Synthesis of Terpineol from Alpha-Pinene Catalyzed by α-Hydroxy Acids [PDF]
Molecules, 2022 We report the use of five alpha-hydroxy acids (citric, tartaric, mandelic, lactic and glycolic acids) as catalysts in the synthesis of terpineol from alpha-pinene.
Zhong-Lei Meng +5 more
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Alpha-pinene moderates memory impairment induced by kainic acid via improving the BDNF/TrkB/CREB signaling pathway in rat hippocampus [PDF]
Frontiers in Molecular Neuroscience, 2023 IntroductionThe potential benefits of natural ingredients in the alleviation of neurodegenerative disorders are of great interest. Alpha-pinene (APN) is an essential oil belonging to monoterpenes with multiple beneficial effects.
Paria Hashemi, Shamseddin Ahmadi
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The effects of alpha‐pinene against paracetamol‐induced liver damage in male rats [PDF]
Physiological ReportsThis study aims to evaluate the hepatoprotective effect of alpha‐pinene against N‐acetyl‐p‐aminophenol, paracetamol, (APA)‐induced liver damage in rats. Thirty Wistar rats were divided into five groups (n = 6): Group 1: Normal (control). Group 2: APA 640
Kaveh Rahimi +4 more
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Alpha-pinene ameliorates liver fibrosis by suppressing oxidative stress, inflammation, and the TGF-β/Smad3 signaling pathway [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): A monoterpene alpha-pinene possesses anti-oxidant, anti-inflammatory, and anti-apoptotic properties. Here, we investigated the effect of alpha-pinene on molecular, biochemical, and histological changes induced by carbon tetrachloride (CCl4)
Fatemeh Noroozi +3 more
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Alpha-pinene ameliorate behavioral deficit induced by early postnatal hypoxia in the rat: study the inflammatory mechanism [PDF]
Scientific ReportsNeonatal hypoxia has a negative impact on the developing brain during the sensitive period. Inflammation plays a key role in the physiological response to hypoxic stress.
Sharareh Bakhtazad +3 more
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Alpha-pinene alleviates CCl4-induced renal and testicular injury in rats by targeting oxidative stress, inflammation, and apoptosis [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Renal and testicular disorders are primarily associated with oxidative damage and inflammation. Here, alpha-pinene (a type of monoterpene) was investigated for its effect on oxidative/nitrosative stress and the expression of inflammatory ...
Fatemeh Noroozi +3 more
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Neuroprotective effects of alpha-pinene against behavioral deficits in ketamine-induced mice model of schizophrenia: Focusing on oxidative stress status [PDF]
IBRO Neuroscience ReportsSchizophrenia (SCZ) is a profound neurological disorder that affects approximately 1% of the global population. Alpha-pinene (α-pinene) is a natural and active monoterpene found in coniferous tree oil, primarily pine, with diverse pharmacological ...
Akbar Hajizadeh Moghaddam +5 more
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Effects of super-class cannabis terpenes beta-caryophyllene and alpha-pinene on zebrafish behavioural biomarkers. [PDF]
Sci Rep, 2022 Terpenes possess a wide range of medicinal properties and are potential therapeutics for a variety of pathological conditions. This study investigated the acute effects of two cannabis terpenes, β-caryophyllene and α-pinene, on zebrafish locomotion ...
Johnson A +3 more
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Can Alpha-Pinene Prevent Methotrexate-Induced Cardiac and Hepatic Damage? [PDF]
Physiol ResThe effects of alpha-pinene (AP), a monoterpenoid, known for its antioxidant, anti-inflammatory, and anti-apoptotic properties, on methotrexate (MTX)-induced cardiac and hepatic damage were investigated in this study.
Cirrik S +4 more
europepmc +2 more sources
The effects of alpha-pinene on inflammatory responses and oxidative stress in the formalin test
Brain Research Bulletin, 2023 Alpha-pinene (α- pinene), an essential oil that falls under the category of monoterpenes, has various advantages. This research delves into the potential benefits of α-pinene in alleviating nociception caused by the formalin test and the molecular ...
Kaveh Rahimi +5 more
doaj +2 more sources