Results 171 to 180 of about 659,948 (302)

Alpha-Synuclein Dynamics in Cerebral Ischemia. [PDF]

ASN Neuro
Bordbar S, Molavizade S, Dehghani F, Davoody S, Bahadori AR, Tafakhori A.   +5 more
europepmc   +1 more source

Co‐ and Multi‐Pathologies in Parkinson's Disease: An International Parkinson and Movement Disorder Society Scientific Issues Committee Review

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) has been historically defined as a disease of striatal dopamine deficiency secondary to degeneration of dopaminergic neurons in the substantia nigra pars compacta, related to the presence of Lewy bodies and Lewy neurites.
Michele Matarazzo, Per Borghammer, Inas Elsayed, Jennifer G. Goldman, Yue Huang, Katja Lohmann, Per Svenningsson, Lorraine V. Kalia, Daniela Berg, Jeffrey H. Kordower, the MDS Scientific Issues Committee   +10 more
wiley   +1 more source

The Ecology of Care in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Joaquin A. Vizcarra
wiley   +1 more source

Cutaneous Phosphorylated Alpha-Synuclein in Lewy Body Dementia. [PDF]

Ann Clin Transl Neurol
Gibbons CH, Levine T, Adler CH, Bellaire B, Wang N, Agarwal P, Aldridge GM, Barboi A, Claassen D, Evidente VGH, Galasko D, Gonzalez-Duarte A, Gil R, Gudesblatt M, Isaacson SH, Kaufmann H, Khemani P, Kumar R, Lamotte G, Liu AJ, McFarland NR, Miglis MG, Reynolds A, Sahagian GA, Saint-Hilaire MH, Schwartzbard JB, Singer W, Soileau MJ, Vernino S, Millar Vernetti P, Yerstein O, Freeman R.   +31 more
europepmc   +1 more source

A Brainstem Radiomics Framework to Distinguish Progressive Supranuclear Palsy from Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Differentiating progressive supranuclear palsy (PSP) from Parkinson's disease (PD) can be clinically challenging. In the neuroimaging field, radiomics has emerged as a promising approach to capture subtle microstructural and textural image alterations, improving differential diagnoses.
Chiara Camastra, Jolanda Buonocore, Antonio Augimeri, Camilla Calomino, Maria Giovanna Bianco, Alessia Sarica, Pier Paolo Arcuri, Aldo Quattrone, Andrea Quattrone   +8 more
wiley   +1 more source

A Systematic Comparison of Alpha-Synuclein Seed Amplification Assays for Increasing Reproducibility. [PDF]

Ann Clin Transl Neurol
Amaral-do-Nascimento M, Santos DF, Vieira TCRG, Outeiro TF.   +3 more
europepmc   +1 more source

Seeing Invisible Oligomers: Rethinking α‐Synuclein Pathology Through Proximity Ligation Assay

Movement Disorders, EarlyView.
Abstract Parkinson's disease (PD) and multiple system atrophy are defined by α‐synuclein (αSYN)‐positive inclusions – Lewy bodies (LBs) and glial cytoplasmic inclusions – yet mounting evidence indicates that these inclusions represent only a fraction of disease‐relevant pathology.
Hiroaki Sekiya, Nanna Møller Jensen, Dennis W. Dickson, Poul Henning Jensen   +3 more
wiley   +1 more source

A bibliometric analysis of alpha-synuclein in Parkinson's disease from 2015 to 2024. [PDF]

Front Neurol
Xiao L, Lin S, Wu Y, Liu X, Gu D, Fan J, Zhuang L.   +6 more
europepmc   +1 more source

Heterogenous Neuropathology in a Pedigree with RAB39B‐Related Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background In 2015, we reported a family with Parkinson's disease resulting from the RAB39B p.G192R (c.574G>A) variant. Since then, two affected brothers from the family have undergone autopsy. Objectives To characterize neuropathological findings, assess intracellular distribution of RAB39B protein, and examine the effect of p.G192R on α ...
Caitlin Latimer, Oswaldo Lorenzo‐Betancor, Dong‐Hui Chen, Kimmy Su, Marika Bogdani, Anna J. Park, Minsuh Kim, Joshua Weiss, Malia Callier, Ella H. Chiu, Sarah Fish, Jennifer L. Witt, Wendy H. Raskind, Marie Y. Davis, C. Dirk Keene, Cyrus P. Zabetian   +15 more
wiley   +1 more source

Alpha-synuclein co-pathology in a real-world early Alzheimer's disease cohort. [PDF]

Alzheimers Dement
Shiner T, Nathan T, Levy MH, David AB, Omer N, Awad AA, Ash E, Weisz MG, Goldstein O, Alcalay Y, Regev K, Lamoureux J, Van Keuren-Jensen K, Blauwendraat C, Alcalay RN, Bregman N.   +15 more
europepmc   +1 more source