Results 21 to 30 of about 6,061 (140)

Antiviral effect of novel purine conjugate LAS-131 against Herpes simplex virus type 1 (Herpesviridae: Alphaherpesvirinae: Simplexvirus: Human alphaherpesvirus 1) in vitro

Вопросы вирусологии, 2021
Introduction. Herpes simplex viruses type 1 (HSV-1) are extremely widespread throughout the world and, similar to other herpesviruses, establish lifelong persistent infection in the host.
V. L. Andronova, G. A. Galegov, V. V. Musiyak, O. A. Vozdvizhenskaya, G. L. Levit, V. P. Krasnov   +5 more
doaj   +5 more sources

Antiviral activity of the organic germanium complex with aciclovir against herpes simplex virus (Herpesviridae: Alphaherpesvirinae: Simplexvirus: Human alphaherpesvirus 1/2) in the in vitro and in vivo systems

Вопросы вирусологии, 2021
Introduction. A significant increase in the incidence of various forms of herpesvirus infection (HVI) determines the need to search for new approaches to the modification of one of the basic antiviral drugs aciclovir (ACV) and its dosage forms to improve
L. M. Alimbarova, I. V. Ambrosov, S. K. Matelo, I. F. Barinsky   +3 more
doaj   +4 more sources

CRISPR-Cas genome editing system in the diagnosis and therapy of infection caused by herpes simplex virus type 1 (Orthoherpesviridae: Alphaherpesviridae: Simplexvirus: Simplexvirus humanalpha1)

Вопросы вирусологии
Herpes simplex virus type 1 (HSV-1), newly named as Simplexvirus humanalpha1 is one of the most common pathogens in the human population, which can cause severe disease, often with fatal outcomes.
Natalia A. Demidova, Regina R. Klimova, Alla A. Kushch, Dmitry S. Karpov   +3 more
doaj   +3 more sources

Characteristics of the pulmonary microbiota in patients with mild and severe pulmonary infection [PDF]

Frontiers in Cellular and Infection Microbiology, 2023
BackgroundLung infection is a global health problem associated with high morbidity and mortality and increasing rates of hospitalization. The correlation between pulmonary microecology and infection severity remains unclear.
Danting Zhan, Dan Li, Ke Yuan, Yihua Sun, Lijuan He, Jiacheng Zhong, Lingwei Wang   +6 more
doaj   +2 more sources

Antiviral potential of combinations of etiotropic antiherpetic agents including LAS-131, a novel terminase complex inhibitor, to affect the reproduction of herpes simplex virus type 1 (Orthoherpesviridae: Simplexvirus: Simplexvirus humanalpha1)

Вопросы вирусологии
Introduction. Herpes simplex virus type 1 (HSV-1) causes various diseases in humans that can lead to disability and death. Current treatments are effective and relatively safe.
Georgy A. Galegov, Valeriya L. Andronova, Olga A. Vozdvizhenskaya, Galina L. Levit, Valery N. Charushin, Victor P. Krasnov   +5 more
doaj   +2 more sources

Antiviral activity of extracts of basidiomycetes and humic compounds substances against Human Immunodeficiency Virus (Retroviridae: Orthoretrovirinae: Lentivirus: Human immunodeficiency virus 1) and Herpes Simplex Virus (Herpesviridae: Simplexvirus: Human alphaherpesvirus 1)

Вопросы вирусологии, 2020
Introduction. One of the most urgent problem of modern medicine is the fight against the disease caused by the Human Immunodeficiency Virus (HIV) – HIV infection. The chemical compounds have improved the situation for infected people, but they are toxic,
D. N. Nosik, N. N. Nosik, T. V. Teplyakova, O. A. Lobach, I. A. Kiseleva, N. G. Kondrashina, M. S. Bochkova, G. G. Ananko   +7 more
doaj   +4 more sources

Generation, characterization, and application of caprine herpesvirus 1 secreted glycoprotein D [PDF]

Microbiology Spectrum
Caprine herpesvirus 1 (CpHV-1), a member of the Herpesvirales order, Herpesviridae family, Alphaherpesvirinae subfamily, and Simplexvirus genus, is classically associated with two distinct clinical syndromes.
Sergio Minesso, Amienwanlen Eugene Odigie, Valentina Franceschi, Simone Taddei, Vittorio Madia, Maria Tempesta, Gaetano Donofrio   +6 more
doaj   +2 more sources

Equine histones are mobilized within equid alphaherpesvirus 1 (EHV1) replication compartments [PDF]

Journal of Virology
Equid alphaherpesvirus 1 (EHV1) is a DNA virus that causes severe disease in equids. Some strains are neurotropic and cause disease in the central nervous system, whereas others are non-neurotropic and can cause negative reproductive outcomes. Mechanisms
Kristen L. Conn
doaj   +2 more sources

A broad wastewater screening and clinical data surveillance for virus-related diseases in the metropolitan Detroit area in Michigan [PDF]

Human Genomics
Background Periodic bioinformatics-based screening of wastewater for assessing the diversity of potential human viral pathogens circulating in a given community may help to identify novel or potentially emerging infectious diseases.
Yabing Li, Brijen Miyani, Russell A. Faust, Randy E. David, Irene Xagoraraki   +4 more
doaj   +2 more sources

Occurrence and Molecular Characterization of Alphaherpesvirus in Psittacines in the State of Mato Grosso. [PDF]

Vet Med Int
The Alphaherpesvirinae subfamily belongs to the Orthoherpesviridae family, whose viruses are characterized by rapid replication and the ability to establish latent infection in host cells. These viruses cause important avian diseases such as Marek’s disease, infectious laryngotracheitis, and Pacheco’s disease (PD) in psittacines. In Brazilian avifauna,
da Silva TR, Costa MTDS, Moraes DFDSD, Vani CRA, Stering ACDS, Dutra V, Nakazato L.   +6 more
europepmc   +2 more sources