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Applications of Artificial Intelligence in Thalassemia: A Comprehensive Review
Diagnostics, 2023 Thalassemia is an autosomal recessive genetic disorder that affects the beta or alpha subunits of the hemoglobin structure. Thalassemia is classified as a hypochromic microcytic anemia and a definitive diagnosis of thalassemia is made by genetic testing ...
Khaled Ferih +7 more
doaj +1 more source
Iraqi Journal of Hematology, 2021 BACKGROUND: Iron deficiency is not common in thalassemia minor and nontransfusion dependent hemoglobinophaties. The majority of these patients have normal-to-high serum ferritin. OBJECTIVES: The aims of the study were to evaluate serum ferritin levels in
Mehdi Dehghani +4 more
doaj +1 more source
Thalassemia and hemoglobinopathy prevalence in a community-based sample in Sylhet, Bangladesh
Orphanet Journal of Rare Diseases, 2023 Background Inherited blood disorders affect 7% of the population worldwide, with higher prevalences in countries in the “thalassemia belt,” which includes Bangladesh.
Amanda S. Wendt +5 more
doaj +1 more source
Association Between Thalassemia and Leucocytic DNA Damage: A Pilot Study
Journal of Basic and Applied Research in Biomedicine, 2022 Objectives: Thalassemia with frequent blood transfusion was considered under oxidative stress because of the chance of iron overload. Patients with thalassemia trait with no blood transfusion might also suffered from oxidative stress because of ...
Yim Szeto, Charlton CHAN
doaj +2 more sources
Alpha-thalassemia-X-linked intellectual disability syndrome
Definitions, 2020 Males with alpha thalassemia X-linked intellectual disability syndrome have intellectual disability and delayed development. Their speech is significantly delayed, and most never speak or sign more than a few words.
semanticscholar +1 more source
Newborn Screening Practices and Alpha-Thalassemia Detection — United States, 2016
MMWR. Morbidity and mortality weekly report, 2020 Alpha-thalassemia comprises a group of inherited disorders in which alpha-hemoglobin chain production is reduced. Depending on the genotype, alpha-thalassemia results in moderate to profound anemia, hemolysis, growth delays, splenomegaly, and increased ...
M. Bender +10 more
semanticscholar +1 more source
İstanbul Tıp Fakültesi Dergisi, 2021 Objective: Alpha thalassemia is a common type of hemoglobinopathy that occurs as a result of deletions or point mutations in the alpha globin gene cluster.
Selma Demir +5 more
doaj +1 more source
Alpha-thalassemia in two Mediterranean populations [PDF]
Blood, 1982 Abstract We used restriction endonuclease analysis to determine the incidence of alpha-thalassemia in two Mediterranean islands. In a random population sample, the gene frequency of deletion-type alpha-thalassemia-2 (- alpha) was 0.18 in Sardinians and 0.07 in Greek Cypriots. All cases were the rightward crossover type.
PIRASTU M +10 more
openaire +4 more sources
Alpha-Hemoglobin Stabilizing Protein Gene Polymorphism (rs4499252 A/G) and its Association with Beta-Thalassemia Major in Iraqi Patients [PDF]
Archives of Razi Institute, 2022 Beta thalassemia (β-thalassemia) major is a genetic disorder of hemoglobin production that results in a diminished rate of synthesis of one or more of the globin chains causing variable degrees of anemia.
M Adnan Khalaf +3 more
doaj +1 more source
Frequency and genotyping of alpha thalassemia in individuals undergoing premarital screening.
JPMA. The Journal of the Pakistan Medical Association, 2020 OBJECTIVE To evaluate the frequency of alpha thalassemia and detect mutations in the alpha genes in individuals undergoing premarital screening. METHODS The cross-sectional study was conducted at King Fahad Central Hospital, Jazan, Saudi Arabia, from ...
M. Saboor +6 more
semanticscholar +1 more source