Results 51 to 60 of about 8,559 (239)
Changes of globins expression in tongue sole, Cynoglossus semilaevis (Actinopterygii: Pleuronectiformes: Cynoglossidae) in response to short-term hypoxia [PDF]
Acta Ichthyologica et Piscatoria, 2011 Background. Fishes live in the aquatic systems which are first affected by low or temporally changing O2 availability. Under hypoxia, the fish possess varieties of mechanism to ensure the uptake of an adequate amount of O2.
S. Wang Z. +6 more
doaj +3 more sources
Computational and Structural Biotechnology Journal, 2022 Globins constitute an ancient superfamily of proteins, exhibiting enormous structural and functional diversity, as demonstrated by many heme-binding families and two non-heme binding families that were discovered in bacterial stressosome component RsbR ...
Theresa Schneider +4 more
doaj +1 more source
Expanding the Utility of Exome Sequencing in Preventive and Population Genetics
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Carrier screening is a long‐standing genetic testing process offered to at‐risk couples, with or without a family history, who might have pregnancies affected by an autosomal recessive (AR) or X‐linked (XL) disorder. A total of 276 unrelated individuals, initially referred for rare disorder screening by clinicians, were enrolled in this study ...
Charilaos Kostoulas +6 more
wiley +1 more source
Phylogeny of Echinoderm Hemoglobins. [PDF]
PLoS ONE, 2015 Recent genomic information has revealed that neuroglobin and cytoglobin are the two principal lineages of vertebrate hemoglobins, with the latter encompassing the familiar myoglobin and α-globin/β-globin tetramer hemoglobin, and several minor groups.
Ana B Christensen +9 more
doaj +1 more source
Redox Biology, 2022 Nitric oxide (NO) is a signal molecule and plays a critical role in the regulation of vascular tone, displays anti-platelet and anti-inflammatory properties.
Arnab Ghosh +8 more
doaj +1 more source
Gelling Properties of Globin-Succinylated Globin Conjugates.
NIPPON SHOKUHIN KOGYO GAKKAISHI, 1993 2種類のグロビン-サクシニル化グロビン複合体(CMHTとCUT)を調製し,各複合体のゲル特性について検討した.(1) CMHTはGの配合比率が高くなる程ゲル形成pHは中性の方へ拡大した.例えば, GとSGの配合率が3:7の場合,ゲル形成pHは2.0であったが,G:SG=9:1の場合,ゲルはpH 2.0～3.5の範囲で形成された.一方, G:SGの配合比率が7:3と9:1のCUTの場合,ゲル形成pHは極めて狭い範囲に限定された.(2) ゲルの透明度はCMHT, CUTともにより酸性側で高く,また,グロビンの配合比率が高くなる程透明度も高くなる傾向を示した.(3) 複合体ゲルのゲル強度を測定した. CMHTの場合, G:SG=5:5 (pH 2.0)で高いゲル強度が得られた.
MIYAGUCHI, Yuji +4 more
openaire +2 more sources
Structural alignment of globins, phycocyanins and colicin A
, 1993 A database search employing a novel algorithm for protein structure comparison by alignment of distance matrices has revealed a striking resemblance between the tertiary structures of the bacterial toxin colicin A and globins.
Sander, Chris +3 more
core +1 more source
Discovery of CRBN‐based molecular glue degraders targeting WIZ transcription factor
Bulletin of the Korean Chemical Society, EarlyView.This work reports the discovery of 9l, a novel cereblon‐based molecular glue degrader which targets the WIZ transcription factor. Compound 9l facilitates WIZ‐CRBN ternary complex formation to degrade WIZ, subsequently inducing γ‐globin expression in HUDEP‐2 cells and highlighting its potential as a sickle cell disease therapy.
Tae‐Jun Kim +8 more
wiley +1 more source
Comparison of MLPA Method for Detection of Known and Unknown Deletions in Beta Globin Gene Cluster with Old Methods (REAL-TIME, RFLP, Gap-PCR) [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2009 Background and ObjectivesThalassaemia is one of the most common single gene disorders, which is most prevalent in the Mediterranean, the Middle East, Indian subcontinent (malaria belt).
R. Alimohammadi +10 more
doaj
Structure and haem-distal site plasticity in Methanosarcina acetivorans protoglobin. [PDF]
PLoS ONE, 2013 Protoglobin from Methanosarcina acetivorans C2A (MaPgb), a strictly anaerobic methanogenic Archaea, is a dimeric haem-protein whose biological role is still unknown.
Alessandra Pesce +11 more
doaj +1 more source