Results 21 to 30 of about 8,559 (239)

Cotranslational Folding of Globin [PDF]

Journal of Biological Chemistry, 1997
Globin synthesis in a wheat germ cell-free translation system was performed in the presence of [3H]hemin and [35S]methionine to determine the minimal length of the nascent ribosome-bound globin chain capable of heme binding. Nascent polypeptides of predetermined size were synthesized on ribosomes by translation of truncated mRNA molecules.
A A, Komar, A, Kommer, I A, Krasheninnikov, A S, Spirin   +3 more
openaire   +2 more sources

Lessons from the post-genomic era: Globin diversity beyond oxygen binding and transport

Redox Biology, 2020
Vertebrate hemoglobin (Hb) and myoglobin (Mb) were among the first proteins whose structures and sequences were determined over 50 years ago. In the subsequent pregenomic period, numerous related proteins came to light in plants, invertebrates and ...
Anna Keppner, Darko Maric, Miguel Correia, Teng Wei Koay, Ilaria M.C. Orlando, Serge N. Vinogradov, David Hoogewijs   +6 more
doaj   +1 more source

Challenges in the Diagnosis of Beta-thalassemia Syndrome: The Importance of Molecular Diagnosis

Oman Medical Journal, 2022
Patients with heterozygous β-thalassemia are generally asymptomatic. However, the intermediate phenotype is uncommon, and patients require further investigation to confirm the diagnosis.
Zefarina Zulkafli, Mohd Nazri Hassan, Shafini Mohd Yusoff, Noor Haslina Mohd Noor, Suryati Hussin, Nor Khairina Mohamed Kamarudin, Yuslina Mat Yusoff, Rosnah Bahar   +7 more
doaj   +1 more source

Nitric Oxide Trickle Drives Heme into Hemoglobin and Muscle Myoglobin

Cells, 2022
Ever since the days of NO being proclaimed as the “molecule of the year”, the molecular effects of this miracle gas on the globins have remained elusive.
Mamta P. Sumi, Blair Tupta, Arnab Ghosh
doaj   +1 more source

The folding pathway for globins [PDF]

FEBS Letters, 1977
Previous investigations have successfully predicted the three-dimensional structures of trypsin inhibitor [ 1,2] , myoglobin [3,4] , TMV protein [ 51 and rubredoxin [2]. Using mechanisms of protein chain folding which one of us [5 $1 suggested,.we can find a common folding pathway for the globins which are included in the ‘Atlas of Protein Sequence and
Lim, V.I., Efimov, A.V.
openaire   +2 more sources

Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family

BMC Genomics, 2007
Background The emergence of high throughput genome sequencing facilities and powerful high performance bioinformatic tools has highlighted hitherto unexpected wide occurrence of globins in the three kingdoms of life. In silico analysis of the genome of C.
Vinogradov Serge, Moens Luc, Vierstraete Andy, Dewilde Sylvia, Geuens Eva, Hoogewijs David, Vanfleteren Jacques R   +6 more
doaj   +1 more source

Capacity of extracellular globins to reduce liver fibrosis via scavenging reactive oxygen species and promoting MMP-1 secretion

Redox Biology, 2022
Background & aims: Hepatic stellate cells (HSCs) are the primary cell type in liver fibrosis, a significant global health care burden. Cytoglobin (CYGB), a globin family member expressed in HSCs, inhibits HSC activation and reduces collagen ...
Vu Ngoc Hieu, Le Thi Thanh Thuy, Hoang Hai, Ninh Quoc Dat, Dinh Viet Hoang, Ngo Vinh Hanh, Dong Minh Phuong, Truong Huu Hoang, Hitomi Sawai, Yoshitsugu Shiro, Misako Sato-Matsubara, Daisuke Oikawa, Fuminori Tokunaga, Katsutoshi Yoshizato, Norifumi Kawada   +14 more
doaj   +1 more source

Isolation, characterization and immunolocalization of a globin-like antigen from Ostertagia ostertagi adults [PDF]

, 1996
Western blot analysis using an anti-globin rabbit serum Rb94 revealed a major band of 17 kDa in extracts of Ostertagia ostertagi adults and 4th-stage larvae.
De Marez, Tine, Blaxter, Mark L, Berghen, Paul, Raes, Stefaan, Blaxter, M. L., de Marez, T. M., Berghen, P., de Marez, T.M., Vercruysse, J., de Graaf, Dirk, Raes, S., Vercruysse, Jozef, Moens, L., de Graaf, D.C., Moens, Luc, Blaxter, M.L., de Graaf, D. C.   +16 more
core   +1 more source

Transfusão de plaquetas: do empirismo ao embasamento científico Platelet transfusion: from empiricism to scientific evidence

Revista Brasileira de Hematologia e Hemoterapia, 2010
Despite major advances in Brazilian blood transfusion therapy with a growing number of scientific publications, an increased number of repeat donors and a decline in serological ineligibility, a lack of conformity in the application of pre-transfusion ...
Aline A. Ferreira, Sheila Soares, Vagner de Castro, Helio Moraes-Souza   +3 more
doaj   +1 more source

Bacterial and archaeal globins — A revised perspective [PDF]

, 2013
A bioinformatics survey of putative globins in over 2200 bacterial and some 140 archaeal genomes revealed that over half the bacterial and approximately one fifth of archaeal genomes contain genes encoding globins that were classified into three families:
Tinajero-Trejo, M, Poole, R K, Hoogewijs, D, Vinogradov, S N   +3 more
core   +1 more source