Seroprevalence, predictors and estimated incidence of maternal and neonatal Herpes Simplex Virus Type 2 infection in semi-urban women in Kilifi, Kenya [PDF]
Background: Herpes Simplex Virus type 2 (HSV-2) has public health importance as a leading cause of genital ulcers, a co-factor in HIV-1 acquisition and transmission and as a cause of neonatal herpes infections.
Awuondo Ken +35 more
core +1 more source
SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes [PDF]
Components of promyelocytic leukaemia (PML) nuclear bodies (ND10) are recruited to sites associated with herpes simplex virus type 1 (HSV-1) genomes soon after they enter the nucleus. This cellular response is linked to intrinsic antiviral resistance and
Delphine Cuchet-Lourenço +24 more
core +1 more source
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala +6 more
wiley +1 more source
Recombination with Herpes Simplex Virus [PDF]
Summary: The behaviour of six strains of herpes simplex virus was studied. Marked differences were noted in the type of lesion formed and the rate of attachment when the strains were inoculated on to the chorio-allantois, and in the behaviour of strains inoculated intracerebrally into mice or on to the cornea of the rabbit.
openaire +2 more sources
Therapeutic hypothermia for severe adult Herpes simplex virus encephalitis [PDF]
Despite antiviral treatment and advances in critical care, the Herpes simplex encephalitis (HSE) still has a poor outcome in a significant portion of patients.
Baršić, Bruno, Kutleša, Marko
core +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Herpes simplex virus triggers and then disarms a host antiviral response
Virus infection induces an antiviral response that is predominantly associated with the synthesis and secretion of soluble interferon. Here, we report that herpes simplex virus type 1 virions induce an interferon-independent antiviral state in human ...
Smiley, J R +5 more
core +1 more source
Effect of herpes simplex suppression on incidence of HIV among women in Tanzania. [PDF]
BACKGROUND: Infection with herpes simplex virus type 2 (HSV-2) is associated with an increased risk of acquiring infection with the human immunodeficiency virus (HIV).
HSV trial team +33 more
core +1 more source
Risk factors for herpes simplex virus type 2 and HIV among women at high risk in northwestern Tanzania: preparing for an HSV-2 intervention trial. [PDF]
OBJECTIVES: To determine prevalence of and risk factors for herpes simplex virus type 2 (HSV-2) and HIV among women being screened for a randomized, controlled trial of HSV suppressive therapy in northwestern Tanzania. METHODS: Two thousand seven hundred
Mugeye, Kokugonza +10 more
core +1 more source
Possible reasons for an increase in the proportion of genital ulcers due to herpes simplex virus from a cohort of female bar workers in Tanzania [PDF]
Objectives: To determine trends in the prevalence and aetiological distribution of genital ulcer syndrome (GUS) in a cohort of female bar workers and to assess factors associated with these trends.Methods: An open cohort of 600 women at high risk of HIV ...
Riedner, Gabriele +10 more
core +1 more source

