Results 1 to 10 of about 5,285 (114)
Intrinsically disordered regions are abundant in simplexvirus proteomes and display signatures of positive selection [PDF]
Virus Evolution, 2020 Abstract Whereas the majority of herpesviruses co-speciated with their mammalian hosts, human herpes simplex virus 2 (HSV-2, genus Simplexvirus) most likely originated from the cross-species transmission of chimpanzee herpesvirus 1 to an ancestor of modern humans. We exploited the peculiar evolutionary history of HSV-2 to investigate the
Mario Clerici +2 more
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Evolution-guided prioritization identifies a tissue-specific phosphorylation switch on herpes simplex virus 1 UL7 regulating viral replication and pathogenicity [PDF]
Journal of VirologyAlthough numerous phosphorylation sites on herpes simplex virus 1 (HSV-1) proteins have been identified through phosphoproteomic analyses, their virological significance remains largely unclear.
Akihisa Kato +7 more
doaj +2 more sources
Genus Simplexvirus: Life cycle
Acta Microbiologica Bulgarica, 2023 The two same-name members of the subfamily Alphaherpesvirinae, the human herpesviruses Herpes simplex virus-1 (HSV-1) and Herpes simplex virus-2 (HSV-2), use human epithelial cells to establish their lytic phase, and neuronal cells to establish a lysogenic (latent) phase.
N. Hristova, A.S. Galabov
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Pathogenesis, Diseases, Immune Response, and Chemotherapy of Genus Simplexvirus
Acta Microbiologica Bulgarica, 2023 Throughout evolution, members of the genus Simplexvirus have evolved a highly effective pathoge¬netic strategy based on biomolecular interactions with pathogen-sensitive biological species. This in turn leads to pathogen-associated recurrent diseases with a wide range of clinical manifestations, including her¬petic encephalitis (HSE), herpetic ...
N. Hristova, A.S. Galabov
exaly +2 more sources
Herpes B virus and the neglected risk of zoonotic spillover [PDF]
One HealthObjectives: To evaluate the zoonotic risk of Simplexvirus macacine alpha 1 (B virus), a macaque-associated alphaherpesvirus that can cause severe and frequently fatal encephalitis in humans, and to assess the potential for cross-border risk through ...
Yujin Kim, Ji Min Lee, Jung Joo Hong
doaj +2 more sources
Antiviral Efficacy of Coridothymus capitatus Essential Oil Against HSV-1 and HSV-2 [PDF]
LifeCoridothymus capitatus is a perennial herb with aromatic leaves and flowers, distinct from Thymus vulgaris in its chemical composition, resulting in a unique Thymus Essential Oil (TEO).
Virginia Fuochi +3 more
doaj +2 more sources
Вопросы вирусологии, 2020 RETRACTED Herpes simplex viruses types 1 (HSV-1) and 2 (HSV-2) are among the most common viruses in the human population. The clinical manifestations of HSV infection vary widely, which necessitates reliable molecular methods for the timely diagnosis of ...
O. V. Sergeyev +2 more
doaj +4 more sources
Вопросы вирусологии, 2021 Introduction. Herpes simplex viruses type 1 (HSV-1) are extremely widespread throughout the world and, similar to other herpesviruses, establish lifelong persistent infection in the host.
V. L. Andronova +5 more
doaj +5 more sources
CRISPR/Cas9 Reduces Viral Load in a BALB/c Mouse Model of Ocular Herpes Infection [PDF]
BiomedicinesBackground/Objectives: Simplexvirus humanalpha1 (HSV-1) can cause herpetic keratitis, which is the most common cause of infectious blindness in developed countries.
Luiza Silveira Garcia +6 more
doaj +2 more sources
Biotechnology and Biotechnological Equipment, 2023 Astragalus glycyphyllos L. is widely used in Bulgarian folk medicine. Extracts from this plant have antiproliferative, antitumor and immune stimulating effects in vitro and in vivo. The aim of this study was to examine the potential antiviral activity of
Aleksandar Shkondrov +2 more
exaly +3 more sources