Results 141 to 150 of about 315,375 (279)
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Testosterone, cortisol, and fNIRS-based cortical activation associated with competitive task persistence and difficulty. [PDF]
J NeuroendocrinolCasto KV, Cohen DJ, Hicks C, Bowser A.
europepmc +1 more source
Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction
Advanced Science, EarlyView.During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao +8 more
wiley +1 more source
ALPHABET REFORM IN UZBEKISTAN: HISTORY, CHALLENGES AND PERSPECTIVES
Многоязычие в образовательном пространствеThe article presents the history of writing system reforms in Uzbekistan, starting from the transition to Arabic script in the 8 century and ending with the modern changes in the alphabet.
U.K. Khudaybergenova
doaj
Soft Multiaxial Strain Mapping Interface with AI-Driven Decoding for Silent Speech in Noise. [PDF]
Cyborg Bionic SystHong S, Yoo J, Park SM.
europepmc +1 more source
Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity
Advanced Science, EarlyView.Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu +8 more
wiley +1 more source
Influence of Phosphate Activation Chemistry on the Selection of the Primordial Genetic Alphabet. [PDF]
J Am Chem SocBošković F +3 more
europepmc +1 more source
Advanced Science, EarlyView.This study presents a hierarchically channeled graphitized nanoarchitecture (HPGC‐Z67) as a novel nano‐diagnostic platform. It enables sensitive and efficient N‐glycan extraction from plasma, significantly reducing processing time and cost. The platform identifies pivotal N‐glycans to accurately differentiate between infectious and non‐infectious ...
Yiwen Lin +5 more
wiley +1 more source
Refinements and Generalizations of the Shannon Lower Bound via Extensions of the Kraft Inequality. [PDF]
Entropy (Basel)Merhav N.
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Background & Aims: Cancer‐associated fibroblasts (CAFs) drive immunosuppression in hepatocellular carcinoma (HCC). However, their metabolic regulation remains poorly defined. We investigated the role of nicotinamide N‐methyltransferase (NNMT) in CAFs. Approach & Results: High NNMT expression in CAF tissues was confirmed by western blotting and
Shounan Lu +20 more
wiley +1 more source