Results 41 to 50 of about 1,060,115 (160)
Soluble versus surface bound α-MSH.
, 2016 Effect of immobilized α-MSH (EO7-MHS) on LPS induced endothelial IL-6 production compared to cells re-plated onto culture dishes in culture medium containing either no soluble α-MSH (Control) or soluble α-MSH in concentration ranging from 0.2 nM to 10 μM.
Laurent Plawinski (2253649) +5 more
core +1 more source
Systemic RVX‐208 Attenuates Experimental Periodontitis Through Inflammatory Host Modulation
Journal of Periodontal Research, EarlyView.Prophylactic systemic treatment with RVX‐208 mitigated alveolar bone loss in experimental periodontitis. In THP‐1 cells, transcriptomic analysis showed that RVX‐208 downregulated inflammatory gene expression associated with Pg, and it produced a more moderate and limited effect on global gene expression than the pan‐BET inhibitor JQ1.
Sheikh Alam +12 more
wiley +1 more source
The Effect of α MSH Analogues on Rat Bones
, 2002 Melanocortin is the downstream mediator of leptin signaling and absence of leptin signaling in ob/ob and db/db mice revealed the enhancement of bone formation through the central regulation.
육종인, 이유미
core +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Keratinocytes exposed to ultraviolet A and ultraviolet B radiation induce responses in melanocytes
Photochemistry and Photobiology, EarlyView.Keratinocyte‐derived soluble factors regulate melanocyte responses following UV exposure. Conditioned medium from irradiated keratinocytes enhances melanocyte mitochondrial activity, cell proliferation, and cell cycle progression while improving survival after UVA‐induced damage.
Lais Zortéa +7 more
wiley +1 more source
The α-MSH – SARCOIDOSIS path and other closely related concepts.
, 2014 The α-MSH – SARCOIDOSIS path and other closely related concepts.
Ruggero Gramatica (508116) +5 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Computational and Systems Oncology, Volume 6, Issue 1, December 2026.ABSTRACT Resistance to chemotherapy, which is demonstrated in almost every patient with advanced‐stage lung cancer (ALC), underscores an urgent need to unravel the underlying molecular mechanisms and identify novel strategies to overcome drug resistance. In the present study, an attempt was made to identify epigenetic targets and modulators that can be
Okibur Rahman +2 more
wiley +1 more source
, 2013 (A) Time course of weight change after an intraperitoneal (i.p.) injection of saline and NDP-α-MSH (0.3 mg/kg). The values are based on a change from pretreatment weight. n = 7 per group. (B) Dose-dependent effects of NDP-α-MSH on body weight.
Eriika Savontaus (145909) +4 more
core +1 more source
Protein Science, Volume 35, Issue 11, November 2026.Abstract Membrane‐embedded bacterial receptors are challenging to express and purify in soluble form, yet their isolated domains are essential tools for structural and ligand‐discovery studies. Pseudomonas aeruginosa relies on the TonB‐dependent heme receptor HasR for iron acquisition, a process central to its pathogenicity.
Federico Bosetto +9 more
wiley +1 more source