Results 161 to 170 of about 11,673 (180)

Molecular Diversity of Alphacoronavirus 1 in Dogs and Cats in Colombia [PDF]

Heliyon, 2020
Alphacoronavirus 1 (subgenus Tegacovirus, genus Alphacoronavirus, family Coronaviridae), which encompasses transmissible gastroenteritis virus (TGEV), feline coronavirus (FCoV) and canine coronavirus (CCoV), is an important pathogen that can cause severe gastroenteritis and is distributed worldwide.
Sueli Taniwaki, Paulo Eduardo Brandao, P E Brandão   +2 more
exaly   +4 more sources

Discovery of a Novel Swine Enteric Alphacoronavirus (SeACoV) in Southern China

Veterinary Microbiology, 2017
Outbreaks of diarrhea in newborn piglets without detection of transmissible gastroenteritis virus (TGEV), porcine epidemic diarrhea virus (PEDV) and porcine deltacoronavirus (PDCoV), have been recorded in a pig farm in southern China since February 2017.
Yao-Wei Huang, Pengwei Zhao, Yong-Le Yang   +2 more
exaly   +3 more sources

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First Evidence That an Emerging Mammalian Alphacoronavirus Is Able to Infect an Avian Species

Transboundary and Emerging Diseases, 2022
A novel swine enteric alphacoronavirus, swine acute diarrhoea syndrome coronavirus (SADS-CoV), related to Rhinolophus bat CoV HKU2 in the subgenus Rhinacovirus emerged in southern China in 2017, causing diarrhoea in newborn piglets, and critical questions remain about the pathogenicity, cross-species transmission and potential animal reservoirs.
Zhuangzhuang Zhao, Yao-Wei Huang, Yong-Le Yang   +2 more
exaly   +3 more sources

Analysis of Codon Usage Patterns of Porcine Enteric Alphacoronavirus and Its Host Adaptability

Virology, 2023
Porcine enteric alphacoronavirus (PEAV) is a newly emerging swine enteropathogen that poses a threat to the swine industry. To understand the PEAV genome evolution, we performed a comprehensive analysis of the codon usage patterns in fifty-nine PEAV strains currently available.
Yongning Zhang, Xinna Ge, Hanchun Yang
exaly   +3 more sources

Structural and Biological Basis of Alphacoronavirus nsp1 Associated With Host Proliferation and Immune Evasion [PDF]

Viruses, 2020
Non-structural protein 1 (nsp1) is only characterized in alphacoronaviruses (α-CoVs) and betacoronaviruses (β-CoVs). There have been extensive researches on how the β-CoVs nsp1 regulates viral virulence by inhibiting host protein synthesis, but the regulatory mechanism of the α-CoVs nsp1 is still unclear.
Gui-Qing Peng, Zhenfang Fu, Zhou Shen
exaly   +4 more sources

Procyanidins inhibit alphacoronavirus infection by reducing interferon antagonism

Phytomedicine
The development of coronavirus drugs has primarily focused on targeting viral components, such as RNA-dependent RNA polymerase (RdRP), with relatively little attention given to enhancing host antiviral defenses. α-Coronaviruses, including human-infecting HCoV-NL63 and HCoV-229E, utilize immune evasion strategies such as suppressing host interferon ...
Yi Liu, Xue Wang, Xuefei Wang, Wensai Mao, Yujing Weng, Yiqing Zhao, Cong Duan, Jiufeng Wang   +7 more
openaire   +2 more sources

Generation of whole-porcine neutralizing antibodies of an alphacoronavirus by single B cell antibody technology

Antiviral Research, 2023
Porcine epidemic diarrhea virus (PEDV) is an alphacoronavirus that causes severe morbidity and mortality in piglets, resulting in substantial economic losses to the swine industry. While vaccination is currently the most effective preventive measure, existing vaccines fail to provide complete and reliable protection against PEDV infection. Consequently,
Sheng Wang, Zhichen Wang, Ying Li, Shaoyu Tu, Jiahui Zou, Yanqing Cheng, Huawei Zhang, Sizhu Suolang, Hongbo Zhou   +8 more
openaire   +2 more sources

Porcine Enteric Alphacoronavirus Infection Increases Lipid Droplet Accumulation to Facilitate the Virus Replication

Journal of Integrative Agriculture
Coronaviruses are widely transmissible between humans and animals, causing diseases of varying severity. Porcine enteric alphacoronavirus (PEAV) is a newly-discovered pathogenic porcine enteric coronavirus in recent years, which causes watery diarrhea in
Dongdong Wu, Lang Gong, Guihong Zhang
exaly   +2 more sources

Genomic Characterization of Alphacoronavirus from Mops Condylurus Bats, Nigeriagenomic Characterization of Alphacoronavirus from Mops Condylurus Bats, Nigeria

2023
Uwem George, Oluwadamilola George, Judith Oguzie, Oluwadamilola Osasona, Babatunde Motayo, Joshua Kamani, Philomena Eromon, Onikepe Folarin, Anise Happi, Isaac Komolafe, Christian T. Happi   +10 more
openaire   +1 more source

Porcine Enteric Alphacoronavirus Entry Through Multiple Pathways (Caveolae, Clathrin, and Macropinocytosis) Requires Rab GTPases for Endosomal Transport.

Journal of Virology, 2023
Lang Gong, Guihong Zhang, Xiongnan Chen
exaly