Results 21 to 30 of about 45,771 (276)
Neuroprotective effect of neuroglobin in hypoxia/ischemia
Neuroglobin is a representative of the globin group, an oxygen-binding protein which is predominantly expressed in the nervous system. Despite the large amount of conducted research, its role is still poorly understood.
E. V. Uzlova, S. M. Zimatkin
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Modulating Nitric Oxide Dioxygenase and Nitrite Reductase of Cytoglobin through Point Mutations
Cytoglobin is a hexacoordinate hemoglobin with physiological roles that are not clearly understood. Previously proposed physiological functions include nitric oxide regulation, oxygen sensing, or/and protection against oxidative stress under hypoxic ...
John Ukeri +2 more
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A phylogenomic profile of globins
Background Globins occur in all three kingdoms of life: they can be classified into single-domain globins and chimeric globins. The latter comprise the flavohemoglobins with a C-terminal FAD-binding domain and the gene-regulating globin coupled sensors ...
Dewilde Sylvia +7 more
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Lessons from the post-genomic era: Globin diversity beyond oxygen binding and transport
Vertebrate hemoglobin (Hb) and myoglobin (Mb) were among the first proteins whose structures and sequences were determined over 50 years ago. In the subsequent pregenomic period, numerous related proteins came to light in plants, invertebrates and ...
Anna Keppner +6 more
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Challenges in the Diagnosis of Beta-thalassemia Syndrome: The Importance of Molecular Diagnosis
Patients with heterozygous β-thalassemia are generally asymptomatic. However, the intermediate phenotype is uncommon, and patients require further investigation to confirm the diagnosis.
Zefarina Zulkafli +7 more
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Visible Volume: a Robust Measure for Protein Structure Characterization [PDF]
We propose a new characterization of protein structure based on the natural tetrahedral geometry of the β carbon and a new geometric measure of structural similarity, called visible volume.
Bashford +31 more
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Nitrosative stress defences of the enterohepatic pathogenic bacterium Helicobacter pullorum [PDF]
Helicobacter pullorum is an avian bacterium that causes gastroenteritis, intestinal bowel and hepatobiliary diseases in humans. Although H. pullorum has been shown to activate the mammalian innate immunity with release of nitric oxide (NO), the proteins ...
Boneca, Ivo G. +6 more
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Nitric Oxide Trickle Drives Heme into Hemoglobin and Muscle Myoglobin
Ever since the days of NO being proclaimed as the “molecule of the year”, the molecular effects of this miracle gas on the globins have remained elusive.
Mamta P. Sumi, Blair Tupta, Arnab Ghosh
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Number of Pages: 2Integrative BiologyGeological ...
Etchberger, Cory R., Iverson, John B.
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Background The emergence of high throughput genome sequencing facilities and powerful high performance bioinformatic tools has highlighted hitherto unexpected wide occurrence of globins in the three kingdoms of life. In silico analysis of the genome of C.
Vinogradov Serge +6 more
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