatory mechanisms in uveitis [PDF]

, 2014
The eye, as currently viewed, is neither immunologically ignorant nor sequestered from the systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve tissue and cellular function in the face of immune-mediated insult ...
A Amadi-Obi, A Arida, A Cortes, A Fox, A Jager, A Peters, A Rothova, AC Anderson, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AD Dick, AG Commodaro, AG Commodaro, AJ St. Leger, AK Denniston, AK Denniston, AL Oberg, Andrew D. Dick, B Bodaghi, B Engelhardt, BJ Raveney, BJ Raveney, BJ Raveney, BS Sheridan, C Broderick, C Terrada, C-C Chan, CC Murphy, CEI Janssen, Chi-Chao Chan, CJ Calder, CJ Chu, CJ Chu, D Atan, D Atan, D Atan, D Atan, D Banerjee, D Luger, D Perra, DA Carter, DA Copland, DA Copland, DA Copland, DA Copland, DA Jabs, DC Wraith, DF Martin, DJ Hankey, DJ Kilmartin, DL Turner, E Furusato, EB Gouveia, EC Kerr, EC Kerr, ED Mandelcorn, EF Foxman, EF Remmers, EJ Wherry, F An, F Chen, G Geri, GJ Wright, GJ Wright, GR Wallace, H Keino, H Mielants, H. Nida Sen, HL Rosenzweig, HL Rosenzweig, HL Rosenzweig, HM Cherwinski, HN Sen, IJ Crane, J Bauer, J Candia, J Chen, J Correale, JA Todd, JB Fordham, JC Wei, JF Bach, JJ Kuiper, JP Sherlock, JT Rosenbaum, JV Forrester, JV Forrester, JV Forrester, JV Forrester, K Gocho, KG Anderson, KH Sonoda, KM Murphy, KM Murphy, L Jostins, L Mao, Lai Wei, Lindsay B. Nicholson, LK Grange, LK Mackay, LM Wakim, LM Wakim, LP Schewitz, LV Rizzo, M Chen, M Cordero-Coma, M Deckert, M Greter, M Khairallah, M Pepper, MC Jenmalm, MG Netea, MJ Mattapallil, MJ Robertson, MS Suttorp-Schulten, N Hashida, N Mizuki, N Taylor, N Yosef, NA Rao, O Tomkins-Netzer, P Kivisäkk, P Yang, P Zamiri, PA Kurz, PB Medawar, PP Sfikakis, R Banchereau, R Gold, R Plumlee Courtney, R Ramesh, R Shechter, R Zhang, R Zhou, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, RB Nussenblatt, Richard W. Lee, RJ Snelgrove, RK Agarwal, RM Hoek, Robert B. Nussenblatt, RP Nair, RR Caspi, RR Caspi, RR Caspi, RR Caspi, RW Darrell, RW Lee, RW Lee, RW Lee, RW Read, RW Read, S Horie, S Hou, S Hou, S Jawad, S Ohno, S Ooka, S Preston, S Sugita, S Sugita, S Sugita, S Sugita, S Yeh, S Zhang, SA Ramsey, SB Su, SC Bendall, SC Teoh, SJ Morrison, SL Masters, SM Islam, SM Sharma, SM Whitcup, SR Boyd, SR Taylor, SR Thurau, SR Thurau, SW McPherson, T Lambe, T Yoshimura, TA Manolio, TM Martin, U Kaufmann, VL Calder, W Chi, W Chi, WF Hickey, WW Soon, Y Fei, Y Kirino, Y Okunuki, Y Peng, Y Usui, YH Lee, Z Li, Z Tu   +203 more
core   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Anti-melanogenesis effect from Wampee fruit pectin via α-MSH/TRY pathway in A375 cells

BMC Complementary Medicine and Therapies, 2022
Background Polysaccharides from wampee have been reported to process various biological activities, while the relationship between structure and bioactivities has been barely addressed.
Weiyu Fu, Xuehua Liao, Qian Zhang, Yuzhen Zhu, Si Mei, Qian Li, Xin Zhou, Xiaojun Li, Hui Luo, Hua Ye, Kefeng Wu   +10 more
doaj   +1 more source

Antiinflammatory influences of alpha-MSH molecules: central neurogenic and peripheral actions [PDF]

