Discovery and development of safe-in-man broad-spectrum antiviral agents
Viral diseases are one of the leading causes of morbidity and mortality in the world. Virus-specific vaccines and antiviral drugs are the most powerful tools to combat viral diseases. However, broad-spectrum antiviral agents (BSAAs, i.e.
Petter I. Andersen +12 more
doaj +4 more sources
Silver Nanoparticles as Potential Antiviral Agents
Since the early 1990s, nanotechnology has led to new horizons in nanomedicine, which encompasses all spheres of science including chemistry, material science, biology, and biotechnology.
Zubair Ahmed Ratan +9 more
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Repurposing antiviral agents against mucormycosis. [PDF]
Mucormycosis is a life-threatening fungal infection with limited treatment options and high mortality rates among immunocompromised individuals. To identify new therapeutic strategies, we screened a library of 618 antiviral compounds against Rhizopus ...
Ammar A Khan +2 more
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AntiviralDB: an expert-curated database of antiviral agents against human infectious diseases [PDF]
Viral infectious diseases have caused millions of deaths worldwide. Antiviral agents are critical for controlling these infections; however, an open-access database dedicated specifically to antiviral agents remains unavailable.
Jie Huang +10 more
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Molecular Mechanisms of Antiviral Agents against Dengue Virus
Dengue is a major global health threat causing 390 million dengue infections and 25,000 deaths annually. The lack of efficacy of the licensed Dengvaxia vaccine and the absence of a clinically approved antiviral against dengue virus (DENV) drive the ...
Michelle Felicia Lee +2 more
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Medicinal Plants as Effective Antiviral Agents and Their Potential Benefits
This paper explores a diverse field of medicinal plants as potential antiviral agents, and delves into utilization of plant medicine for combating viral infections, emphasizing recent surge in research on natural products from plants as antiviral agents.
Gabriel Atampugbire +2 more
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Inhaled Dry Powder of Antiviral Agents: A Promising Approach to Treating Respiratory Viral Pathogens [PDF]
Inhaled dry powder formulations of antiviral agents represent a novel and potentially transformative approach to managing respiratory viral infections. Traditional antiviral therapies in the form of tablets or capsules often face limitations in terms of ...
Tushar Saha +5 more
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Carbazole Derivatives as Antiviral Agents: An Overview
Viruses represent the most common cause of infectious diseases worldwide and those with rapid propagation and high infection rates cause human and animal pandemics. These fast-spreading diseases are generally treated with antiviral drugs but, often, drug
Anna Caruso +7 more
doaj +3 more sources
Selected Plant Triterpenoids and Their Derivatives as Antiviral Agents. [PDF]
The results of the most recent investigation of triterpenoid-based antiviral agents namely in the HIV-1 and HSV-1 treatment were reviewed and summarized.
Wimmerová M, Bildziukevich U, Wimmer Z.
europepmc +2 more sources
Breaking the chains: Advancements in antiviral strategies to combat Nipah virus infections [PDF]
Nipah virus (NiV) is a highly pathogenic zoonotic virus that has caused several outbreaks with high fatality rates in humans and animals, thus, requiring a “One Health” approach. No specific treatment or vaccine is available for NiV infection, making the
Fredmoore L. Orosco
doaj +1 more source

