Results 71 to 80 of about 9,131 (243)

Neuroglobin and cytoglobin: two new members of globin family

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2011
The globin family has long been defined by myoglobin and hemoglobin, proteins with the functions of oxygen storage and transportation, respectively. Recently, two new members of this family were discovered: neuroglobin present in neurons and retinal ...
Priscilla Tosqui   +1 more
doaj   +1 more source

Iron metabolic pathways in the processes of sponge plasticity.

open access: yesPLoS ONE, 2020
The ability to regulate oxygen consumption evolved in ancestral animals and is intrinsically linked to iron metabolism. The iron pathways have been intensively studied in mammals, whereas data on distant invertebrates are limited.
Alexander D Finoshin   +11 more
doaj   +1 more source

Genetic and Clinical Characteristics of Thalassemia Trait and Construction of LASSO‐Based Model for Its Differentiating From Iron Deficiency Anemia in Northern China

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study revealed a β‐thalassemia‐trait‐dominated genetic spectrum in Northern‐Chinese patients with microcytic hypochromic anemia, with _αSEA/αα, HBB:c.316_197C>T and HBB:c.124_127delTTCT being the most prevalent α‐ and β‐globin genotypes. Using LASSO regression, we constructed a nomogram based on four routine complete‐blood‐count parameters (RBC ...
Wen‐jie Yu   +6 more
wiley   +1 more source

Monodisperse 130 kDa and 260 kDa Recombinant Human Hemoglobin Polymers as Scaffolds for Protein Engineering of Hemoglobin-Based Oxygen Carriers

open access: yesJournal of Functional Biomaterials, 2012
A recombinant 130 kDa dihemoglobin which is made up of a single-chain tetra-α globin and four β globins has been expressed as a soluble protein in E. coli. The sequence of the single chain tetra-α is: αI-Gly-αII-(SerGlyGly)5Ser-αIII-Gly-αIV.
Jacqueline F. Aitken   +6 more
doaj   +1 more source

MRI Proton Density Fat Fraction as a Biomarker of Marrow Recovery Following Organ‐Sparing Total Marrow Irradiation in Sickle Cell Disease

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Noninvasive quantitative assessment of marrow recovery after curative therapies such as total marrow irradiation (TMI) and bone marrow transplantation (BMT) remain poorly defined, particularly in sickle cell disease (SCD). Purpose To evaluate MRI‐derived proton density fat fraction (PDFF) as a biomarker of marrow recovery following ...
Malakeh Malekzadeh   +12 more
wiley   +1 more source

Ueber die Bildung des Leucinimids bei der peptischen und tryptischen Verdauung des Oxyhämoglobins resp. des Globins

open access: yes, 1901
UEBER DIE BILDUNG DES LEUCINIMIDS BEI DER PEPTISCHEN UND TRYPTISCHEN VERDAUUNG DES OXYHÄMOGLOBINS RESP. DES GLOBINS Details: Zeitschrift für physiologische Chemie: 1.1877-20.1895 Hoppe-Seyler's Zeitschrift für physiologische Chemie: 21.1895- 112.1921 (
Salaskin, S.
core   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij   +11 more
wiley   +1 more source

Alignment of the myristoylated globins GLB-26, GLB-26G2A, Globin X, and CmaenasHb.

open access: yes, 2013
The myristoylation sites of all globins, and the predicted NLS of GLB-26 are indicated.
Bart P. Braeckman (294301)   +11 more
core   +1 more source

Neuroglobina: nuevo miembro de la familia de las globinas Neuroglobin: a novel member of the globin family

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2011
Durante mucho tiempo se asumió que la hemoglobina y la mioglobina eran las únicas globinas de los vertebrados. En el año 2000 se descubrió un tercer tipo de globina, que sobre la base de su ubicación preferencial en el sistema nervioso fue denominada ...
Mariela Forrellat Barrios   +1 more
doaj  

A membrane-bound vertebrate globin.

open access: yesPLoS ONE, 2011
The family of vertebrate globins includes hemoglobin, myoglobin, and other O(2)-binding proteins of yet unclear functions. Among these, globin X is restricted to fish and amphibians.
Miriam Blank   +8 more
doaj   +1 more source

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