Results 91 to 100 of about 4,669,562 (299)

An Approach to Nuclear Fusion Utilizing the Dynamics of High-Density Electrons and Neutrals, Part I

open access: yesPlasma
An approach to achieve nuclear fusion utilizing the formation of high densities of electrons and neutrals is described. The abundance of low energy free electrons produces intense electric fields that reduce the Coulomb barrier in nuclear fusion ...
Alfred YiuFai Wong, Chun-Ching Shih
doaj   +1 more source

How Public Is the Internet? A Conversation on the Nature of Human Interactions On-line and the Implications for Research Methods [PDF]

open access: yes, 2008
In the past decade, ???virtual??? research???empirical investigations conducted via the Internet???has increased dramatically across a variety of disparate disciplines.
DeLap, Alpha Selene, Edwards, Phillip M.
core  

Fake Alpha

open access: yes, 2017
Why do investors entrust active mutual fund managers with large sums of money while receiving negative excess returns on average? Our explanation is that investors have a coarser information set than fund managers which leads them to systematically misinterpret managers' skill.
Müller, Marcel   +2 more
openaire   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Complete mitochondrial genome and phylogenetic analysis of Luciogobius parvulus (Synder, 1909) (Teleostei, Gobiidae) from Korea

open access: yesMitochondrial DNA. Part B. Resources
Luciogobius parvulus (Snyder, 1909) is distributed in restricted areas of Japan and South Korea. Here, we report the first complete mitochondrial genome of this species.
Min-Soo Kim   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Nutritional treatment in patients with cardiovascular diseases, hepatic steatosis and metabolic disorders

open access: yesMìžnarodnij Endokrinologìčnij Žurnal
Background. Cardiovascular diseases remain the leading cause of death in both men and women in ­industrialized countries. They encompass a variety of conditions, including cerebrovascular disease, peripheral arterial disease, atherosclerosis, and deep ...
Fidel Krasniqi   +2 more
doaj   +1 more source

Detecting and Quantifying Mind Wandering during Simulated Driving

open access: yesFrontiers in Human Neuroscience, 2017
Mind wandering is a pervasive threat to transportation safety, potentially accounting for a substantial number of crashes and fatalities. In the current study, mind wandering was induced through completion of the same task for 5 days, consisting of a 20 ...
Carryl L. Baldwin   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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