Results 121 to 130 of about 4,635,456 (297)

The Role of Electroencephalogram-Assessed Bandwidth Power in Response to Hypnotic Analgesia

Brain Sciences
Research supports the efficacy of therapeutic hypnosis for reducing acute and chronic pain. However, little is known about the mechanisms underlying these effects.
Mark P. Jensen, Tyler D. Barrett
doaj   +1 more source

SARS-CoV-2 Variants Detection Using TaqMan SARS-CoV-2 Mutation Panel Molecular Genotyping Assays

Infection and Drug Resistance, 2021
Puja Neopane, Jerome Nypaver, Rojeet Shrestha, Safedin Sajo Beqaj Patients Choice Laboratories, Indianapolis, IN, USACorrespondence: Safedin Sajo BeqajPatients Choice Laboratories, 7026 Corporate Dr, Indianapolis, IN, USATel +1 833-569-0440Fax +1 317-802-
Neopane P, Nypaver J, Shrestha R, Beqaj SS   +3 more
doaj  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Isoorotamide-based peptide nucleic acid nucleobases with extended linkers aimed at distal base recognition of adenosine in double helical RNA

Beilstein Journal of Organic Chemistry
Non-coding ribonucleic acid (RNA) impacts many biological processes; however, the complexities of its many roles are not completely understood. Therefore, designing tools for molecular recognition is of paramount importance.
Grant D. Walby, Brandon R. Tessier, Tristan L. Mabee, Jennah M. Hoke, Hallie M. Bleam, Angelina Giglio-Tos, Emily E. Harding, Vladislavs Baskevics, Martins Katkevics, Eriks Rozners, James A. MacKay   +10 more
doaj   +1 more source

Aesthetics, illusion of success and age interactions: disentangling effects in the closed-loop design with sham neurofeedback training

Frontiers in Human Neuroscience
This study examined the influence of the aesthetics of visual feedback stimuli in neurofeedback training (NFB). Previous research shows a lack of specific design standards in NFB research and its application.
Adrian Naas, Adrian Naas, Scott Rohrbach, Payam Sadeghi Shabestari, Patrick Neff, Patrick Neff, Andreas Sonderegger, Andreas Sonderegger   +7 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The Mortality, Clinical Course and Vaccine Status of COVID-19 Patients with Different SARS-Cov-2 Variants

Ahi Evran Medical Journal
Purpose: Several SARS-CoV-2 variants have emerged during the COVID-19 pandemic and alpha, beta, and delta variants were declared as variants of concern. Our aim is to determine the clinical course and vaccine status of COVID-19 patients with alpha, beta,
Tuğçe Ünalan-altıntop, Fikriye Milletli Sezgin, Pelin Onarer, Mustafa Cihangiroğlu, Nilüfer Tali   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source