Results 101 to 110 of about 169,723 (293)

Interferon-alpha treatment for chronic hepatitis C in children

The Turkish Journal of Pediatrics, 2000
Interferon-alpha therapy has been proven efficient in chronic hepatitis C infection. Although it has been used as a standard therapy in adults, there are limited data on benefits of interferon treatment in children.
A Yüce, N Koçak, F Gürakan, H Ozen
doaj  

Comparative Study of Protection against Newcastle Disease in Young Broilers Administered Natural Chicken Alpha Interferon via Oral and Intramuscular Routes. [PDF]

mSphere, 2020
Anjum FR, Rahman SU, Aslam MA, Qureshi AS.   +3 more
europepmc   +1 more source

Sensitive inhibitory effect of interferon-alpha on M-protein secretion of human myeloma cells [PDF]

, 1989
H Tanaka, O Tanabe, K Iwato, Hideki Asaoku, Hideaki Ishikawa, M Nobuyoshi, Masanori Kawano, Atsushi Kuramoto   +7 more
openalex   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Multivariate Screening and Automated Clustering of Macrophage Immunoreactome to Nanoparticles and Photothermal Therapy

Advanced Science, EarlyView.
Predicting immune responses to treatments, including nanomedicines, with high throughput test is challenging due to the immunoreactome's complexity and plasticity. A predictive screening platform integrating pathway activation and gene profiling in macrophages has been developed as a versatile tool for designing effective immunotherapies.
Sonia Becharef, Léa Jabbour, Nassima Bekaddour, Giulio Avveduto, Nathalie Luciani, Gautier Laurent, Rana Bazzi, Edouard Alphandery, Stéphane Roux, Amanda K. A. Silva, Kelly Aubertin, Jean‐Philippe Herbeuval, Florence Gazeau   +12 more
wiley   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

PHARMACOKINETIC STUDY OF A HUMAN RECOMBINANT INTERFERON (Re-IFN-^|^alpha;A) IN CYNOMOLGUS MONKEYS BY 2'-5' OLIGOADENYLATE SYNTHETASE ASSAY

, 1985
Hisaichi BANNAI, Masashi Tatsumi, Masayoshi Kohase, Eiko Onishi, Shudo Yamazaki   +4 more
openalex   +2 more sources

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

Advanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui, Zining Wang, Zixuan Guo, Hongxia Zhang, Yongxiang Liu, Huanling Zhang, Huan Jin, Feifei Xu, Xiaojuan Wang, Chunyuan Xie, Hui Guo, Tiantian Wang, Yanxun Lin, Qi Zhao, Penghui Zhou, Jing Tan, Jin‐Xin Bei, Peng Huang, Jinyun Liu, Xiaojun Xia   +19 more
wiley   +1 more source

B. C. G. plus recombinant interferon α2b in superficial bladder cancer

Indian Journal of Urology, 2001
We have studied the efficacy of adjuvant therapy in the form of low dose B.C.G. and interferon alpha 2b. In the present study 7patients with superficial bladder car-cinoma (6 recurrent and I primary) have been treated by TURBT and intravesical ...
Gyan Prakash Singh, Usha Singh, U S Diwedi, P B Singh   +3 more
doaj