Results 71 to 80 of about 2,969,581 (290)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relationships between functional alpha and beta diversities of flea parasites and their small mammalian hosts

Parasitology
We studied the relationships between functional alpha and beta diversities of fleas and their small mammalian hosts in 4 biogeographic realms (the Afrotropics, the Nearctic, the Neotropics and the Palearctic), considering 3 components of alpha diversity (
Boris R. Krasnov, Irina S. Khokhlova, M. Fernanda López Berrizbeitia, Sonja Matthee, Juliana P. Sanchez, Georgy I. Shenbrot, Luther van der Mescht   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Scales matter: regional environment factors affect α diversity but local factors affect β diversity of macroinvertebrates in Thousand Islands Lake catchment area

Ecological Indicators
A more profound comprehension of various facets of biodiversity is essential for advancing sustainable governance of biodiversity and its associated ecosystem services.
Zongwei Lin, Guohao Liu, Kun Guo, Kan Wang, Lishani Wijewardene, Naicheng Wu   +5 more
doaj   +1 more source

Composition, Abundance, and Diversity of the Soil Microbiome Associated with the Halophytic Plants Tamarix aphylla and Halopeplis perfoliata on Jeddah Seacoast, Saudi Arabia

Plants, 2023
The coast of the Red Sea in Jeddah City is home to a unique microbial community that has adapted to extreme environmental conditions. Therefore, it is essential to characterize the microbial community in this unique microbiome to predict how ...
Naseebh N. Baeshen, Lina Baz, Ashwag Y. Shami, Ruba A. Ashy, Rewaa S. Jalal, Aala A. Abulfaraj, Mohammed Refai, Mazen A. Majeed, Samah S. Abuzahrah, Hayam Abdelkader, Nabih A. Baeshen, Mohammed N. Baeshen   +11 more
doaj   +1 more source

Figure 2 - Alpha diversity

, 2022
Alpha diversity distribution before HSCT, at take and post-HSCT.
Marco Fabbrini (14269661)
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The Relationship between Atherosclerosis and Gut Microbiome in Patients with Obstructive Sleep Apnoea

Applied Sciences, 2022
Background: Obstructive sleep apnoea (OSA) and gut dysbiosis are known risk factors for atherosclerosis. However, only very few studies have been focused on the relationship between OSA, atherosclerosis, and the intestinal microbiome, all in animal ...
Helga Szabo, Marton Piroska, Anita Hernyes, Luca Zoldi, Janos Juhasz, Balazs Ligeti, Nora Makra, Dora Szabo, Andras Bikov, Laszlo Kunos, Adam Domonkos Tarnoki, David Laszlo Tarnoki   +11 more
doaj   +1 more source

alpha

, 2014
R code: statistical analysis (ANOVA) on collated alpha diversity metrics (phylogenetic diversity, richness, simpson's evenness, and simpson's diversity) calculated for 100 rarefaction ...
Emily C. Farrer (2926542), Robert L. Sinsabaugh (2905805), Suding, Katharine N., Dean, Sarah L., Porras-Alfaro, Andrea, Farrer, Emily C., Sarah L. Dean (3275622), Sinsabaugh, Robert L., Katharine N. Suding (331341), Andrea Porras-Alfaro (3275619)   +9 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source