Results 61 to 70 of about 8,293 (202)

Preschool Duration, Family Background and Long‐Term Outcomes: Evidence From the Expansion of École Maternelle in France

Oxford Bulletin of Economics and Statistics, EarlyView.
ABSTRACT This paper analyses the long‐term effects of preschool education in France. We focus on the effect of preschool duration on educational attainment and labour market earnings in adulthood. Building on an old tradition of free and universal pre‐primary education, France implemented in the late 1960s a large‐scale expansion of preschooling ...
Francesco Andreoli, Arnaud Lefranc, Vincenzo Prete   +2 more
wiley   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Keratinocytes exposed to ultraviolet A and ultraviolet B radiation induce responses in melanocytes

Photochemistry and Photobiology, EarlyView.
Keratinocyte‐derived soluble factors regulate melanocyte responses following UV exposure. Conditioned medium from irradiated keratinocytes enhances melanocyte mitochondrial activity, cell proliferation, and cell cycle progression while improving survival after UVA‐induced damage.
Lais Zortéa, Andressa Mai Matsumoto, Alessandra Costa Lopes, Eduardo Felipe Wagner, Tanira da Silveira Prieto, Andrés Delgado Cañedo, Daza de Moraes Vaz Batista Filgueira, Ana Paula de Souza Votto   +7 more
wiley   +1 more source

Glutathione Trisulphide Improves Skin Brightness with Anti-Melanogenesis Effects and Maintains Intracellular Persulphide Levels

Cosmetics
Melanin, the principal component of skin pigmentation, is produced through tyrosinase activity. Recently, supersulphides have been identified in human cells and found to play a role in maintaining cellular activities.
Yoshiaki Uchida, Toshiya Sato
doaj   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Excited‐State Antiaromaticity in Nonbenzenoid Aromatics: Examining the Dynamics of Intramolecular Proton Transfer With a Small Driving Force

Angewandte Chemie, Volume 138, Issue 33, 10 August 2026.
The excited‐state antiaromaticity of hydroxybenzotropyliums (HBTs) can be tuned through substituent effects to bring the aromatic ‘enol’ (E) and keto (K) tautomers close in energy. This leads to abnormally slow excited‐state proton transfer (on the ns timescale), giving rise to dual fluorescence emission and weak photoacidity.
Promeet K. Saha, Charlotte A. Bardsley, Hector G. Miranda‐Salinas, Daniel Crane, Rabia Ayub, Andrew P. Monkman, Paul R. McGonigal   +6 more
wiley   +2 more sources

Identification of Crucial Drug Targets and Pathways to Reprogram Drug Resistance Through Epigenetic Modulation in Advanced Lung Cancer Using Integrated Bioinformatics Approach

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman, Mossammat Rima Akter, Nur Alam   +2 more
wiley   +1 more source

Assessing Clinical Severity and Prognosis in Adolescents With Anorexia Nervosa and Atypical Anorexia Nervosa Using the Albumin‐Globulin Ratio

European Eating Disorders Review, Volume 34, Issue 5, Page 1193-1208, September 2026.
ABSTRACT Objective The albumin‐globulin ratio (AGR) is a biochemical marker reflecting nutritional and inflammatory status, with significant prognostic value in chronic conditions. This study examined its association with clinical/biochemical markers in adolescents with anorexia nervosa (AN) and atypical AN (AAN).
Eylem Şerife Kalkan, Ayşe Bilge Baklaci, Yelda Kiliç, Sinem Akgül, Nilgün Özgül, Melis Pehlivanturk Kizilkan   +5 more
wiley   +1 more source

The Importance of Melanocortin Receptors and Their Agonists in Pulmonary Disease

Frontiers in Medicine, 2019
Melanocortin agonists are ancient neuropeptides that have steroidogenesis and anti-inflammatory properties. They activate melanocortin receptors (MCR), a family of five seven-transmembrane G-protein coupled receptors. MC1R and MC3R are mainly involved in
Anna Elizabeth Moscowitz, Huda Asif, Laurence Baily Lindenmaier, Andrew Calzadilla, Chongxu Zhang, Mehdi Mirsaeidi, Mehdi Mirsaeidi   +6 more
doaj   +1 more source

Alexithymia in Anorexia Nervosa, More State Than Trait? A Multi‐Dimensional Assessment of Emotion Processing in Patients With Anorexia Nervosa, Recovered Patients and Healthy Controls

European Eating Disorders Review, Volume 34, Issue 5, Page 1402-1411, September 2026.
ABSTRACT Objective Alexithymia is implicated in both development and maintenance of Anorexia Nervosa (AN). It is unclear what defines alexithymia in AN. In this study, emotion processing related to alexithymia was examined. Method 40 patients with AN, 43 recovered (RC) patients and 35 matched healthy controls (HC) filled out questionnaires on eating ...
E. Wezenberg, S. K. Peters, A. A. van Elburg, S. H. W. Mares   +3 more
wiley   +1 more source