Results 1 to 10 of about 1,060,115 (160)

Desacetyl-α-MSH and α-MSH have sex specific interactions with diet to influence mouse gut morphology, metabolites and microbiota. [PDF]

Sci Rep, 2020
The melanocortin peptides have an important role in regulating body weight and appetite. Mice that lack the desacetyl-α-MSH and α-MSH peptides (Pomctm1/tm1) develop obesity. This effect is exacerbated by a high fat diet (HFD).
Sun B, Vatanen T, Jayasinghe TN, McKenzie E, Murphy R, O'Sullivan JM.   +5 more
europepmc   +2 more sources

Long-Term Dynamics of Serum α-MSH and α-MSH-Binding Immunoglobulins with a Link to Gut Microbiota Composition in Patients with Anorexia Nervosa.

Neuroendocrinology
International audienceINTRODUCTION: Immunoglobulins (Ig) reactive with α-melanocyte-stimulating hormone (α-MSH), an anorexigenic neuropeptide, are present in humans and were previously associated with eating disorders.
Seitz J, Lahaye E, Andreani NA, Thomas B, Takhlidjt S, Chartrel N, Herpertz-Dahlmann B, Baines JF, Fetissov SO.   +8 more
europepmc   +2 more sources

α-MSH analogue attenuates blood pressure elevation in DOCA-salt hypertensive mice. [PDF]

, 2013
Melanocyte-stimulating hormones, α-, β- and γ-MSH, regulate important physiological functions including energy homeostasis, inflammation and sodium metabolism.
Eriika Savontaus (145909), Petteri Rinne, Wendy Nordlund, Anna-Maija Penttinen, Anna-Maija Penttinen (282524), Eriika Savontaus, Petteri Rinne (446978), Markku Ahotupa (446980), Wendy Nordlund (446979), Markku Ahotupa, Ahotupa Markku, Rinne Petteri, Penttinen Anna-Maija, Nordlund Wendy, Savontaus Eriika   +14 more
core   +1 more source

α-Melanocyte-stimulating-hormone (α-MSH) modulates human chondrocyte activation induced by proinflammatory cytokines [PDF]

, 2015
BACKGROUND: Alpha-melanocyte-stimulating-hormone (α-MSH) has marked anti-inflammatory potential. Proinflammatory cytokines are critical mediators of the disturbed cartilage homeostasis in osteoarthritis, inhibiting anabolic activities and increasing ...
C. Lonati, R. Accetta, A. Catania, A. Ongari, S. Gatti, F. Capsoni   +5 more
core   +1 more source

Immunohistochemical staining and analysis of NF-κB activation in cytokine- and α-MSH-treated Caco-2 cells.

, 2017
(5A) Caco-2 cells were treated for 30 minutes with culture medium (C), cytokines (CK; 50 ng/ml TNF-α and 25 ng/ml IL-1β), or cytokines and 10−8 M α-MSH (CK+MSH). Nuclear localization of the NF-κB p65 subunit was monitored by immunostaining.
András Harazin (3567704), David Haines (3684631), Péter Gogolák (2609569), Gábor Vasvári (3684628), Katalin Réti-Nagy (507443), Ferenc Fenyvesi (507442), Mária A. Deli (323777), Ildikó Bácskay (507453), Miklós Vecsernyés (507452), Zoltán Ujhelyi (507450), Pálma Fehér (507451), Judit Váradi (507449), György Vámosi (3684625), Eszter Róka (3684634)   +13 more
core   +1 more source

Disappearance and excretion of labeled α-MSH in man

, 1978
Despite the considerable evidence for the CNS actions of α-melanocyte-stimulating hormone (α-MSH) in man, little attention has been given to its half-time disappearance from plasma and urinary excretion in normal individuals.
Redding, Tommie W, Coy, David H, Kastin, Abba J, Schally, Andrew V, Nikolics, Karoly   +4 more
core   +1 more source

In vitro assays of ¹¹¹In-labeled 3-arm DOTA-α-MSH (■) and 4-arm DOTA-α-MSH (●) in B16-F1 melanoma cells.

, 2019
111In-labeled 4-arm DOTA-α-MSH was taken up early into B16-F1 cells and showed higher accumulation than 111In-labeled 3-arm DOTA-α-MSH after 10 min of incubation. **P P 111In-labeled 3-arm DOTA-α-MSH and 4-arm DOTA-α-MSH.
Toshitaka Kato (6316901), Kodai Nishi (3984584), Keiichi Kawai (297179), Masaaki Ihara (6499319), Ryuichi Nishii (416886), Asuka Mizutani (6499322), Kohshin Washiyama (384442), Leo G. Flores 2nd (6499325), Masato Kobayashi (423651)   +8 more
core   +1 more source

Peripherally administered desacetyl α-MSH and α-MSH both influence postnatal rat growth and associated rat hypothalamic protein expression

, 2006
Desacetyl α-MSH predominates over α-MSH during development, but whether it is biologically active and has a physiological role is unclear. We compared the effects of 0.3 μg·g -1·day -1 desacetyl α-MSH with that of 0.3 μg·g -1·day -1 α-MSH on postnatal ...
Cooper, Garth J S, Wu, Chia Shan Jenny, Mountjoy, Kathleen G., Jensen, Dwayne J., Tatnell, Michele A., Greenwood, David R., Cooney, Janine M.   +6 more
core   +1 more source

α-MSH Influences the Excitability of Feeding-Related Neurons in the Hypothalamus and Dorsal Vagal Complex of Rats [PDF]

, 2017
Alpha-melanocyte-stimulating hormone (α-MSH) is processed from proopiomelanocortin (POMC) and acts on the melanocortin receptors, MC3 and MC4. α-MSH plays a key role in energy homeostasis.
Zheng-Yao Jiang, Hong-Zai Guan, Xi Chen, Jing Dong   +3 more
core   +1 more source

FIV-α-MSH transduction of HEK293T cells: characterization at the DNA, mRNA and protein levels. A

, 2012
. Genomic DNA extracted either before (293T) or 24 and 72 h after transduction of HEK293T cells with FIV-α-MSH (293T-α-MSH) was analyzed by PCR using the recombinant α-MSH-specific primers. The plasmid pLionII- α -MSH was used to demonstrate the expected
Miriam Friedman-Einat (165278), Sara Yosefi (165264), Gideon Hen (165262), Sivan Mygdal (165271), Dmitry Shinder (165267), Reba Condiotti (165272), Adi Or (165269), Amir Bor (165275), Dalit Sela-Donenfeld (165276), Eithan Galun (20636)   +9 more
core   +1 more source