The Journal of Neuroscience, 1994
alpha-Melanocyte-stimulating hormone (alpha-MSH1–13) and its COOH- terminal tripeptide alpha-MSH11–13 (Lys Pro Val) inhibit inflammation when administered systemically. Recent evidence indicates that alpha- MSH1–13 can likewise inhibit inflammation in the skin solely via an action within the brain.
A, Macaluso, D, McCoy, G, Ceriani, T, Watanabe, J, Biltz, A, Catania, J M, Lipton   +6 more
openaire   +2 more sources

PEARL: Protein Eluting Alginate with Recombinant Lactobacilli

Small, EarlyView.
Probiotic lactobacilli meet engineered living materials: This study introduces PEARL (protein eluting alginate with recombinant lactobacilli), an innovative engineered living material combining Lactiplantibacillus plantarum and alginate beads for controlled protein release.
Varun Sai Tadimarri, Marc Blanch‐Asensio, Ketaki Deshpande, Jonas Baumann, Carole Baumann, Rolf Müller, Sara Trujillo, Shrikrishnan Sankaran   +7 more
wiley   +1 more source

Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance

, 2009
OBJECTIVE: The hypothalamic control of energy balance is regulated by a complex network of neuropeptide-releasing neurons. Whilst the effect of these neuropeptides on individual aspects of energy homeostasis has been studied, the coordinated response of ...
AC Linthorst, AD Howard, AJ Dunn, AM Wren, AP Goldstone, AS Chen, C Broberger, C Fekete, C Fekete, C J Small, CB Lawrence, CJ Billington, CK Song, CM Edwards, CR Abbott, CR Abbott, D Huszar, D J L Gunner, D Qu, EC Griffiths, GL de, GS Yeo, J Le Magnen, J Le Magnen, J R C Parkinson, JE Morley, JH Strubbe, JJ Hagan, JM Vaughan, JT Clark, K G Murphy, K Hashimoto, K L Smith, KG Mountjoy, KL Smith, L Negri, M A Ghatei, M Egawa, M Egawa, M Harris, M Monda, M Rossi, M Rossi, M Yokota, MM Ollmann, MM Wirth, MS Kim, MS Kim, N M Semjonous, NJ Spiteri, R Hanada, R Poggioli, S R Bloom, S Schuhler, T Hanada, T Sakurai, Y-L Liu   +56 more
core   +1 more source

Minocycline Modulation of Alpha-MSH Production by Keratinocytes In vitro

Acta Dermato-Venereologica, 1999
The anti-inflammatory mechanisms of minocycline, an antibiotic used in the treatment of the inflammatory component of acne, are only partially understood. In addition to inflammation due to cytokines (IL-1, IL-6, TNF-alpha, etc.), recent studies have shown that neuropeptide-mediated neurogenic inflammation may play an important role in cutaneous ...
I, Sainte-Marie, I, Tenaud, O, Jumbou, B, Dréno   +3 more
openaire   +3 more sources

Validation of the City Birth Trauma Scale in a sample of Norwegian mothers

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
The Norwegian City Birth Trauma Scale (City BiTS‐Nor) demonstrated strong psychometric properties in a sample of 1079 mothers. A bifactor structure and high reliability support its use for assessing childbirth‐related PTSD symptoms. Findings highlight its clinical utility for screening and guiding targeted interventions in perinatal mental health care.
Silje Marie Haga, Luisa Bergunde, Lara Seefeld, Susan Ayers, Malin Eberhard‐Gran, Susan Garthus‐Niegel   +5 more
wiley   +1 more source

Single administration of tripeptide alpha-MSH(11-13) attenuates brain damage by reduced inflammation and apoptosis after experimental traumatic brain injury in mice [PDF]

, 2013
Following traumatic brain injury (TBI) neuroinflammatory processes promote neuronal cell loss. Alpha-melanocyte-stimulating hormone (alpha-MSH) is a neuropeptide with immunomodulatory properties, which may offer neuroprotection.
Engelhard, Kristin, Jahn-Eimermacher, Antje, Kornes, Frida, Luh, Clara, Pieter, Dana, Schaible, Eva-Verena, Schäfer, Michael, Sebastiani, Anne, Steinsträßer, Arne, Thal, Serge   +9 more
core   +1 more source