Results 11 to 20 of about 8,559 (239)

A phylogenomic profile of globins [PDF]

BMC Evolutionary Biology, 2006
Background Globins occur in all three kingdoms of life: they can be classified into single-domain globins and chimeric globins. The latter comprise the flavohemoglobins with a C-terminal FAD-binding domain and the gene-regulating globin coupled sensors ...
Dewilde Sylvia, Gough Julian, Arredondo-Peter Raúl, Bailly Xavier, Hoogewijs David, Vinogradov Serge N, Moens Luc, Vanfleteren Jacques R   +7 more
doaj   +8 more sources

Globins in Caenorhabditis elegans

IUBMB Life, 2011
AbstractExtensive in silico search of the genome of Caenorhabditis elegans revealed the presence of 33 genes coding for globins that are all transcribed. These globins are very diverse in gene and protein structure and are localized in a variety of cells, mostly neurons. The large number of C.
Tilleman, L, Germani, F, De Henau, S, Geuens, E, Hoogewijs, D, Braeckman, B P, Vanfleteren, J R, Moens, L, Dewilde, S   +8 more
openaire   +6 more sources

The emerging roles of somatic globins in cardiovascular redox biology and beyond

Redox Biology, 2013
The vertebrate globins are a group of hemoproteins with the intrinsic capacity to regulate gaseous ligands and redox signaling required for cardiovascular biology.
Mizanur M. Rahaman, Adam C. Straub
doaj   +2 more sources

An Interplay of Gases: Oxygen and Hydrogen in Biological Systems

Oxygen
Produced by photosynthesis, oxygen (O2) is a fundamentally important gas in biological systems, playing roles as a terminal electron receptor in respiration and in host defence through the creation of reactive oxygen species (ROS).
Grace Russell, Jennifer May, John T. Hancock   +2 more
doaj   +2 more sources

The globin gene family of the cephalochordate amphioxus: implications for chordate globin evolution [PDF]

BMC Evolutionary Biology, 2010
Background The lancelet amphioxus (Cephalochordata) is a close relative of vertebrates and thus may enhance our understanding of vertebrate gene and genome evolution.
Marden Michael C, Kiger Laurent, Vinogradov Serge N, Panopoulou Georgia, Ebner Bettina, Burmester Thorsten, Hankeln Thomas   +6 more
doaj   +4 more sources

Comparison of Evolutionary Relationships between Branchiostoma floridae, Ciona intestinalis, and Homo sapiens Globins Provide Evidence of Gene Co-Option and Convergent Evolution. [PDF]

Int J Mol Sci, 2023
Globins have been studied as model proteins to elucidate the principles of protein evolution. This was achieved by understanding the relationship between amino acid sequence, three-dimensional structure, physicochemical properties, and physiological ...
Yano N, Minamoto T, Yamaguchi H, Goto T, Nishikata T.   +4 more
europepmc   +2 more sources

A Globin in the Nucleus! [PDF]

Journal of Biological Chemistry, 2003
Cytoglobin and neuroglobin are recently discovered members of the globin family. In situ hybridization localized neuroglobin mainly in brain and retina, while cytoglobin was expressed ubiquitously in all analyzed tissues. In the present study, polyclonal antibodies were raised against both proteins and the distribution of them was studied by ...
Geuens, Eva, Brouns, Inge, Flamez, Daisy, Dewilde, Sylvia, Timmermans, Jean-Pierre, Moens, Luc   +5 more
openaire   +3 more sources

Regulation of the Globin Genes [PDF]

Pediatric Research, 2002
The a- and b-globin gene clusters are subject to several levels of regulation. They are expressed exclusively in the erythroid cells, only during defined periods of development and in a perfectly tuned way, assuring, at any stage of ontogeny, a correct balance in the availability of a- and b-globin chains for hemoglobin assembling. Such a tight control
Cao A, MOI, PAOLO
openaire   +3 more sources

TMEM8 – a non-globin gene entrapped in the globin web [PDF]

Nucleic Acids Research, 2009
For more than 30 years it was believed that globin gene domains included only genes encoding globin chains. Here we show that in chickens, the domain of alpha-globin genes also harbor the non-globin gene TMEM8. It was relocated to the vicinity of the alpha-globin cluster due to inversion of an approximately 170-kb genomic fragment.
Philonenko, Elena S., Klochkov, Denis B., Borunova, Victoria V., Gavrilov, Alexey A., Razin, Sergey V., Iarovaia, Olga V.   +5 more
openaire   +2 more sources

Globin and Globin Gene Structure of the Nerve Myoglobin of Aphrodite aculeata [PDF]

Journal of Biological Chemistry, 1996
The globin of the nerve cord of the polychaete annelid Aphrodite aculeata was isolated and purified to homogeneity. The native molecule has a pI of 6.3 and acts as a dimer of two identical Mr 15, 644.5 polypeptide chains as determined by electrospray mass spectrometry.
Dewilde, Sylvia, Blaxter, Mark, van Hauwaert, Marie-Louise, Vanfleteren, Jacques, Esmans, Eddy L., Marden, Mike, Griffon, Nathalie, Moens, Luc   +7 more
openaire   +3 more sources