Results 41 to 50 of about 163,576 (316)

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Herpes simplex virus (HSV)

Uirusu, 2010
Herpes simplex virus (HSV), the prototype of the herpesvirus family, causes a variety of diseases in human. In this review, I focus on the molecular mechanism of HSV infection including recent advance on this research field.
openaire   +3 more sources

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density [PDF]

, 2006
Efforts in structural biology have targeted the systematic determination of all protein structures through experimental determination or modeling.
Baker, David, Rixon Frazer J, Baker David, Wedemeyer, W.J., Matthew L Baker, Jiang Wen, Chiu Wah, Baker, M.L., Chiu, Wah, Wah Chiu, Jiang, W., Baker, D., Chiu, W., Baker, Matthew L, Wedemeyer, William J, Rixon, Frazer J, Jiang, Wen, Baker Matthew L, Frazer J Rixon, Rixon, F.J., William J Wedemeyer, David Baker, Wedemeyer William J, Wen Jiang   +23 more
core   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Use of acyclovir for suppression of human immunodeficiency virus infection is not associated with genotypic evidence of herpes simplex virus type 2 resistance to acyclovir: analysis of specimens from three phase III trials.

, 2010
Herpes simplex virus type 2 (HSV-2) is the most common cause of genital ulcer disease and is a cofactor for HIV-1 acquisition and transmission. We analyzed specimens from three separate phase III trials of acyclovir (ACV) for prevention of HIV-1 ...
Kathy Baisley, Clare Tanton, Anna Wald, Rula Green Gladden, Connie Celum, Changalucha, John, Weiss, Helen A, David M. Koelle, Watson-Jones, Deborah, Jairam Lingappa, Helen A. Weiss, Richard J. Hayes, John Changalucha, Celum, Connie, Tanton, Clare, Hayes, Richard J, Deborah Watson-Jones, Gladden, Rula Green, Baisley, Kathy, Koelle, David M, Marshak, Joshua O, Wald, Anna, Lingappa, Jairam, Joshua O. Marshak   +23 more
core   +1 more source

Effect of genital herpes on cervicovaginal HIV shedding in women co-infected with HIV AND HSV-2 in Tanzania. [PDF]

, 2013
To compare the presence and quantity of cervicovaginal HIV among HIV seropositive women with clinical herpes, subclinical HSV-2 infection and without HSV-2 infection respectively; to evaluate the association between cervicovaginal HIV and HSV shedding ...
Riedner, Gabriele, Todd, J., Leonard Maboko, Mabey, David, Lyamuya Eligius, Rusizoka, M, Helen A Weiss, Lyamuya, E., Weiss, H. A., See Profile, Belec Laurent, Hoelscher Michael, Mabey David, Riedner, G., Weiss Helen A., Rusizoka, M., Hayes, R., Mary Rusizoka, Lyamuya, Eligius, Maboko, L., Helen A. Weiss, Maboko Leonard, Maboko, Leonard, Rusizoka, Mary, Rusizoka Mary, Jim Todd, Belec, Laurent, Hayes, R, Todd Jim, Weiss, Helen A, Hoelscher, M., Hayes Richard, Hoelscher, Michael, Laurent Belec, Weiss, H.A., Michael Hoelscher, Mabey, D, Riedner, G, Todd, Jim, Weiss, Helen A., Belec, L, Hayes, Richard, Richard Hayes, Gabriele Riedner, Belec, L., Mabey, D., Riedner Gabriele, Eligius Lyamuya, David Mabey   +48 more
core   +1 more source

Steroids for Drug‐Resistant Seizures and Prolonged Stroke‐Like Episode in a Patient With Sturge–Weber Syndrome: A Case Report

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Introduction Sturge–Weber syndrome (SWS) brain involvement has been associated with impairments in the blood–brain barrier (BBB) and microglial activation within involved cortical regions. Acute neurological crises, including seizures, stroke‐like episodes, and/or significant headaches, are common in these patients.
Brenna N. Keam, Fabiola A. Morales‐Vias, Siddharth S. Gupta, Doris D. Lin, Anne M. Comi   +4 more
wiley   +1 more source

The use of fluorescence microscopy to study the association between herpesviruses and intrinsic resistance factors [PDF]

, 2011
Intrinsic antiviral resistance is a branch of antiviral defence that involves constitutively expressed cellular proteins that act within individual infected cells.
Roger D. Everett, Roger Everett, Everett, R.D., Roger D. Everett   +3 more
core   +1 more source