Results 1 to 10 of about 10,817 (123)

Human Alphacoronavirus Universal Primers for Genome Amplification and Sequencing

Frontiers in Microbiology, 2022
Rapid and accurate sequencing covering the entire genome is essential to identify genetic variations of viral pathogens. However, due to the low viral titers in clinical samples, certain amplification steps are required for viral genome sequencing.
Sungmi Choi, Kwan Woo Kim, Keun Bon Ku, Seong-Jun Kim, Changwoo Park, Changwoo Park, Changwoo Park, Dongju Park, Dongju Park, Dongju Park, Seil Kim, Seil Kim, Seil Kim, Hana Yi, Hana Yi   +14 more
doaj   +3 more sources

Genomic Characterization of a Novel Alphacoronavirus Isolated from Bats, Korea, 2020

Viruses, 2021
Coronavirus, an important zoonotic disease, raises concerns of future pandemics. The bat is considered a source of noticeable viruses resulting in human and livestock infections, especially the coronavirus. Therefore, surveillance and genetic analysis of
Hai-Quynh Do, Van-Giap Nguyen, Chul-Un Chung, Yong-Shin Jeon, Sook Shin, Kuem-Chan Jang, Le Bich Hang Pham, Aeri Kong, Cheong-Ung Kim, Yong-Ho Park, Bong-Kyun Park, Hee-Chun Chung   +11 more
doaj   +3 more sources

Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats

Viruses, 2019
Bats have been identified as a natural reservoir of a variety of coronaviruses (CoVs). Several of them have caused diseases in humans and domestic animals by interspecies transmission.
Ning Wang, Chuming Luo, Haizhou Liu, Xinglou Yang, Ben Hu, Wei Zhang, Bei Li, Yan Zhu, Guangjian Zhu, Xurui Shen, Cheng Peng, Zhengli Shi   +11 more
doaj   +3 more sources

Virome and Microbiome of Florida Bats Illuminate Viral Co-Infections, Dietary Viral Signals, and Gut Microbiome Shifts [PDF]

Microorganisms
Florida’s bat virome remains poorly characterized despite the state’s high bat species diversity and conservation importance. We characterized viral metagenomes from rectal tissues, anal swabs, and feces of Myotis austroriparius and Tadarida brasiliensis
Julia E. Paoli, Thanaporn Thongthum, Maclean Bassett, Jakob Beardsley, Massimiliano S. Tagliamonte, Melanie N. Cash, Jason Spertus Newman, Lisa M. Smith, Benjamin D. Anderson, Marco Salemi, Kuttichantran Subramaniam, Michael E. von Fricken, Elizabeth Braun de Torrez, Verity Mathis, Carla N. Mavian   +14 more
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Molnupiravir Inhibits Replication of Multiple Alphacoronavirus suis Strains in Feline Cells [PDF]

Pathogens
The cross-species spillover of coronaviruses is considered a serious public health risk. Feline coronavirus (FCoV), canine coronavirus (CCoV), and transmissible gastroenteritis virus (TGEV) are all classified under Alphacoronavirus suis and infect ...
Tomoyoshi Doki, Kazuki Shinohara, Kaito To, Tomomi Takano   +3 more
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Human alphacoronavirus replication and innate immune induction in airway culture systems [PDF]

mBio
Compared with lethal betacoronaviruses, there is limited knowledge of how human alphacoronaviruses HCoV-NL63 (NL63) and HCoV-229E (229E) interact with host innate immune responses.
Alejandra Fausto, Clayton J. Otter, Leonel Torres, Ebba K. Blomqvist, Nicole Bracci, David M. Renner, Li Hui Tan, Devon Mooring, Nadine Ebert, Bettina Trüeb, Volker Thiel, Noam A. Cohen, James M. Burke, Susan R. Weiss   +13 more
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Detection and genetic characterization of alphacoronaviruses in co-roosting bat species, southeastern Kenya. [PDF]

PLoS Neglected Tropical Diseases
Bats are associated with some of the most significant and virulent emerging zoonoses globally, yet research and surveillance of bat pathogens remains limited across parts of the world.
Joseph G Ogola, Hussein Alburkat, Teemu Smura, Lauri Kareinen, Ravi Kant, Essi M Korhonen, Tamika J Lunn, Moses Masika, Paul W Webala, Philip Nyaga, Omu Anzala, Olli Vapalahti, Kristian M Forbes, Tarja A Sironen   +13 more
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Detection of Alphacoronavirus vRNA in the Feces of Brazilian Free-Tailed Bats (Tadarida brasiliensis) from a Colony in Florida, USA

Diseases, 2017
Bats are natural reservoirs of coronaviruses and other viruses with zoonotic potential. Florida has indigenous non-migratory populations of Brazilian free-tailed bats (Tadarida brasiliensis) that mostly roost in colonies in artificial structures.
Tania S. Bonny, John P. Driver, Taylor Paisie, Marco Salemi, John Glenn Morris, Lisa A. Shender, Lisa Smith, Carolyn Enloe, Kevin Oxenrider, Jeffery A. Gore, Julia C. Loeb, Chang-Yu Wu, John A. Lednicky   +12 more
doaj   +3 more sources

Genomic characterization of Alphacoronavirus from Mops condylurus bats in Nigeria

Virus Research, 2023
Coronaviruses (CoVs) are responsible for sporadic, epidemic and pandemic respiratory diseases worldwide. Bats have been identified as the reservoir for CoVs. To increase the number of complete coronavirus genomes in Africa and to comprehend the molecular
Uwem George, Oluwadamilola George, Judith Oguzie, Oluwadamilola Osasona, Babatunde Motayo, Joshua Kamani, Philomena Eromon, Onikepe Folarin, Anise Happi, Isaac Komolafe, Christian Happi   +10 more
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Genome-scale CRISPR screen identifies TMEM198 driving double membrane vesicle formation in swine alphacoronavirus and murine betacoronavirus infected cells. [PDF]

PLoS Pathogens
COVID-19 pandemic caused by the SARS-CoV-2 which is well-publicized cross-species transmissibility. SARS-CoV-2 belongs to genus Betacoronavirus, several pathogenic alphacoronaviruses have shown similar patterns of emergence.
Lei Shi, Yu Zhang, Yueyue Duan, Maowen Sun, Cong Yuan, Liyan Cao, Xiangyu Kong, Wenlong Zhang, Haixue Zheng, Qi Wang   +9 more
doaj   +2 more sources