Results 61 to 70 of about 467,308 (290)

Energetic particle-driven compressional Alfvén eigenmodes and prospects for ion cyclotron emission studies in fusion plasmas

New Journal of Physics, 2016
As a fundamental plasma oscillation the compressional Alfvén waves (CAWs) are interesting for plasma scientists both academically and in applications for fusion plasmas. They are believed to be responsible for the ion cyclotron emission (ICE) observed in
N N Gorelenkov
doaj   +1 more source

Experimental observation of neutron-neutron correlations in nucleus 6He from 3H(α,pα)nn reaction

Ядерна фізика та енергетика, 2019
The projections of two-dimensional spectra of p-α coincidences from the four-particle reaction of 3H(α, pα)nn with the energy of alpha-particles 27.2 MeV on the energy axis of alpha-particles for six pairs of angles are analyzed. The results of the Monte
O. M. Povoroznyk, O. K. Gorpinich
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Repulsive Four-Body Interactions of $\alpha$ Particles and Quasi-Stable Nuclear $\alpha$-Particle Condensates in Heavy Self-Conjugate Nuclei

, 2018
We study the effects of repulsive four-body interactions of $\alpha$ particles on nuclear $\alpha$-particle condensates in heavy self-conjugate nuclei using a semi-analytic approach, and find that the repulsive four-body interactions could decrease the ...
Bai, Dong, Ren, Zhongzhou
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Calculation of alpha particle single-event spectra using a neural network

Frontiers in Oncology
IntroductionA neural network was trained to accurately predict the entire single-event specific energy spectra for use in alpha-particle microdosimetry calculations.MethodsThe network consisted of 4 inputs and 21 outputs and was trained on data ...
Layth Alkhani, Jason P. Luce, Pablo Mínguez Gabiña, John C. Roeske   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Light yield measurement of the Ce3+ activated LuAG nano-powder garnet scintillating detector

ENP Engineering Science Journal
This paper focuses on the characterization of nano-powder (NP) scintillator, specifically presenting preliminary results of the measurement of the light yield (LY) of a newly synthesized Lutetium Aluminum (LuAG) garnet phosphor NP scintillator, doped ...
Hamza Mekki, Lakhdar Guerbous, Hicham BOUSBIA-SALAH, Billel Zahra, Allaoua Boukerika   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Efficiency of Low Alpha Dose Therapy for Achieving Complete Skin Tissue Regeneration [PDF]

Iranian Journal of Medical Physics
Introduction: The process of wound healing represents a dynamic and multifaceted phenomenon characterized by intricate cellular and molecular mechanisms aimed at the restoration of tissue integrity.
Madyan Khalaf, Baida Ahmed, Sahar Al-Sharqi   +2 more
doaj   +1 more source