Results 231 to 240 of about 47,878 (245)

Innate Recognition of Alphaherpesvirus DNA

2015
Alphaherpesviruses include human and animal pathogens, such as herpes simplex virus type 1, which establish life-long latent infections with episodes of recurrence. The immunocompetence of the infected host is an important determinant for the outcome of infections with alphaherpesviruses. Recognition of pathogen-associated molecular patterns by pattern
Luecke, Stefanie, Paludan, Søren R
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Recombination in the alphaherpesvirus bovine herpesvirus 1

Veterinary Microbiology, 2006
Herpesviruses are DNA viruses characterized by a low rate of nucleotide substitution. Therefore, other mechanisms must be involved to their evolution, like recombination that can be seen as an essential evolutionary driving force of these viruses. Recombination contributes to the long-term evolution of alphaherpesviruses.
Thiry, Etienne, Muylkens, Benoît, Meurens, F., Gogev, S., Thiry, Julien, Vanderplasschen, Alain, Schynts, F.   +6 more
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Alphaherpesvirus DNA replication

2007
DNA replication in alphaherpesviruses has been the subject of study in bursts over the years. Interest in the subject depends not just on simple curiosity about this central feature of the viral growth cycle, but also because DNA replication is a potentially useful target for antiviral therapy, as has already been shown with agents such as acyclovir ...
John Hay, William T. Ruyechan
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Infectious Delivery of Alphaherpesvirus Bacterial Artificial Chromosomes

2014
Bacterial artificial chromosomes (BACs) can accommodate and stably propagate the genomes of large DNA viruses in E. coli. As DNA virus genomes are often per se infectious upon transfection into mammalian cells, their cloning in BACs and easy modification by homologous recombination in bacteria has become an important strategy to investigate the ...
Tobler, Kurt, Fraefel, Cornel
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Antiviral Drugs Against Alphaherpesvirus

2018
The discovery of acyclovir and penciclovir has led to the development of a successful systemic therapy for treating herpes simplex virus infection and varicella-zoster virus infection, and the orally available prodrugs, valacyclovir and famciclovir, have improved antiviral treatment compliance.
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Photodisinfection of Alphaherpesvirus 1 in Bovine Semen

Journal of Photochemistry and Photobiology B: Biology
Reproductive biotechnologies are widely consolidated as a methodology in cattle breeding and have an important impact on the genetic improvement of cattle herds. Semen is an important source of dissemination of pathogenic microorganisms during reproductive procedures. To ensure the sanitary quality of the semen, it is essential to consider the presence
Taise Maria, Dos Anjos Oliveira, Amanda Vargas, Teles, Maria Lúcia, Gambarini, Keyla, de Oliveira Ribeiro, Eli Silveira Alves, Ducas, Klayto José Gonçalves, Dos Santos, Carlos Jorge Pereira, Monteiro, Elisangela, de Paula Silveira Lacerda, Leonardo Pereira, Franchi, Pablo José, Gonçalves, Guilherme Rocha Lino, de Souza   +10 more
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Emerging functions of alphaherpesvirus genes

Seminars in Virology, 1993
Abstract We know from complete sequencing of three alphaherpesvirus genomes that these large DNA viruses around 70 genes. In many cases little is known of gene function. Features of predicted amino acid sequences have given a number of clues to functions, mostly for enzymes and membrane-associated proteins. Genetic analyzes have very strikingly shown
D.J. McGeoch, B.C. Barnett, C.A. MacLean
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The neurobiology of alphaherpesvirus infections.

Acta veterinaria Hungarica, 1995
In this review we have tried to outline some of the recent experimental data which has contributed to our understanding the neurobiology of herpesviruses. We have attempted to draw together the threads of several different but related disciplines, i.e.
N L, Meyers, A A, Nash
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Genetic comparison of human alphaherpesvirus genomes

2007
Human herpesviruses 1, 2 , and 3 (herpes simplex virus 1 (HSV-1), herpes simplex virus 2 (HSV-2), and varicella-zoster virus (VZV)) have been classified as alphaherpesviruses based originally upon their biological properties, and subsequently on the sequences of their respective genomes (Minson et al ., 2000; Pellett and Roizman, in press).
Joel D. Baines, Philip E. Pellett
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[Regulation of alphaherpesvirus gene expression].

Nihon rinsho. Japanese journal of clinical medicine, 2000
Human alphaherpesviruses are common human pathogens associated with a variety of diseases. The striking characteristics of the viruses are to establish a latent infection in neurons after lytic infection at the periphery. The alphaherpesvirus genes have been shown to fall into several major groups (designated alpha, beta, and gamma) whose expression is
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