Results 61 to 70 of about 3,523,271 (306)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Analyzing Optimal Portfolios of Eleven Assets under Different Constraints [PDF]

open access: yesSHS Web of Conferences
Portfolios, which allocate investor capital to different investments, are a common risk management strategy. It aims to spread investment risk using diversification.
Li Xinyuan
doaj   +1 more source

Job Satisfaction and Performance of Micro Finance Institutions

open access: yesMadhyabindu Journal
Job satisfaction plays a crucial role in determining employee performance, which directly influences the effectiveness and sustainability of Microfinance Institutions (MFIs).
Ashmita Dahal Chhetri
semanticscholar   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Trading algorithms with learning in latent alpha models [PDF]

open access: yesMathematical Finance, 2018
Alpha signals for statistical arbitrage strategies are often driven by latent factors. This paper analyzes how to optimally trade with latent factors that cause prices to jump and diffuse.
P. Casgrain, S. Jaimungal
semanticscholar   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

A Model for Identifying and Analyzing of Strategy Implementation Barriers [PDF]

open access: yesمطالعات مدیریت راهبردی, 2016
This research designs a model for Identifying and Analyzing of Strategy Implementation Barriers in Saman Bank. At first, the theoretical principals and concepts are reviewed and then measuring indicators of each index and dimension are derived by the ...
Mohammad Ali Babayi Zekilaki   +3 more
doaj  

IFRS adoption, corporate governance and faithful representation of financial reporting quality in Nigeria’s development banks

open access: yesCogent Business & Management, 2022
Development banks were designed to achieve the government’s economic priorities that were not adequately addressed by the banking industry. Studies, however, show that the activities of some development banks in Nigeria have not been as impacting as ...
Ayodeji T. Ajibade   +5 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

The Impact of Electronic Banking Service Quality on Customer Satisfaction in Participation Banks: A Case Study of Lebanon

open access: yesTrends in Business and Economics
This research examines the impact of electronic banking services (ease of use, time savings, privacy, and security) on customer satisfaction in Islamic banks in Lebanon, specifically Al Baraka Bank and Arab Finance House.
Ebrucan İslamoğlu, Ahmad Hassan
doaj   +1 more source

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