Human Alphacoronavirus Universal Primers for Genome Amplification and Sequencing
Frontiers in Microbiology, 2022 Rapid and accurate sequencing covering the entire genome is essential to identify genetic variations of viral pathogens. However, due to the low viral titers in clinical samples, certain amplification steps are required for viral genome sequencing.
Sungmi Choi +14 more
doaj +3 more sources
New Alphacoronavirus in Mystacina tuberculata Bats, New Zealand [PDF]
Emerging Infectious Diseases, 2014 Because of recent interest in bats as reservoirs of emerging diseases, we investigated the presence of viruses in Mystacina tuberculata bats in New Zealand. A novel alphacoronavirus sequence was detected in guano from roosts of M.
Richard J. Hall +5 more
doaj +3 more sources
Genomic characterization of Alphacoronavirus from Mops condylurus bats in Nigeria
Virus Research, 2023 Coronaviruses (CoVs) are responsible for sporadic, epidemic and pandemic respiratory diseases worldwide. Bats have been identified as the reservoir for CoVs. To increase the number of complete coronavirus genomes in Africa and to comprehend the molecular
Uwem George +10 more
doaj +3 more sources
Receptor-binding loops in alphacoronavirus adaptation and evolution [PDF]
Nature Communications, 2017 Coronaviruses have a relatively high mutation rate, potentially allowing fast adaptation to changing pressures. Here, Wong et al. provide the structure of the receptor-binding domain (RBD) of the human coronavirus HCoV-229E and its receptor and analyze ...
Alan H. M. Wong +8 more
doaj +4 more sources
Presence of Alphacoronavirus in Tree- and Crevice-Dwelling Bats from Portugal
VirusesCoronaviruses (CoVs) are RNA viruses capable of infecting a wide range of hosts, including mammals and birds, and have caused significant epidemics such as the ongoing COVID-19 pandemic.
Mahima Hemnani +5 more
doaj +5 more sources
Seasonality of Common Human Coronaviruses, United States, 2014–2021
Emerging Infectious Diseases, 2022 The 4 common types of human coronaviruses (HCoVs)—2 alpha (HCoV-NL63 and HCoV-229E) and 2 beta (HCoV-HKU1 and HCoV-OC43)—generally cause mild upper respiratory illness.
Melisa M. Shah +5 more
doaj +1 more source
Myotis fimbriatus Virome, a Window to Virus Diversity and Evolution in the Genus Myotis
Viruses, 2022 Significant efforts have been made to characterize viral diversity in bats from China. Many of these studies were prospective and focused mainly on Rhinolophus bats that could be related to zoonotic events. However, other species of bats that are part of
Alix Armero +9 more
doaj +1 more source
Alphacoronavirus Protein 7 Modulates Host Innate Immune Response [PDF]
Journal of Virology, 2013 ABSTRACTInnate immune response is the first line of antiviral defense resulting, in most cases, in pathogen clearance with minimal clinical consequences. Viruses have developed diverse strategies to subvert host defense mechanisms and increase their survival.
Cruz, Jazmina L. G. +5 more
openaire +3 more sources
A Cross Sectional Sampling Reveals Novel Coronaviruses in Bat Populations of Georgia
Viruses, 2021 Mammal-associated coronaviruses have a long evolutionary history across global bat populations, which makes them prone to be the most likely ancestral origins of coronavirus-associated epidemics and pandemics globally.
Lela Urushadze +10 more
doaj +1 more source
Transmissible Gastroenteritis Virus: An Update Review and Perspective
Viruses, 2023 Transmissible gastroenteritis virus (TGEV) is a member of the alphacoronavirus genus, which has caused huge threats and losses to pig husbandry with a 100% mortality in infected piglets.
Yiwu Chen +9 more
doaj +1 more source