Results 61 to 70 of about 182,926 (262)

Calculation of alpha particle single-event spectra using a neural network

Frontiers in Oncology
IntroductionA neural network was trained to accurately predict the entire single-event specific energy spectra for use in alpha-particle microdosimetry calculations.MethodsThe network consisted of 4 inputs and 21 outputs and was trained on data ...
Layth Alkhani, Jason P. Luce, Pablo Mínguez Gabiña, John C. Roeske   +3 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Light yield measurement of the Ce3+ activated LuAG nano-powder garnet scintillating detector

ENP Engineering Science Journal
This paper focuses on the characterization of nano-powder (NP) scintillator, specifically presenting preliminary results of the measurement of the light yield (LY) of a newly synthesized Lutetium Aluminum (LuAG) garnet phosphor NP scintillator, doped ...
Hamza Mekki, Lakhdar Guerbous, Hicham BOUSBIA-SALAH, Billel Zahra, Allaoua Boukerika   +4 more
doaj   +1 more source

Molecular Dynamics Study on the Mechanism of Gallium Nitride Radiation Damage by Alpha Particles. [PDF]

Materials (Basel), 2023
Liu Y, Xiong Z, Ouyang X.
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Resistive wall mode and fishbone mode in ITER steady state scenario: roles of fusion-born alphas and plasma flow

Nuclear Fusion
Drift-kinetic effects of fusion-born alpha particles on the n = 1 ( n is the toroidal mode number) resistive wall mode (RWM) is numerically investigated for a recent design of the ITER 10 MA steady state plasma scenario, utilizing a magneto-hydrodynamic (
Hongda He, Yueqiang Liu, Guangzhou Hao, Jinxia Zhu, Yong Shen, Guoyao Zheng   +5 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Energy-selective confinement of fusion-born alpha particles during internal relaxations in a tokamak plasma. [PDF]

Nat Commun, 2022
Bierwage A, Shinohara K, Kazakov YO, Kiptily VG, Lauber P, Nocente M, Štancar Ž, Sumida S, Yagi M, Garcia J, Ide S, JET Contributors.   +11 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source