Results 1 to 10 of about 331,046 (340)

Interferon Alpha Association with Neuromyelitis Optica [PDF]

open access: yesClinical and Developmental Immunology, 2013
Interferon-alpha (IFN-α) has immunoregulatory functions in autoimmune inflammatory diseases. The goal of this study was to determine occurrence and clinical consequences of IFN-α in neuromyelitis optica (NMO) patients.
Nasrin Asgari   +5 more
doaj   +5 more sources

Schwannoma response to interferon alpha

open access: yesInterdisciplinary Neurosurgery, 2017
While cranial nerve schwannomas are typically benign, slow growing tumors, they are associated with morbidity both from the neuropathies and neuralgias they can produce, as well as from the treatments used to address these tumors, typically surgery or ...
Jennifer Novak   +2 more
doaj   +3 more sources

Flaxseed Prevents Interferon-alpha Induced Depressive Behavior in Mice: the α-Linolenic Acid is Essential [PDF]

open access: yesResearch Journal of Pharmacognosy, 2021
Background and objectives: Interferon-alpha (IFN-α) is a cytokine with various clinical applications, but it may induce depression by decreasing tryptophan level and producing neuroactive metabolites.
Azadeh Mesripour*, Maryam Almasi
doaj   +1 more source

CD8+ Lymphocytes from Healthy Blood Donors Secrete Antiviral Levels of Interferon-Alpha

open access: yesViruses, 2023
The adaptive immune response to viral infections features the antigen-driven expansion of CD8+ T cells. These cells are widely recognized for their cytolytic activity that is mediated through the secretion of cytokines such as perforin and granzymes ...
Fernando Teque   +3 more
doaj   +1 more source

Production and Characterization of Polyclonal Antibodies Against Interferon Alpha in Mice

open access: yesBioscientific Review, 2021
The polyclonal antibodies are used extensively for research purposes in many areas of biology, such as immunoprecipitation, histochemistry, enzyme linked immunosorbent assays (ELISA), diagnosis of disease and western blots. Typically, an animal’s immune
Mehreen Fatima   +2 more
doaj   +1 more source

Interferon alpha-induced reduction in the values of myeloid-derived suppressor cells in melanoma patients [PDF]

open access: yesVojnosanitetski Pregled, 2015
Background/Aim. Interaction between tumor cells and host’s immunoregulatory cells in creation of microenvironment that supports tumor progression is the focus of numerous investigations in recent years.
Stanojević Ivan   +11 more
doaj   +1 more source

Interferons in Traumatic Brain and Spinal Cord Injury: Current Evidence for Translational Application

open access: yesFrontiers in Neurology, 2018
This review article provides a general perspective of the experimental and clinical work surrounding the role of type-I, type-II, and type-III interferons (IFNs) in the pathophysiology of brain and spinal cord injury. Since IFNs are themselves well-known
Francesco Roselli   +4 more
doaj   +1 more source

Pegylated interferon-alpha-2a for the treatment of ocular surface squamous neoplasia

open access: yesOman Journal of Ophthalmology, 2022
Ocular surface squamous neoplasia (OSSN) is the most common nonpigmented ocular surface neoplasm. Interferon-alpha (IFNα)-2b has been proved to be an effective immunotherapeutic agent to treat OSSN.
Murtuza Nuruddin   +2 more
doaj   +1 more source

Proliferative retinopathy in a diabetic on interferon therapy: A diagnostic dilemma

open access: yesKerala Journal of Ophthalmology, 2016
Hepatitis C virus (HCV) is a blood-borne RNA virus that causes hepatitis C, chronic liver disease, and hepatocellular carcinoma. Patients with HCV infection are now treated with a combination of interferon alpha, which has antiviral and immunomodulatory ...
Prajina Rahul   +4 more
doaj   +1 more source

Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletion

open access: yesJournal of Translational Medicine, 2008
Background To determine the role of interferon-alpha in controlling HIV infection we phenotypically and functionally analyzed circulating plasmacytoid dendritic cells (pDC), which are known to be the highest interferon-alpha producing cells, in 33 ...
Plebani Alessandro   +10 more
doaj   +1 more source

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