Results 91 to 100 of about 2,783,808 (253)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Midwestern AKA members, n.d.

open access: yes, 1995
AKA members from the Midwest hosted by WSU's BKΩ and Epsilon Alpha chapters at a gathering in Wichita.Archival master image scanned in reflective mode as 48-bit RGB color TIFF using Epson 11000 XL.
Alpha Kappa Alpha
core  

1198 Cytokine affinity tuning and antibody discovery/optimization using the AlphaSeq and AlphaBind platforms to generate targeted immuno-oncology therapeutics

open access: yesJournal for ImmunoTherapy of Cancer, 2023
Ryan Swanson   +11 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Alpha Sigma Alpha Scrapbook, 1992 [PDF]

open access: yes, 1992
https://digitalcommons.longwood.edu/alpha-sigma-alpha_scrapbooks/1007/thumbnail ...
Longwood University, Alpha Sigma Alpha
core  

Complete mitochondrial genome and phylogenetic analysis of Luciogobius parvulus (Synder, 1909) (Teleostei, Gobiidae) from Korea

open access: yesMitochondrial DNA. Part B. Resources
Luciogobius parvulus (Snyder, 1909) is distributed in restricted areas of Japan and South Korea. Here, we report the first complete mitochondrial genome of this species.
Min-Soo Kim   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Formation of Electric Potential Dips and Peaks by Electron-Ion Two-Stream Instability in a Plasma Chamber with an Electron Emitter LaB6 as the Cathode

open access: yesPlasma
This paper presents a conducting-channel model aimed at elucidating the generation of high-energy particles within a plasma chamber. Initially, the chamber is charged with neutral hydrogen gas at a density of approximately ~3.3 × 1022/m3, equivalent to 1
Lou-Chuang Lee   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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