Results 11 to 20 of about 362,526 (330)

Alpha/beta and gamma interferons are induced by infection with noncytopathic bovine viral diarrhea virus in vivo [PDF]

, 2002
In contrast to the results of previous in vitro studies, experimental infection of calves with noncytopathic bovine viral diarrhea virus (ncpBVDV) was found to induce strong alpha/beta and gamma interferon responses in gnotobiotic animals.
Brackenbury, L.S, Carr, B V, Charleston, B, Fray, M D, Hope, Jayne, Howard, CJ, Morrison, Ivan   +6 more
core   +2 more sources

Pegylated interferon-alpha-2a for the treatment of ocular surface squamous neoplasia

Oman Journal of Ophthalmology, 2022
Ocular surface squamous neoplasia (OSSN) is the most common nonpigmented ocular surface neoplasm. Interferon-alpha (IFNα)-2b has been proved to be an effective immunotherapeutic agent to treat OSSN.
Murtuza Nuruddin, Soma Rani Roy, Fahmida Hoque   +2 more
doaj   +1 more source

Twenty-four vs. forty-eight weeks of re-therapy with interferon alpha 2b and ribavirin in interferon alpha monotherapy relapsers with chronic hepatitis C. [PDF]

, 2003
Roughly 50% of patients with chronic hepatitis C, who relapsed after a previous monotherapy with interferon alpha, will respond in a sustained fashion to 24 weeks of re-therapy with the combination of interferon alpha plus ribavirin.
August-Jörg, B.S., Borovicka, J., Dufour, J.F., Gonvers, J.J., Henz, S., Hermann, R., Meyenberger, C., Renner, E.L., Weitz, M.   +8 more
core   +1 more source

Regulation of Murine Class I Genes by Interferons is Controlled by Regions Located Both 5' and 3' to the Transcription Initiation Site [PDF]

, 1987
Interferons regulate the expression of a large number of mammalian genes, including the major histocompatibility antigen genes. To investigate the mechanisms involved in interferon action, we have analyzed the ability of murine H-2Ld and H-2Dd DNA ...
Hood, Leroy, Korber, Bette, Stroynowski, Iwona   +2 more
core   +1 more source

Retreatment with interferon-alpha and ribavirin in primary interferon-alpha non-responders with chronic hepatitis C [PDF]

, 2000
Background/Aims: Combination therapy with interferon-alpha (IFN-alpha) plus ribavirin is more efficacious than IFN-alpha monotherapy in previously untreated patients with chronic hepatitis C and patients with IFN-alpha relapse.
Berg, Thomas, Hoffmann, Robert M., Hopf, Uwe, Lafrenz, Michael, Leifeld, Ludger, Pape, Gerd R., Spengler, Ulrich, Teuber, Gerlinde, Zeuzem, Stefan   +8 more
core   +1 more source

Type I interferon-dependent gene MxA in perinatal HIV-infected patients under antiretroviral therapy as marker for therapy failure and blood plasmacytoid dendritic cells depletion

Journal of Translational Medicine, 2008
Background To determine the role of interferon-alpha in controlling HIV infection we phenotypically and functionally analyzed circulating plasmacytoid dendritic cells (pDC), which are known to be the highest interferon-alpha producing cells, in 33 ...
Plebani Alessandro, Lonardi Silvia, Spinelli Elena, Chiarini Marco, Sottini Alessandra, Serana Federico, Facchetti Fabio, Ghidini Claudia, Badolato Raffaele, Caimi Luigi, Imberti Luisa   +10 more
doaj   +1 more source

Baseline anti-NS4a antibodies in combination with on-treatment quantitative HCV-RNA reliably identifies nonresponders to pegylated interferon-ribavirin combination therapy after 4 weeks of treatment [PDF]

, 2010
Background Early detection of nonresponders to hepatitis C therapy limits unnecessary exposure to treatment and its side-effects. A recent algorithm combining baseline anti-NS4a antibodies and on-treatment quantitative PCR identified nonresponders to a ...
de Knegt, Robert J, Desombere, Isabelle, Haagmans, Bart, Hansen, Bettina, Janssen, Harry LA, Leroux-Roels, Geert, Orlent, Hans, Schalm, Solko W, Van Vlierberghe, Hans   +8 more
core   +1 more source

Proliferative retinopathy in a diabetic on interferon therapy: A diagnostic dilemma

Kerala Journal of Ophthalmology, 2016
Hepatitis C virus (HCV) is a blood-borne RNA virus that causes hepatitis C, chronic liver disease, and hepatocellular carcinoma. Patients with HCV infection are now treated with a combination of interferon alpha, which has antiviral and immunomodulatory ...
Prajina Rahul, Manoj Venugopal, S Sija, R S Dhanya, Elizabeth John   +4 more
doaj   +1 more source

Response to combination therapy with interferon alfa-2a and ribavirin in chronic hepatitis C according to a TNF-alpha promoter polymorphism [PDF]

, 2003
Background. Tumor necrosis factor-alpha (TNF-alpha) is involved in the pathogenesis of chronic active hepatitis C. Polymorphisms in the promoter region of the TNF-alpha gene can alter the TNF-alpha expression and modify the host immune response.
Folwaczny, Christian, Glas, J., Konig, A., Martin, K., Schaefer, M., Schiemann, Uwe, Schmidt, F., Simperl, C., Torok, P.   +8 more
core   +1 more source

Interferon Alpha Association with Neuromyelitis Optica

Clinical and Developmental Immunology, 2013
Interferon-alpha (IFN-α) has immunoregulatory functions in autoimmune inflammatory diseases. The goal of this study was to determine occurrence and clinical consequences of IFN-α in neuromyelitis optica (NMO) patients.
Nasrin Asgari, Anne Voss, Troels Steenstrup, Kirsten Ohm Kyvik, Egon Stenager, Soeren Thue Lillevang   +5 more
doaj   +1 more source