Results 111 to 120 of about 42,298 (257)

Rebalancing the Neurovascular Axis: NTRK2 Isoform Equilibrium as a Determinant of Pulmonary Endothelial Regeneration

Cell Proliferation, EarlyView.
Summary of the functions of the NTRK2 receptor during lung injury and regeneration. Our recent work using both human organoid and mouse disease models highlights the non‐conventional role of NTRK2 isoforms in regulating pulmonary vasculature and alveolar regeneration during bronchopulmonary dysplasia.
Gan Zhou, Cheng Tan, Yifei Miao
wiley   +1 more source

Evaluation of the zucker diabetic fatty (ZDF) rat as a model for human disease based on urinary peptidomic profiles [PDF]

, 2012
Representative animal models for diabetes-associated vascular complications are extremely relevant in assessing potential therapeutic drugs. While several rodent models for type 2 diabetes (T2D) are available, their relevance in recapitulating renal and ...
Antonia Vlahou, Ariela Benigni, B Jonsson, Bernd Mayer, C Delles, C Weyer, C Zoja, Carlamaria Zoja, CD Wenger, CL Oltman, CS Fox, D Theodorescu, Ferdinand H. Bahlmann, H Mischak, H Mischak, Harald Mischak, J Drube, J Toblli, JO Deguchi, Joachim Jankowski, Julie Klein, Justyna Siwy, K Voros, Karin Jandeleit-Dahm, M Hashemi, M Haubitz, N Ahmed, N Verzijl, ND Rawlings, P Zurbig, Paul Perco, PJ Talmud, PR Cutillas, R Rouse, Robert Stevens, S Andersen, S Wild, SA Varghese, Sophia Kossida, T Nakagawa, TW Kurtz, Wiliam Mullen, Y Benjamini, Y Igarashi   +43 more
core   +3 more sources

Molar‐Incisor Hypomineralisation in Children: The Essential Role of Paediatricians

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Molar‐incisor hypomineralisation is a developmental enamel defect characterised by lower mineral content in the tooth's outer layer, discoloured and structurally fragile teeth that are more prone to sensitivity, breakdown and caries. This review aims to summarise current knowledge on molar‐incisor hypomineralisation and highlight key ...
Sofia Stancati, Viviana Macho, Rita Rodrigues, Cristina Cardoso Silva   +3 more
wiley   +1 more source

Serum Alpha-1 Antitrypsin Levels and the Clinical Course of Chronic Obstructive Pulmonary Disease

International Journal of COPD, 2019
Nozomu Takei,1,* Masaru Suzuki,1,* Hironi Makita,2 Satoshi Konno,1 Kaoruko Shimizu,1 Hiroki Kimura,1 Hirokazu Kimura,1 Masaharu Nishimura1,2 1Department of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University ...
Takei N, Suzuki M, Makita H, Konno S, Shimizu K, Kimura H, Kimura H, Nishimura M   +7 more
doaj  

Integrated dataset on acute phase protein response in chicken challenged with Escherichia coli lipopolysaccharide endotoxin [PDF]

, 2018
Data herein describe the quantitative changes in the plasma proteome in chickens challenged with lipopolysaccharide (LPS), a bacterial endotoxin known to stimulate the host innate immune system obtained by shotgun quantitative proteomic tandem mass tags ...
Bain, Maureen, Eckersall, Peter David, Guillemin, Nicolas, Horvatić, Anita, Kaab, Haider, Kuleš, Josipa, McKeegan, Dorothy, O'Reilly, Emily   +7 more
core   +3 more sources

Salivary Proteomic Signatures in Pregnant Women With Excessive Gingival Bleeding

Oral Diseases, EarlyView.
ABSTRACT Objective This observational, cross‐sectional, and analytical study aimed to explore the pathophysiological mechanisms of gingivitis in pregnancy by analyzing the salivary proteomic profile according to gingival bleeding status. Materials and Methods Pregnant women at the 27th week of gestation or beyond were categorized into two groups: those
Gerson Aparecido Foratori‐Junior, Clovis Bergamin Griso, Amanda Borges Pirondi, Laura Teodoro de Marchi, Talita Mendes Oliveira Ventura, Larissa Tercilia Grizzo, Roosevelt da Silva Bastos, Alejandra Chaparro, Nagihan Bostanci, Marília Afonso Rabelo Buzalaf   +9 more
wiley   +1 more source

Successful Outcome and Biliary Drainage in an Infant with Concurrent Alpha-1-Antitrypsin Deficiency and Biliary Atresia

Case Reports in Surgery, 2017
We describe the rare instance of concomitant biliary atresia and alpha-1-antitrypsin deficiency and the first documented successful portoenterostomy in this scenario.
Andrew W. Wang, Kimberly Newton, Karen Kling   +2 more
doaj   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Feasibility of commercial space manufacturing, production of pharmaceuticals. Volume 1: Executive summary [PDF]

The feasibility of the commercial manufacturing of pharmaceuticals in space is examined. The method of obtaining pharmaceutical company involvement, laboratory results of the separation of serum proteins by the continuous flow electrophoresis process ...

core   +1 more source

Russell-like bodies in plant seeds share common features with prolamin bodies and occur upon recombinant protein production [PDF]

, 2019
Although many recombinant proteins have been produced in seeds at high yields without adverse effects on the plant, endoplasmic reticulum (ER) stress and aberrant localization of endogenous or recombinant proteins have also been reported.
Arcalis, Elsa, Avesani, Linda, Bortesi, Luisa, De Meyer, Thomas, de meyer, thomas, Depicker, Anna, Hilscher, Julia, Ibl, Verena, Morandini, Francesca, Pezzotti, Mario, Pum, Dietmar, Rademacher, Thomas, Stoger, Eva, Vitale, Alessandro   +13 more
core   +2 more sources