Results 31 to 40 of about 9,131 (243)

Isolation, characterization and immunolocalization of a globin-like antigen from Ostertagia ostertagi adults [PDF]

open access: yes, 1996
Western blot analysis using an anti-globin rabbit serum Rb94 revealed a major band of 17 kDa in extracts of Ostertagia ostertagi adults and 4th-stage larvae.
De Marez, Tine   +23 more
core   +1 more source

Genotypic-Phenotypic Correlations in Non-HbE β-Thalassemia Intermedia: A Geographic Systematic Review. [PDF]

open access: yesMol Genet Genomic Med
β‐Thalassemia intermedia exhibits distinct region‐specific molecular patterns shaped by three interacting genetic axes: β‐globin mutation severity, HbF‐inducing modifiers, and α‐globin gene dosage. Mediterranean populations are predominantly mutation‐driven, Middle Eastern populations rely on HbF compensation, and Asian populations are governed by ...
Fernando K, Perera S, Premawardhena A.
europepmc   +2 more sources

Differences in cattle globins [PDF]

open access: yesBiochemical Journal, 1965
1. Comparisons have been made between electrophoretic mobilities of the cattle haemoglobins, HbA, HbB, HbC, HbD and HbF, at pH8.9. The fastest was HbB, then came in decreasing order HbF, HbC, HbA and HbD. 2. Globins were prepared from the main fractions of the five haemoglobins by CM-cellulose chromatography and investigated by starch-gel ...
G, Efremov, M, Braend
openaire   +2 more sources

Adaptation of a Fluorogenic RNA to N1‐Methylpseudouridine Nucleoside Chemistry

open access: yesAngewandte Chemie, EarlyView.
Several green‐emitting fluorogenic RNA aptamers were evaluated following the replacement of every uridine by N1‐methylpseudouridine (mΨ). Because this modification impaired the function of most aptamers, a directed evolution strategy combining droplet microfluidics, bioinformatics, and rational design was used to identify an aptamer preserving its ...
Patrick P.A. Bertrand   +4 more
wiley   +2 more sources

Hemoglobin switching in mice carrying the Klf1Nan variant

open access: yesHaematologica, 2020
Haploinsufficiency for transcription factor KLF1 causes a variety of human erythroid phenotypes, such as the In(Lu) blood type, increased HbA2 levels, and hereditary persistence of fetal hemoglobin. Severe dominant congenital dyserythropoietic anemia IV
Anne Korporaal   +7 more
doaj   +1 more source

Bacterial phyla whose globins may share ancestry with fungal globins.

open access: yes, 2012
Bacterial phyla whose globins may share ancestry with fungal globins.
Serge N. Vinogradov (181327)   +4 more
core   +1 more source

The diversity of 2/2 (truncated) globins [PDF]

open access: yes, 2013
Small size globins that have been defined as 'truncated haemoglobins' or as '2/2 haemoglobins' have increasingly been discovered in microorganisms since the early 1990s.
A. Pesce   +11 more
core   +1 more source

Redox-Regulation of α-Globin in Vascular Physiology

open access: yesAntioxidants, 2022
Interest in the structure, function, and evolutionary relations of circulating and intracellular globins dates back more than 60 years to the first determination of the three-dimensional structure of these proteins.
Laurent Kiger   +7 more
doaj   +1 more source

Human globin ψB2is not a globin-related sequence [PDF]

open access: yesNucleic Acids Research, 1982
We have determined the complete nucleotide sequence of 3.4 kilobase pairs of DNA covering the region of the human beta globin gene cluster where a human globin-related sequence psi beta 2 was thought to lie (Fritsch, Lawn, and Maniatis (1980) Cell 19, 959-972).
S H, Shen, O, Smithies
openaire   +2 more sources

The Coup-TFII orphan nuclear receptor is an activator of the γ-globin gene

open access: yesHaematologica, 2020
The human fetal γ-globin gene is repressed in the adult stage through complex regulatory mechanisms involving transcription factors and epigenetic modifiers.
Cristina Fugazza   +15 more
doaj   +1 more source

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