Results 51 to 60 of about 1,214,794 (308)

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Seroprevalence of Anti- Herpes Simplex Virus Type2 IgG, IgM Antibodies Among Pregnant Women in Diyala Province

Diyala Journal of Medicine, 2019
Background: Herpes simplex virus type 2 (HSV-2) is the leading cause of genital ulcer disease worldwide. The acquisition of genital herpes during pregnancy has been associated with spontaneous abortion, prematurity, and congenital and neonatal herpes.
Abul-Razak SH Hasan , Abbas A Al-Duliami , Asmaa Haseeb Hwaid , Wasan A Mageed , Zeina Gany Fadeel   +4 more
doaj   +2 more sources

Impacto do laser de baixa intensidade na supressão de infecções pelos vírus Herpes simplex 1 e 2: estudo in vitro Impact of low-intensity laser on the suppression of infections caused by Herpes simplex viruses 1 and 2: in vitro study

Revista da Sociedade Brasileira de Medicina Tropical, 2009
O uso do laser de baixa intensidade na supressão de infecções pelos vírus Herpes simplex 1 e 2 foi avaliado após uma a cinco aplicações, sendo observada uma redução gradual na replicação dos vírus Herpes simplex 1 e 2 com 68,4% e 57,3% de inibição ...
Dennis de Carvalho Ferreira, Fernanda Otaviano Martins, Maria Teresa Villela Romanos   +2 more
doaj   +1 more source

Risk factors for herpes simplex virus type 2 and HIV among women at high risk in northwestern Tanzania: preparing for an HSV-2 intervention trial. [PDF]

, 2007
OBJECTIVES: To determine prevalence of and risk factors for herpes simplex virus type 2 (HSV-2) and HIV among women being screened for a randomized, controlled trial of HSV suppressive therapy in northwestern Tanzania. METHODS: Two thousand seven hundred
Mugeye, Kokugonza, Hayes, Richard J, Balira, Rebecca, Knight, Louise, Ross, David, Changalucha, John, Weiss, Helen A, Baisley, Kathy, Watson-Jones, Deborah, Rusizoka, Mary, Everett, Dean   +10 more
core   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Fatal fulminant herpes simplex hepatitis secondary to tongue piercing in an immunocompetent adult: a case report

Journal of Medical Case Reports, 2008
Introduction Herpes simplex infection is most commonly a benign, self-limiting disease with mucocutaneous lesions and mild viremia. Immunosuppressed patients are at a higher risk of disseminated infection, as are neonates and pregnant women.
Lakhan Shaheen E, Harle Lindsey
doaj   +1 more source

Purification of Herpes Simplex Virus

Journal of General Virology, 1974
Summary Herpes simplex virus was highly purified from host cell material with little loss of infectivity by the combination of isopycnic centrifuging in a three layered silica gradient and rate zonal centrifuging in dextran T 70 gradient. By layering three solutions of colloidal silica (24, 18 and 12%, w/v) on top of each other in the centrifuge tube ...
A G, Vahlne, J, Blomberg
openaire   +2 more sources

Effect of herpes simplex suppression on incidence of HIV among women in Tanzania. [PDF]

, 2008
BACKGROUND: Infection with herpes simplex virus type 2 (HSV-2) is associated with an increased risk of acquiring infection with the human immunodeficiency virus (HIV).
HSV trial team, Clare Tanton, Tim Clayton, Weiss, Helen A, Watson-Jones, Deborah, Hambleton, Ian, Louise Knight, Steering and Data Monitoring Committees, Laurent Belec, Kokugonza Mugeye, Tanton, Clare, Le Goff, Jerome, Deborah Watson-Jones, Ross, David, Knight, Louise, Baisley, Kathy, Hayes, Richard, Richard Hayes, Everett, Dean, Clayton, Tim, Kathy Baisley, Mugeye, Kokugonza, Changalucha, John, Mary Rusizoka, Helen A. Weiss, Jerome Le Goff, John Changalucha, Dean Everett, Balira, Rebecca, Ian Hambleton, Rebecca Balira, Rusizoka, Mary, David Ross, Belec, Laurent   +33 more
core   +1 more source