Results 1 to 10 of about 45,771 (276)

A Phylogenetic Analysis of the Globins in Fungi [PDF]

PLoS ONE, 2012
BackgroundAll globins belong to one of three families: the F (flavohemoglobin) and S (sensor) families that exhibit the canonical 3/3 α-helical fold, and the T (truncated 3/3 fold) globins characterized by a shortened 2/2 α-helical fold.
David Hoogewijs, Sylvia Dewilde, Andy R Vierstraete   +2 more
exaly   +3 more sources

The emerging roles of somatic globins in cardiovascular redox biology and beyond

Redox Biology, 2013
The vertebrate globins are a group of hemoproteins with the intrinsic capacity to regulate gaseous ligands and redox signaling required for cardiovascular biology.
Adam C Straub
exaly   +4 more sources

Globins in the marine annelid Platynereis dumerilii shed new light on hemoglobin evolution in bilaterians

BMC Evolutionary Biology, 2020
Background How vascular systems and their respiratory pigments evolved is still debated. While many animals present a vascular system, hemoglobin exists as a blood pigment only in a few groups (vertebrates, annelids, a few arthropod and mollusk species).
Solène Song, Viktor Starunov, Xavier Bailly, Christine Ruta, Pierre Kerner, Annemiek J. M. Cornelissen, Guillaume Balavoine   +6 more
doaj   +2 more sources

Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion

Redox Biology, 2022
Background & aims: Hepatic stellate cells (HSCs) are the primary cell type in liver fibrosis, a significant global health care burden. Cytoglobin (CYGB), a globin family member expressed in HSCs, inhibits HSC activation and reduces collagen ...
Vu Ngoc Hieu, Le Thi Thanh Thuy, Hoang Hai, Ninh Quoc Dat, Dinh Viet Hoang, Ngo Vinh Hanh, Dong Minh Phuong, Truong Huu Hoang, Hitomi Sawai, Yoshitsugu Shiro, Misako Sato-Matsubara, Daisuke Oikawa, Fuminori Tokunaga, Katsutoshi Yoshizato, Norifumi Kawada   +14 more
doaj   +2 more sources

Determination of Ligand Pathways in Globins: Apolar Tunnels Versus Polar Gates [PDF]

Journal of Biological Chemistry, 2012
Background: O2 pathways in animal hemoglobins and myoglobins are controversial. Results: Ligands enter and exit sperm whale Mb and Cerebratulus lacteus Hb by completely different pathways.
Adams, Aranda, Berka, Bidon-Chanal, Birukou, Birukou, Bolognesi, Bossa, Bourgeois, Brunori, Carver, Daigle, Deng, Elber, Elber, Elber, Emsley, Germani, Golden, Hirota, Huang, Knapp, Lai, Laskowski, Lim, Lim, Liong, Milani, Milani, Mouawad, Nutt, Olson, Olson, Orlowski, Orlowski, Orlowski, Ouellet, Perutz, Pesce, Pesce, Pesce, Pflugrath, Quillin, Quillin, Ringe, Ruscio, Salter, Savard, Schmidt, Schoenborn, Schoenborn, Schoenborn, Schoenborn, Schotte, Schotte, Scott, Scott, Springer, Springer, Springer, Srajer, Teng, Tilton, Tilton, Vandergon   +64 more
core   +2 more sources

Electron transfer function versus oxygen delivery: a comparative study for several hexacoordinated globins across the animal kingdom. [PDF]

PLoS ONE, 2011
Caenorhabditis elegans globin GLB-26 (expressed from gene T22C1.2) has been studied in comparison with human neuroglobin (Ngb) and cytoglobin (Cygb) for its electron transfer properties. GLB-26 exhibits no reversible binding for O(2) and a relatively low
Laurent Kiger, Lesley Tilleman, Eva Geuens, David Hoogewijs, Christophe Lechauve, Luc Moens, Sylvia Dewilde, Michael C Marden   +7 more
doaj   +2 more sources

More than hemoglobin - the unexpected diversity of globins in vertebrate red blood cells

Physiological Reports, 2015
In many multicellular organisms, oxygen is transported by respiratory proteins, which are globins in vertebrates, between respiratory organs and tissues. In jawed vertebrates, eight globins are known which are expressed in a highly tissue‐specific manner.
Mikko Nikinmaa
exaly   +2 more sources

Neuroglobin and Cytoglobin in Mammalian Nervous Systems: About Distribution, Regulation, Function, and Some Open Questions [PDF]

Brain Sciences
Globins are a class of globular proteins that function in the transportation or storage of oxygen. They are critical for cellular metabolism. Notable examples include hemoglobin, which is found in red blood cells, and myoglobin, which is present in ...
Stefan Reuss
doaj   +2 more sources

Function and evolution of vertebrate globins

Acta Physiologica, 2014
T. Burmester, T. Hankeln
exaly   +2 more sources

Mammalian nerve globins in search of functions

IUBMB Life, 2014
Paolo Ascenzi, Stefano Gustincich, Maria Marino   +2 more
exaly   +2 more sources