Results 1 to 10 of about 163,576 (316)

Herpes simplex Virus

Intervirology, 1997
CNS infections caused by human herpesvirus 1 and human herpesvirus 2-herpes simplex virus type 1 and herpes simplex virus type 2--are reviewed. The major diseases associated with these viruses are meningitis and encephalitis. Two forms of encephalitis are known, neonatal encephalitis and encephalitis occurring after the neonatal period.
Klapper, P. E., Cleator, G. M.
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Herpes simplex virus type 2: epidemiology and management options in developing countries [PDF]

, 2007
Genital herpes simplex virus type 2 (HSV2) is highly prevalent worldwide and an increasingly important cause of genital ulcer disease (GUD). Continued HSV2 transmission is facilitated by the large number of undiagnosed cases, the frequency of atypical ...
Geretti, AM, Paz-Bailey, G., Ramaswamy, M., Paz-Bailey, G, Hawkes, SJ, Hawkes, S. J., Geretti, A. M., Ramaswamy, M   +7 more
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Herpes simplex virus interferes with amyloid precursor protein processing [PDF]

, 2005
Background The early events underlying Alzheimer's disease (AD) remain uncertain, although environmental factors may be involved. Work in this laboratory has shown that the combination of herpes simplex virus type 1 (HSV1) in brain and carriage of the
Itzhaki Ruth F, Suzanne J Shipley, Parkin, Edward T., Shipley, S.J., Edward T Parkin, Itzhaki, Ruth F., Shipley, Suzanne J., Dobson, Curtis B.; id_orcid, Shipley Suzanne J, Dobson Curtis B, Dobson, Curtis B., Curtis B Dobson, Itzhaki, R.F., Parkin Edward T, Ruth F Itzhaki, Parkin, E.T., Dobson, C.B.   +16 more
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Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]

, 2011
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu, Frazer J. Rixon, Petermann, P., Rixon Frazer J., Rahn, E., Hsu Mei-Ju, Knebel-Mörsdorf, D., Geraghty, R.J., Dagmar Knebel-Mörsdorf, Rahn Elena, Philipp Petermann, Knebel-Mörsdorf Dagmar, Elena Rahn, Frazer J Rixon, Hsu, M.-J., Rixon, F.J., Petermann Philipp   +16 more
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Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. [PDF]

, 2007
BACKGROUND: Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated with increased genital shedding of human immunodeficiency virus type 1 (HIV-1) RNA and HIV-1 transmissibility. METHODS: We conducted a randomized,
Becquart, Pierre, Van de Perre, Philippe, Sanon, Anselme, Segondy, Michel, Weiss, Helen A, Andonaba, Jean-Baptiste, Vallo, Roselyne, ANRS 1285 Study Group, Sawadogo, Adrien, Nagot, Nicolas, Foulongne, Vincent, Vergne, Laurence, Mayaud, Philippe, Ouédraogo, Abdoulaye, Defer, Marie-Christine, Djagbaré, Didier, Konaté, Issouf   +16 more
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A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]

, 2012
Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Rixon Frazer J., Schmid Michael F., Rixon, Frazer J., Bhella David, David Bhella, Ryan H. Rochat (129683), Hecksel, Corey W., Rochat, Ryan H., Hecksel Corey W., Chiu Wah, Bhella, David, Chiu, Wah, Wah Chiu, Michael F. Schmid (129681), Michael F Schmid, Rochat Ryan H., Corey W Hecksel, Schmid, Michael F., David Bhella (129684), Frazer J. Rixon (129686), Frazer J Rixon, Corey W. Hecksel (129682), Ryan H Rochat, Wah Chiu (129685)   +23 more
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An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]

, 2011
Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Heather M. Coleman, Connor, V., Proenca, J.T., Michael P. Nicoll, Nicoll, M.P., Jane Arthur, Arthur, J., Preston, C.M., João T. Proença, Christopher M. Preston, Coleman, H.M., Efstathiou, S., Stacey Efstathiou, Viv Connor   +13 more
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Genetics of Herpes Simplex Virus.

Journal of Investigative Dermatology, 1984
The most direct approach to elucidating the roles of herpes simplex virus (HSV) proteins in the viral replicative cycle has been to isolate temperature-sensitive, cytolysis-resistant, and drug-resistant mutants that exhibit alterations in the synthesis or activity of these proteins.
Schaffer, Priscilla A., Weller, Sandra K., Pancake, Bette A., Coen, Donald M.   +3 more
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Herpes simplex virus pneumonia [PDF]

Virologie, 2020
Herpes simplex virus 1 (HSV-1) reactivation is frequent in intensive care unit patients (20% to 50%, depending on case-mix): it begins in the throat after 3 to 5 days of hospital stay, then progress towards the respiratory tract to reach the lung after 7 to 10 days.
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Herpes simplex virus type 2 trends in relation to the HIV epidemic in northern Malawi. [PDF]

, 2008
OBJECTIVES: It is unclear whether the high prevalence of herpes simplex virus type 2 (HSV-2) found in much of Africa predates the HIV epidemic or is, to some extent, a consequence of it.
Fine, P.E.M., Glynn, JR, Glynn, J.R., Mwanyongo, O., Crampin, A.C., Crampin, AC, Ngwira, B.M.M., Ngwira, BMM, Ndhlovu, R., Mwanyongo, O, Fine, PEM, Ndhlovu, R   +11 more
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