Results 41 to 50 of about 1,976,936 (266)

Constrained Portfolio Optimization: Markowitz Model and Index Model [PDF]

SHS Web of Conferences
Portfolio optimization is a crucial aspect of contemporary finance, facilitating the efficient balancing of risk and return for investors. In light of the intricate nature of actual investments, constrained portfolio optimization has assumed greater ...
Wang Heran
doaj   +1 more source

The Effect of Social Media on Corporate Innovation: Evidence from Seeking Alpha Coverage

Management Sciences
Seeking Alpha (SA) is the most popular crowdsourced social media platform specializing in the financial analysis of U.S. firms, and it attracts over 17 million visitors per month.
Qiyang He, Henry Leung, Buhui Qiu, Zhou Zhou   +3 more
semanticscholar   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The role of distribution and volatility specification in value at risk estimation: Evidence from the Johannesburg Stock Exchange

Journal of Economic and Financial Sciences, 2012
Given the volatile nature of global financial markets, managing as well as predicting financial risk plays an increasingly important role in banking and finance. The Value at Risk (VaR) measure has emerged as the most prominent measure of downside market
John M. Mwamba, Kruger Pretorius
doaj   +1 more source

Kumaraswamy Alpha Power Lomax Distribution: Properties and Applications in Actuarial Sciences

Statistics, Optimization & Information Computing
The Kumaraswamy alpha power Lomax model, a five-parameter sub-model of the Kumaraswamy alpha power transformed family, is explored in detail. It is of particular interest because there are a variety of possible symmetrical and asymmetrical forms for the ...
Wondimu Fikre, H. S. Kapoor, Kanchan Jain   +2 more
semanticscholar   +1 more source

MARKET MAKING WITH ALPHA SIGNALS

International Journal of Theoretical and Applied Finance, 2020
We show how a market maker employs information about the momentum in the price of the asset (i.e. alpha signal) to make decisions in their liquidity provision strategy in an order-driven electronic market.
Á. Cartea, Yixuan Wang
semanticscholar   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Speaking of Securitization of Financial Assets [PDF]

Ovidius University Annals: Economic Sciences Series, 2017
The history of securitization dates back to “Middle Ages”, as it has emerged into today’s refinements under various ways of obtaining liquidity to finance business growth. As today many blame securitization and low interest rates for the American crisis,
Munteanu Bogdan
doaj  

The role of financial intelligence quotient and financial literacy for paving a path towards financial well-being

Journal of Business Economics and Management, 2023
This study aims to develop an original financial intelligence quotient (FIQ) measurement conceptual model, including guidelines for adequately handling personal finances in four developed areas to serve as benchmarks of financial intelligence.
Algita Miečinskienė, Jelena Stankevičienė, Daiva Jurevičienė, Kamilė Taujanskaitė, Irena Danilevičienė, Laura Gudelytė-Žilinskienė   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source