Results 171 to 180 of about 68,100 (329)

TRIM28 regulates the stability and toxicity of alpha-synuclein and tau through a common mechanism [PDF]

, 2015
Maxime W.C. Rousseaux, María de Haro, Cristian A. Lasagna‐Reeves, Antonia De Maio, Paymaan Jafar‐Nejad, J. Park, Ismael Al‐Ramahi, Rakez Kayed, H. Botas, Huda Y. Zoghbi   +9 more
openalex   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Ow949 Zgis125[P(Dat-1)::Alpha-Synuclein::Yfp] | 2014-04-14T09:36:05+02:00

, 2018
Céline N. Martineau, Ellen A. A. Nollen
openalex   +1 more source

Pathological Relevance of Post-translationally Modified Alpha-Synuclein (pSer87, pSer129, nTyr39) in Idiopathic Parkinson’s Disease and Multiple System Atrophy

, 2022
Berkiye Sonustun, Firat M Altay, Catherine Strand, Geshanthi Hondhamuni, Thomas T. Warner, Hilal A. Lashuel, Rina Bandopadhyay   +6 more
openalex   +2 more sources

Ow940 Zgis128[P(Dat-1)::Alpha-Synuclein::Yfp] | 2014-03-14T13:39:36+01:00

, 2018
Céline N. Martineau, Ellen A. A. Nollen
openalex   +1 more source

Prodromal Lewy Body Symptoms and α‐Synuclein Seeding in Idiopathic Olfactory Dysfunction

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Early identification of pathological α‐synuclein deposition (αSynD) may improve understanding of Lewy body disorder (LBD) progression and enable timely disease‐modifying treatments. Objectives We investigated αSynD using a seed amplification assay and assessed prodromal LBD symptoms in individuals with idiopathic olfactory ...
Oskar Hoffmann McWilliam, Remarh Bsoul, Gunhild Waldemar, Steen Gregers Hasselbalch, Anja Hvid Simonsen, Marie Bruun, Laura Storm Næsborg Andersen, Christian von Buchwald, Kasper Aanæs, Christian K. Pedersen, Ida S.B. Andersen, Magne Bech, Clara Hageman Pinborg, Aušrinė Areškevičiūtė, Eva Løbner Lund, Kristian Steen Frederiksen   +15 more
wiley   +1 more source

Ow949 Zgis125[P(Dat-1)::Alpha-Synuclein::Yfp] | 2014-03-01T14:36:34+01:00

, 2018
Céline N. Martineau, Ellen A. A. Nollen
openalex   +1 more source

Local cortical overexpression of human wild-type alpha-synuclein leads to increased dendritic spine density in mouse

, 2020
Lucia M. Wagner, Sheyna M. Nathwani, Patrick P. Ten Eyck, Georgina M. Aldridge   +3 more
openalex   +2 more sources

Soluble alpha-synuclein post-translational modifications: unexpected regulators of pathological alpha-synuclein amplification

Neural Regeneration Research, 2023
Simran Kapila, Yuhan Sun, Chao Peng, Shujing Zhang   +3 more
openaire   +2 more sources

Prognostic Value of Parkinson's Disease Subtypes in the LABS‐PD Cohort: Functional Ability, Quality of Life and Mortality

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Research on Parkinson's disease (PD) heterogeneity may inform clinical prognosis. There is currently no fully validated PD subtype classification system. Objectives We aimed at assessing the prognostic relevance of a data‐driven PD subtype classification system.
Deepa Dash, Shirley Eberly, David Oakes, David Grimes, Anthony E. Lang, Caroline Tanner, Tiago A. Mestre, Connie Marras   +7 more
wiley   +1 more source