HSV-1 genome subnuclear positioning and associations with host-cell PML-NBs and centromeres regulate LAT locus transcription during latency in neurons. [PDF]
, 2012 Major human pathologies are caused by nuclear replicative viruses establishing life-long latent infection in their host. During latency the genomes of these viruses are intimately interacting with the cell nucleus environment.
Catez, Frédéric +8 more
core +13 more sources
Intervirology, 1997 CNS infections caused by human herpesvirus 1 and human herpesvirus 2-herpes simplex virus type 1 and herpes simplex virus type 2--are reviewed. The major diseases associated with these viruses are meningitis and encephalitis. Two forms of encephalitis are known, neonatal encephalitis and encephalitis occurring after the neonatal period.
Klapper, P. E., Cleator, G. M.
openaire +4 more sources
Herpes simplex virus pneumonia [PDF]
Virologie, 2020 Herpes simplex virus 1 (HSV-1) reactivation is frequent in intensive care unit patients (20% to 50%, depending on case-mix): it begins in the throat after 3 to 5 days of hospital stay, then progress towards the respiratory tract to reach the lung after 7 to 10 days.
openaire +3 more sources
Guillain-Barre syndrome presenting with sensory disturbance following a herpes virus infection: a case report [PDF]
, 2011 Introduction We present a case of an unusual clinical manifestation of Guillain-Barre syndrome following a pre-existing herpes virus infection. Although there have been several reports describing the co-existence of herpes virus infection and Guillain ...
Fotinie Ntziora +4 more
core +2 more sources
Prevalence of herpes simplex, Epstein Barr and human papilloma viruses in oral lichen planus [PDF]
, 2011 Objectives: The aim of the present study was to assess the prevalence of Herpes Simplex virus, Epstein Barr virus and Human Papilloma virus -16 in oral lichen planus cases and to evaluate whether any clinical variant, histopathological or demographic ...
Demir, Cem +2 more
core +1 more source
A successfully treated case of herpes simplex encephalitis complicated by subarachnoid bleeding: a case report [PDF]
, 2010 Introduction Histopathologically, herpes simplex virus type 1 causes hemorrhagic necrosis. Overt hemorrhage is infrequent in herpes simplex virus encephalitis but can lead to poor outcomes.
Okuchi Kazuo +5 more
core +1 more source
Coping Strategies and Behavioral Changes Following a Genital Herpes Diagnosis Among an Urban Sample of Underserved Midwestern Women [PDF]
, 2015 This study focused on understanding the coping strategies and related behavioural changes of women who were recently diagnosed with herpes simplex virus type 2.
Brand, Juanita Ebert +4 more
core +1 more source
Herpes simplex keratitis: Challenges in diagnosis and clinical management [PDF]
, 2017 Herpes simplex virus is responsible for numerous ocular diseases, the most common of which is herpetic stromal keratitis. This is a recurrent infection of the cornea that typically begins with a subclinical infection of the cornea that establishes a ...
Azher, Tayaba N +4 more
core +3 more sources
Oncolytic herpes viruses, chemotherapeutics, and other cancer drugs [PDF]
, 2013 Oncolytic viruses are emerging as a potential new way of treating cancers. They are selectively replication-competent viruses that propagate only in actively dividing tumor cells but not in normal cells and, as a result, destroy the tumor cells by ...
Braidwood, L. +3 more
core +1 more source
Immune- and nonimmune-compartment-specific interferon responses are critical determinants of herpes simplex virus-induced generalized infections and acute liver failure [PDF]
, 2016 The interferon (IFN) response to viral pathogens is critical for host survival. In humans and mouse models, defects in IFN responses can result in lethal herpes simplex virus 1 (HSV-1) infections, usually from encephalitis.
Leib, David A +3 more
core +3 more sources