Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]
Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu +16 more
core +1 more source
Seroepidemiological study of herpes simplex virus types 1 and 2 in Brazil, Estonia, India, Morocco, and Sri Lanka [PDF]
Background: The association between herpes simplex virus type 2 (HSV-2) and human immunodeficiency virus (HIV) and the development of HSV vaccines have increased interest in the study of HSV epidemiology.Objectives: To estimate the age and sex specific ...
Rbai, M +16 more
core +1 more source
Reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus. [PDF]
BACKGROUND: Epidemiologic data suggest that infection with herpes simplex virus type 2 (HSV-2) is associated with increased genital shedding of human immunodeficiency virus type 1 (HIV-1) RNA and HIV-1 transmissibility. METHODS: We conducted a randomized,
Becquart, Pierre +16 more
core +1 more source
Herpes Simplex Virus Infection Mimicking Bullous Disease in an Immunocompromised Patient
Immunodeficient patients are at risk of developing extended or atypical herpes simplex virus infections, which can be easily misdiagnosed. We present the case of a 79-year-old, treatment-induced (oral corticosteroid), immunocompromised female with an ...
Anne L.Y. Lecluse +1 more
doaj +1 more source
Genetics of Herpes Simplex Virus.
The most direct approach to elucidating the roles of herpes simplex virus (HSV) proteins in the viral replicative cycle has been to isolate temperature-sensitive, cytolysis-resistant, and drug-resistant mutants that exhibit alterations in the synthesis or activity of these proteins.
Schaffer, Priscilla A. +3 more
openaire +2 more sources
An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]
Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Heather M. Coleman +13 more
core +1 more source
Erythema Multiforme Attributable to Herpes Simplex Virus: Clinical Aspects and Treatment
Erythema multiforme is an acute mucocutaneous hypersensitivity reaction with various etiological factors, including herpes simplex virus, medications, autoimmune diseases, and malignancies, but the most common cause is infection by herpes simplex virus ...
Aya Mtiri +5 more
doaj +1 more source
Amnestic disorder associated with Kluver Bucy syndrome after HSV encephalitis: A case report (tur)
Encephalitis is an infection of the brain parenchyma and herpesviruses, enterovirular and paramyxoviruses are among the causes of viral encephalitis. Herpes Simplex Virus is one of the most common causes of encephalitis.
Neslihan Kara +2 more
doaj +1 more source
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes [PDF]
Components of promyelocytic leukaemia (PML) nuclear bodies (ND10) are recruited to sites associated with herpes simplex virus type 1 (HSV-1) genomes soon after they enter the nucleus. This cellular response is linked to intrinsic antiviral resistance and
Delphine Cuchet-Lourenço +24 more
core +1 more source
A Randomized Double-Blind Placebo Controlled Trial of Oral Acyclovir in Renal Allograft Recipients
Fifty renal transplant patients were randomized to receive either 800 mg acyclovir by mouth four times daily or identical placebo tablets for prophylaxis of herpes simplex infection. Patients were followed weekly to assess reactivation of herpes simplex,
Walter F Schlech +5 more
doaj +1 more source

